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TF (transferrin)

Identity

Alias_symbol (synonym)PRO1557
PRO2086
Other aliasHEL-S-71p
TFQTL1
HGNC (Hugo) TF
LocusID (NCBI) 7018
Atlas_Id 46020
Location 3q22.1  [Link to chromosome band 3q22]
Location_base_pair Starts at 133746133 and ends at 133779006 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ALB (4q13.3) / TF (3q22.1)LGALS1 (22q13.1) / TF (3q22.1)PICALM (11q14.2) / TF (3q22.1)
TF (3q22.1) / ALB (4q13.3)TF (3q22.1) / CLDN4 (7q11.23)TF (3q22.1) / MATR3 (5q31.2)
TF (3q22.1) / NEAT1 (11q13.1)TF (3q22.1) / TF (3q22.1)TF (3q22.1) / TTL (2q13)
ZFAS1 (20q13.13) / TF (3q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TF   11740
Cards
Entrez_Gene (NCBI)TF  7018  transferrin
AliasesHEL-S-71p; PRO1557; PRO2086; TFQTL1
GeneCards (Weizmann)TF
Ensembl hg19 (Hinxton)ENSG00000091513 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000091513 [Gene_View]  chr3:133746133-133779006 [Contig_View]  TF [Vega]
ICGC DataPortalENSG00000091513
TCGA cBioPortalTF
AceView (NCBI)TF
Genatlas (Paris)TF
WikiGenes7018
SOURCE (Princeton)TF
Genetics Home Reference (NIH)TF
Genomic and cartography
GoldenPath hg38 (UCSC)TF  -     chr3:133746133-133779006 +  3q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TF  -     3q22.1   [Description]    (hg19-Feb_2009)
EnsemblTF - 3q22.1 [CytoView hg19]  TF - 3q22.1 [CytoView hg38]
Mapping of homologs : NCBITF [Mapview hg19]  TF [Mapview hg38]
OMIM190000   209300   
Gene and transcription
Genbank (Entrez)AF118093 AJ252279 AK126941 AK222755 AK293842
RefSeq transcript (Entrez)NM_001063
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TF
Cluster EST : UnigeneHs.518267 [ NCBI ]
CGAP (NCI)Hs.518267
Alternative Splicing GalleryENSG00000091513
Gene ExpressionTF [ NCBI-GEO ]   TF [ EBI - ARRAY_EXPRESS ]   TF [ SEEK ]   TF [ MEM ]
Gene Expression Viewer (FireBrowse)TF [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7018
GTEX Portal (Tissue expression)TF
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02787   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP02787  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP02787
Splice isoforms : SwissVarP02787
PhosPhoSitePlusP02787
Domaine pattern : Prosite (Expaxy)TRANSFERRIN_LIKE_1 (PS00205)    TRANSFERRIN_LIKE_2 (PS00206)    TRANSFERRIN_LIKE_3 (PS00207)    TRANSFERRIN_LIKE_4 (PS51408)   
Domains : Interpro (EBI)Serotransferrin_mammal    Transferrin    Transferrin-like_dom    Transferrin_Fe_BS   
Domain families : Pfam (Sanger)Transferrin (PF00405)   
Domain families : Pfam (NCBI)pfam00405   
Domain families : Smart (EMBL)TR_FER (SM00094)  
Conserved Domain (NCBI)TF
DMDM Disease mutations7018
Blocks (Seattle)TF
PDB (SRS)1A8E    1A8F    1B3E    1BP5    1BTJ    1D3K    1D4N    1DTG    1FQE    1FQF    1JQF    1N7W    1N7X    1N84    1OQG    1OQH    1RYO    1SUV    2HAU    2HAV    2O7U    2O84    3FGS    3QYT    3S9L    3S9M    3S9N    3SKP    3V83    3V89    3V8X    3VE1    4H0W    4X1B    4X1D    5DYH   
PDB (PDBSum)1A8E    1A8F    1B3E    1BP5    1BTJ    1D3K    1D4N    1DTG    1FQE    1FQF    1JQF    1N7W    1N7X    1N84    1OQG    1OQH    1RYO    1SUV    2HAU    2HAV    2O7U    2O84    3FGS    3QYT    3S9L    3S9M    3S9N    3SKP    3V83    3V89    3V8X    3VE1    4H0W    4X1B    4X1D    5DYH   
PDB (IMB)1A8E    1A8F    1B3E    1BP5    1BTJ    1D3K    1D4N    1DTG    1FQE    1FQF    1JQF    1N7W    1N7X    1N84    1OQG    1OQH    1RYO    1SUV    2HAU    2HAV    2O7U    2O84    3FGS    3QYT    3S9L    3S9M    3S9N    3SKP    3V83    3V89    3V8X    3VE1    4H0W    4X1B    4X1D    5DYH   
PDB (RSDB)1A8E    1A8F    1B3E    1BP5    1BTJ    1D3K    1D4N    1DTG    1FQE    1FQF    1JQF    1N7W    1N7X    1N84    1OQG    1OQH    1RYO    1SUV    2HAU    2HAV    2O7U    2O84    3FGS    3QYT    3S9L    3S9M    3S9N    3SKP    3V83    3V89    3V8X    3VE1    4H0W    4X1B    4X1D    5DYH   
Structural Biology KnowledgeBase1A8E    1A8F    1B3E    1BP5    1BTJ    1D3K    1D4N    1DTG    1FQE    1FQF    1JQF    1N7W    1N7X    1N84    1OQG    1OQH    1RYO    1SUV    2HAU    2HAV    2O7U    2O84    3FGS    3QYT    3S9L    3S9M    3S9N    3SKP    3V83    3V89    3V8X    3VE1    4H0W    4X1B    4X1D    5DYH   
SCOP (Structural Classification of Proteins)1A8E    1A8F    1B3E    1BP5    1BTJ    1D3K    1D4N    1DTG    1FQE    1FQF    1JQF    1N7W    1N7X    1N84    1OQG    1OQH    1RYO    1SUV    2HAU    2HAV    2O7U    2O84    3FGS    3QYT    3S9L    3S9M    3S9N    3SKP    3V83    3V89    3V8X    3VE1    4H0W    4X1B    4X1D    5DYH   
CATH (Classification of proteins structures)1A8E    1A8F    1B3E    1BP5    1BTJ    1D3K    1D4N    1DTG    1FQE    1FQF    1JQF    1N7W    1N7X    1N84    1OQG    1OQH    1RYO    1SUV    2HAU    2HAV    2O7U    2O84    3FGS    3QYT    3S9L    3S9M    3S9N    3SKP    3V83    3V89    3V8X    3VE1    4H0W    4X1B    4X1D    5DYH   
SuperfamilyP02787
Human Protein AtlasENSG00000091513
Peptide AtlasP02787
HPRD01811
IPIIPI00022463   IPI00022949   IPI00945626   IPI00877763   IPI00945661   IPI00945828   IPI00790648   IPI00945308   
Protein Interaction databases
DIP (DOE-UCLA)P02787
IntAct (EBI)P02787
FunCoupENSG00000091513
BioGRIDTF
STRING (EMBL)TF
ZODIACTF
Ontologies - Pathways
QuickGOP02787
Ontology : AmiGOretina homeostasis  platelet degranulation  protein binding  extracellular region  extracellular region  extracellular region  extracellular space  early endosome  late endosome  clathrin-coated pit  cellular iron ion homeostasis  ferrous iron binding  ferric iron binding  basal plasma membrane  cell surface  endosome membrane  ferric iron transmembrane transporter activity  apical plasma membrane  endocytic vesicle  clathrin-coated vesicle membrane  extrinsic component of external side of plasma membrane  cytoplasmic vesicle  regulation of protein stability  vesicle  transferrin transport  secretory granule lumen  basal part of cell  positive regulation of receptor-mediated endocytosis  positive regulation of receptor-mediated endocytosis  perinuclear region of cytoplasm  recycling endosome  iron ion homeostasis  membrane organization  extracellular exosome  cellular response to iron ion  blood microparticle  ferrous iron import across plasma membrane  transferrin receptor binding  transferrin receptor binding  HFE-transferrin receptor complex  
Ontology : EGO-EBIretina homeostasis  platelet degranulation  protein binding  extracellular region  extracellular region  extracellular region  extracellular space  early endosome  late endosome  clathrin-coated pit  cellular iron ion homeostasis  ferrous iron binding  ferric iron binding  basal plasma membrane  cell surface  endosome membrane  ferric iron transmembrane transporter activity  apical plasma membrane  endocytic vesicle  clathrin-coated vesicle membrane  extrinsic component of external side of plasma membrane  cytoplasmic vesicle  regulation of protein stability  vesicle  transferrin transport  secretory granule lumen  basal part of cell  positive regulation of receptor-mediated endocytosis  positive regulation of receptor-mediated endocytosis  perinuclear region of cytoplasm  recycling endosome  iron ion homeostasis  membrane organization  extracellular exosome  cellular response to iron ion  blood microparticle  ferrous iron import across plasma membrane  transferrin receptor binding  transferrin receptor binding  HFE-transferrin receptor complex  
Pathways : BIOCARTAThe role of FYVE-finger proteins in vesicle transport [Genes]   
Pathways : KEGGHIF-1 signaling pathway    Mineral absorption   
NDEx NetworkTF
Atlas of Cancer Signalling NetworkTF
Wikipedia pathwaysTF
Orthology - Evolution
OrthoDB7018
GeneTree (enSembl)ENSG00000091513
Phylogenetic Trees/Animal Genes : TreeFamTF
HOVERGENP02787
HOGENOMP02787
Homologs : HomoloGeneTF
Homology/Alignments : Family Browser (UCSC)TF
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTF [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TF
dbVarTF
ClinVarTF
1000_GenomesTF 
Exome Variant ServerTF
ExAC (Exome Aggregation Consortium)TF (select the gene name)
Genetic variants : HAPMAP7018
Genomic Variants (DGV)TF [DGVbeta]
DECIPHERTF [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTF 
Mutations
ICGC Data PortalTF 
TCGA Data PortalTF 
Broad Tumor PortalTF
OASIS PortalTF [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTF  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTF
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TF
DgiDB (Drug Gene Interaction Database)TF
DoCM (Curated mutations)TF (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TF (select a term)
intoGenTF
Cancer3DTF(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM190000    209300   
Orphanet795   
MedgenTF
Genetic Testing Registry TF
NextProtP02787 [Medical]
TSGene7018
GENETestsTF
Target ValidationTF
Huge Navigator TF [HugePedia]
snp3D : Map Gene to Disease7018
BioCentury BCIQTF
ClinGenTF
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7018
Chemical/Pharm GKB GenePA36457
Clinical trialTF
Miscellaneous
canSAR (ICR)TF (select the gene name)
Probes
Litterature
PubMed327 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTF
EVEXTF
GoPubMedTF
iHOPTF
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:59:07 CEST 2017

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