Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TFAP2E (transcription factor AP-2 epsilon)

Identity

Alias (NCBI)AP-2epsilon
AP2E
HGNC (Hugo) TFAP2E
HGNC Alias symbAP2E
AP-2epsilon
HGNC Previous nametranscription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
LocusID (NCBI) 339488
Atlas_Id 52562
Location 1p34.3  [Link to chromosome band 1p34]
Location_base_pair Starts at 35573314 and ends at 35595326 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TFAP2E   30774
Cards
Entrez_Gene (NCBI)TFAP2E    transcription factor AP-2 epsilon
AliasesAP-2epsilon; AP2E
GeneCards (Weizmann)TFAP2E
Ensembl hg19 (Hinxton)ENSG00000116819 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116819 [Gene_View]  ENSG00000116819 [Sequence]  chr1:35573314-35595326 [Contig_View]  TFAP2E [Vega]
ICGC DataPortalENSG00000116819
TCGA cBioPortalTFAP2E
AceView (NCBI)TFAP2E
Genatlas (Paris)TFAP2E
SOURCE (Princeton)TFAP2E
Genetics Home Reference (NIH)TFAP2E
Genomic and cartography
GoldenPath hg38 (UCSC)TFAP2E  -     chr1:35573314-35595326 +  1p34.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TFAP2E  -     1p34.3   [Description]    (hg19-Feb_2009)
GoldenPathTFAP2E - 1p34.3 [CytoView hg19]  TFAP2E - 1p34.3 [CytoView hg38]
ImmunoBaseENSG00000116819
Genome Data Viewer NCBITFAP2E [Mapview hg19]  
OMIM614428   
Gene and transcription
Genbank (Entrez)AY326454 BC041175 BC150147
RefSeq transcript (Entrez)NM_178548
Consensus coding sequences : CCDS (NCBI)TFAP2E
Gene ExpressionTFAP2E [ NCBI-GEO ]   TFAP2E [ EBI - ARRAY_EXPRESS ]   TFAP2E [ SEEK ]   TFAP2E [ MEM ]
Gene Expression Viewer (FireBrowse)TFAP2E [ Firebrowse - Broad ]
GenevisibleExpression of TFAP2E in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)339488
GTEX Portal (Tissue expression)TFAP2E
Human Protein AtlasENSG00000116819-TFAP2E [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6VUC0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6VUC0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6VUC0
PhosPhoSitePlusQ6VUC0
Domains : Interpro (EBI)TF_AP2    TF_AP2_C   
Domain families : Pfam (Sanger)TF_AP-2 (PF03299)   
Domain families : Pfam (NCBI)pfam03299   
Conserved Domain (NCBI)TFAP2E
SuperfamilyQ6VUC0
AlphaFold pdb e-kbQ6VUC0   
Human Protein Atlas [tissue]ENSG00000116819-TFAP2E [tissue]
HPRD18174
Protein Interaction databases
DIP (DOE-UCLA)Q6VUC0
IntAct (EBI)Q6VUC0
BioGRIDTFAP2E
STRING (EMBL)TFAP2E
ZODIACTFAP2E
Ontologies - Pathways
QuickGOQ6VUC0
Ontology : AmiGOchromatin  RNA polymerase II transcription regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  nucleus  regulation of transcription by RNA polymerase II  regulation of cell population proliferation  identical protein binding  positive regulation of transcription by RNA polymerase II  anatomical structure development  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBIchromatin  RNA polymerase II transcription regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  nucleus  regulation of transcription by RNA polymerase II  regulation of cell population proliferation  identical protein binding  positive regulation of transcription by RNA polymerase II  anatomical structure development  sequence-specific double-stranded DNA binding  
NDEx NetworkTFAP2E
Atlas of Cancer Signalling NetworkTFAP2E
Wikipedia pathwaysTFAP2E
Orthology - Evolution
OrthoDB339488
GeneTree (enSembl)ENSG00000116819
Phylogenetic Trees/Animal Genes : TreeFamTFAP2E
Homologs : HomoloGeneTFAP2E
Homology/Alignments : Family Browser (UCSC)TFAP2E
Gene fusions - Rearrangements
Fusion : QuiverTFAP2E
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTFAP2E [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TFAP2E
dbVarTFAP2E
ClinVarTFAP2E
MonarchTFAP2E
1000_GenomesTFAP2E 
Exome Variant ServerTFAP2E
GNOMAD BrowserENSG00000116819
Varsome BrowserTFAP2E
ACMGTFAP2E variants
VarityQ6VUC0
Genomic Variants (DGV)TFAP2E [DGVbeta]
DECIPHERTFAP2E [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTFAP2E 
Mutations
ICGC Data PortalTFAP2E 
TCGA Data PortalTFAP2E 
Broad Tumor PortalTFAP2E
OASIS PortalTFAP2E [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTFAP2E  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTFAP2E
Mutations and Diseases : HGMDTFAP2E
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTFAP2E
DgiDB (Drug Gene Interaction Database)TFAP2E
DoCM (Curated mutations)TFAP2E
CIViC (Clinical Interpretations of Variants in Cancer)TFAP2E
Cancer3DTFAP2E
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614428   
Orphanet
DisGeNETTFAP2E
MedgenTFAP2E
Genetic Testing Registry TFAP2E
NextProtQ6VUC0 [Medical]
GENETestsTFAP2E
Target ValidationTFAP2E
Huge Navigator TFAP2E [HugePedia]
ClinGenTFAP2E
Clinical trials, drugs, therapy
MyCancerGenomeTFAP2E
Protein Interactions : CTDTFAP2E
Pharm GKB GenePA134992283
PharosQ6VUC0
Clinical trialTFAP2E
Miscellaneous
canSAR (ICR)TFAP2E
HarmonizomeTFAP2E
DataMed IndexTFAP2E
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTFAP2E
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:34:51 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.