TEX10 (testis expressed 10)

2013-09-01 Affiliation

Identity

HGNC

TEX10

LOCATION

9q31.1

LOCUSID

54881

ALIAS

Ipi1,bA208F1.2

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 54881
MIM: 616717
HGNC: 25988
Ensembl: ENSG00000136891

Variants:

dbSNP: 54881
ClinVar: 54881
TCGA: ENSG00000136891
COSMIC: TEX10

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000136891	ENST00000374902	Q9NXF1
ENSG00000136891	ENST00000374902	A0A024R169
ENSG00000136891	ENST00000429235	A0A0A0MSR3
ENSG00000136891	ENST00000535814	Q9NXF1

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Gene Expression	REACTOME	R-HSA-74160
rRNA processing	REACTOME	R-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosol	REACTOME	R-HSA-6791226
rRNA processing in the nucleus and cytosol	REACTOME	R-HSA-8868773

PharmGKB

Entity ID	Name	Type	Evidence	Association	PK	PD	PMIDs
PA10066	duloxetine	Chemical	ClinicalAnnotation	associated		PD	29407288
PA447321	Depressive Disorder, Major	Disease	ClinicalAnnotation	associated		PD	29407288

References

Pubmed ID	Year	Title	Citations
21326211	2011	The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex.	46
25936917	2015	Tex10 Coordinates Epigenetic Control of Super-Enhancer Activity in Pluripotency and Reprogramming.	30
22872859	2012	Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.	26
23481573	2012	Overexpression of TEX101, a potential novel cancer marker, in head and neck squamous cell carcinoma.	2
30045663	2018	Tex10 is upregulated and promotes cancer stem cell properties and chemoresistance in hepatocellular carcinoma.	2
31638260	2019	Tex10 promotes stemness and EMT phenotypes in esophageal squamous cell carcinoma via the Wnt/β‑catenin pathway.	0

Citation

Dessen P

TEX10 (testis expressed 10)

Atlas Genet Cytogenet Oncol Haematol. 2013-09-01

Online version: http://atlasgeneticsoncology.org/gene/53512/tex10