Identity
HGNC
LOCATION
10q21.3
LOCUSID
ALIAS
CXXC6,LCX,bA119F7.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80312
MIM: 607790
HGNC: 29484
Ensembl: ENSG00000138336
Variants:
dbSNP: 80312
ClinVar: 80312
TCGA: ENSG00000138336
COSMIC: TET1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000138336 | ENST00000373644 | Q8NFU7 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| Epigenetic regulation of gene expression | REACTOME | R-HSA-212165 |
| TET1,2,3 and TDG demethylate DNA | REACTOME | R-HSA-5221030 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37610277 | 2024 | TET1 Regulates Skeletal Stem-Cell Mediated Cartilage Regeneration. | 1 |
| 37995981 | 2024 | TET1 regulates stem cell properties and cell cycle of Cancer stem cells in triple-negative breast cancer via DNA demethylation. | 1 |
| 38369780 | 2024 | TET1 inhibits liver fibrosis by blocking hepatic stellate cell activation. | 0 |
| 38431880 | 2024 | TET1 inhibits the migration and invasion of cervical cancer cells by regulating autophagy. | 0 |
| 37610277 | 2024 | TET1 Regulates Skeletal Stem-Cell Mediated Cartilage Regeneration. | 1 |
| 37995981 | 2024 | TET1 regulates stem cell properties and cell cycle of Cancer stem cells in triple-negative breast cancer via DNA demethylation. | 1 |
| 38369780 | 2024 | TET1 inhibits liver fibrosis by blocking hepatic stellate cell activation. | 0 |
| 38431880 | 2024 | TET1 inhibits the migration and invasion of cervical cancer cells by regulating autophagy. | 0 |
| 36682704 | 2023 | TET1-mediated microRNA-188-5p promoter hydroxymethylation regulates PTEN/PI3K/AKT signaling pathway in acute myeloid leukemia cells. | 0 |
| 36692670 | 2023 | High nuclear expression of DNMT1 in correlation with inactivation of TET1 portray worst prognosis among the cervical carcinoma patients: clinical implications. | 0 |
| 37020036 | 2023 | Hypoxia switches TET1 from being tumor-suppressive to oncogenic. | 0 |
| 37121742 | 2023 | Oxidative stress-induced TET1 upregulation mediates active DNA demethylation in human gastric epithelial cells. | 0 |
| 37347215 | 2023 | Functional polymorphisms of the TET1 gene increase the risk of neuroblastoma in Chinese children. | 5 |
| 37430206 | 2023 | MiR-183-5p promotes migration and invasion of prostate cancer by targeting TET1. | 1 |
| 37474847 | 2023 | Crosstalk between RNA m(6)A and DNA methylation regulates transposable element chromatin activation and cell fate in human pluripotent stem cells. | 3 |
Citation
Dessen P
TET1 (tet methylcytosine dioxygenase 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40227/tet1
