Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TFAM (transcription factor A, mitochondrial)

Identity

Alias_namesTCF6
TCF6L2
Other aliasMTDPS15
MTTF1
MTTFA
TCF6L1
TCF6L3
HGNC (Hugo) TFAM
LocusID (NCBI) 7019
Atlas_Id 52068
Location 10q21.1  [Link to chromosome band 10q21]
Location_base_pair Starts at 58385143 and ends at 58399230 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATP8B3 (19p13.3) / TFAM (10q21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TFAM   11741
Cards
Entrez_Gene (NCBI)TFAM  7019  transcription factor A, mitochondrial
AliasesMTDPS15; MTTF1; MTTFA; TCF6; 
TCF6L1; TCF6L2; TCF6L3
GeneCards (Weizmann)TFAM
Ensembl hg19 (Hinxton)ENSG00000108064 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108064 [Gene_View]  chr10:58385143-58399230 [Contig_View]  TFAM [Vega]
ICGC DataPortalENSG00000108064
TCGA cBioPortalTFAM
AceView (NCBI)TFAM
Genatlas (Paris)TFAM
WikiGenes7019
SOURCE (Princeton)TFAM
Genetics Home Reference (NIH)TFAM
Genomic and cartography
GoldenPath hg38 (UCSC)TFAM  -     chr10:58385143-58399230 +  10q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TFAM  -     10q21.1   [Description]    (hg19-Feb_2009)
EnsemblTFAM - 10q21.1 [CytoView hg19]  TFAM - 10q21.1 [CytoView hg38]
Mapping of homologs : NCBITFAM [Mapview hg19]  TFAM [Mapview hg38]
OMIM600438   617156   
Gene and transcription
Genbank (Entrez)AB451241 AB451366 AK312558 BC018628 BC029815
RefSeq transcript (Entrez)NM_001270782 NM_003201 NM_012251
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TFAM
Cluster EST : UnigeneHs.594250 [ NCBI ]
CGAP (NCI)Hs.594250
Alternative Splicing GalleryENSG00000108064
Gene ExpressionTFAM [ NCBI-GEO ]   TFAM [ EBI - ARRAY_EXPRESS ]   TFAM [ SEEK ]   TFAM [ MEM ]
Gene Expression Viewer (FireBrowse)TFAM [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7019
GTEX Portal (Tissue expression)TFAM
Protein : pattern, domain, 3D structure
UniP2ot/SWisrProtY0p059   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ00059  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ00059
Splice isoforms : SwissVarQ00059
PhosPhoSitePlusQ00059
Domaine pattern : Prosite (Expaxy)HMG_BOX_2 (PS50118)   
Domains : Interpro (EBI)HMG_box_dom   
Domain families : Pfam (Sanger)HMG_box (PF00505)    HMG_box_2 (PF09011)   
Domain families : Pfam (NCBI)pfam00505    pfam09011   
Domain families : Smart (EMBL)HMG (SM00398)  
Conserved Domain (NCBI)TFAM
DMDM Disease mutations7019
Blocks (Seattle)TFAM
PDB (SRS)3FGH    3TMM    3TQ6    4NNU    4NOD   
PDB (PDBSum)3FGH    3TMM    3TQ6    4NNU    4NOD   
PDB (IMB)3FGH    3TMM    3TQ6    4NNU    4NOD   
PDB (RSDB)3FGH    3TMM    3TQ6    4NNU    4NOD   
Structural Biology KnowledgeBase3FGH    3TMM    3TQ6    4NNU    4NOD   
SCOP (Structural Classification of Proteins)3FGH    3TMM    3TQ6    4NNU    4NOD   
CATH (Classification of proteins structures)3FGH    3TMM    3TQ6    4NNU    4NOD   
SuperfamilyQ00059
Human Protein AtlasENSG00000108064
Peptide AtlasQ00059
HPRD02702
IPIIPI00020928   IPI01018732   IPI00643708   IPI00644515   
Protein Interaction databases
DIP (DOE-UCLA)Q00059
IntAct (EBI)Q00059
FunCoupENSG00000108064
BioGRIDTFAM
STRING (EMBL)TFAM
ZODIACTFAM
Ontologies - Pathways
QuickGOQ00059
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription coactivator binding  chromatin binding  transcription factor activity, sequence-specific DNA binding  RNA binding  protein binding  nucleus  mitochondrion  mitochondrial matrix  cytosol  DNA-dependent DNA replication  regulation of transcription from RNA polymerase I promoter  transcription from RNA polymerase II promoter  transcription from mitochondrial promoter  transcription initiation from mitochondrial promoter  transcription initiation from mitochondrial promoter  mitochondrion organization  DNA binding, bending  heat shock protein binding  mitochondrial respiratory chain complex assembly  mitochondrial nucleoid  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  mitochondrial light strand promoter sense binding  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription coactivator binding  chromatin binding  transcription factor activity, sequence-specific DNA binding  RNA binding  protein binding  nucleus  mitochondrion  mitochondrial matrix  cytosol  DNA-dependent DNA replication  regulation of transcription from RNA polymerase I promoter  transcription from RNA polymerase II promoter  transcription from mitochondrial promoter  transcription initiation from mitochondrial promoter  transcription initiation from mitochondrial promoter  mitochondrion organization  DNA binding, bending  heat shock protein binding  mitochondrial respiratory chain complex assembly  mitochondrial nucleoid  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  mitochondrial light strand promoter sense binding  
Pathways : KEGGHuntington's disease   
NDEx NetworkTFAM
Atlas of Cancer Signalling NetworkTFAM
Wikipedia pathwaysTFAM
Orthology - Evolution
OrthoDB7019
GeneTree (enSembl)ENSG00000108064
Phylogenetic Trees/Animal Genes : TreeFamTFAM
HOVERGENQ00059
HOGENOMQ00059
Homologs : HomoloGeneTFAM
Homology/Alignments : Family Browser (UCSC)TFAM
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTFAM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TFAM
dbVarTFAM
ClinVarTFAM
1000_GenomesTFAM 
Exome Variant ServerTFAM
ExAC (Exome Aggregation Consortium)TFAM (select the gene name)
Genetic variants : HAPMAP7019
Genomic Variants (DGV)TFAM [DGVbeta]
DECIPHERTFAM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTFAM 
Mutations
ICGC Data PortalTFAM 
TCGA Data PortalTFAM 
Broad Tumor PortalTFAM
OASIS PortalTFAM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTFAM  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTFAM
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch TFAM
DgiDB (Drug Gene Interaction Database)TFAM
DoCM (Curated mutations)TFAM (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TFAM (select a term)
intoGenTFAM
Cancer3DTFAM(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600438    617156   
Orphanet
MedgenTFAM
Genetic Testing Registry TFAM
NextProtQ00059 [Medical]
TSGene7019
GENETestsTFAM
Target ValidationTFAM
Huge Navigator TFAM [HugePedia]
snp3D : Map Gene to Disease7019
BioCentury BCIQTFAM
ClinGenTFAM
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7019
Chemical/Pharm GKB GenePA36458
Clinical trialTFAM
Miscellaneous
canSAR (ICR)TFAM (select the gene name)
Probes
Litterature
PubMed158 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTFAM
EVEXTFAM
GoPubMedTFAM
iHOPTFAM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:34:46 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.