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TFB1M (transcription factor B1, mitochondrial)

Identity

Alias (NCBI)CGI-75
CGI75
mtTFB
mtTFB1
HGNC (Hugo) TFB1M
HGNC Alias symbmtTFB
CGI-75
HGNC Alias namedimethyladenosine transferase 1, mitochondrial
LocusID (NCBI) 51106
Atlas_Id 74652
Location 6q25.3  [Link to chromosome band 6q25]
Location_base_pair Starts at 155256130 and ends at 155314483 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ESR1 (6q25.1) / TFB1M (6q25.3)TIAM2 (6q25.3) / TFB1M (6q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  ESR1/TFB1M (6q25)


External links

Nomenclature
HGNC (Hugo)TFB1M   17037
Cards
Entrez_Gene (NCBI)TFB1M  51106  transcription factor B1, mitochondrial
AliasesCGI-75; CGI75; mtTFB; mtTFB1
GeneCards (Weizmann)TFB1M
Ensembl hg19 (Hinxton)ENSG00000029639 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000029639 [Gene_View]  ENSG00000029639 [Sequence]  chr6:155256130-155314483 [Contig_View]  TFB1M [Vega]
ICGC DataPortalENSG00000029639
TCGA cBioPortalTFB1M
AceView (NCBI)TFB1M
Genatlas (Paris)TFB1M
WikiGenes51106
SOURCE (Princeton)TFB1M
Genetics Home Reference (NIH)TFB1M
Genomic and cartography
GoldenPath hg38 (UCSC)TFB1M  -     chr6:155256130-155314483 -  6q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TFB1M  -     6q25.3   [Description]    (hg19-Feb_2009)
GoldenPathTFB1M - 6q25.3 [CytoView hg19]  TFB1M - 6q25.3 [CytoView hg38]
ImmunoBaseENSG00000029639
genome Data Viewer NCBITFB1M [Mapview hg19]  
OMIM607033   
Gene and transcription
Genbank (Entrez)AA405744 AF151833 AK022993 AK289484 BC005183
RefSeq transcript (Entrez)NM_001350501 NM_001350502 NM_016020
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TFB1M
Alternative Splicing GalleryENSG00000029639
Gene ExpressionTFB1M [ NCBI-GEO ]   TFB1M [ EBI - ARRAY_EXPRESS ]   TFB1M [ SEEK ]   TFB1M [ MEM ]
Gene Expression Viewer (FireBrowse)TFB1M [ Firebrowse - Broad ]
GenevisibleExpression of TFB1M in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51106
GTEX Portal (Tissue expression)TFB1M
Human Protein AtlasENSG00000029639-TFB1M [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WVM0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WVM0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WVM0
Splice isoforms : SwissVarQ8WVM0
Catalytic activity : Enzyme2.1.1.- [ Enzyme-Expasy ]   2.1.1.-2.1.1.- [ IntEnz-EBI ]   2.1.1.- [ BRENDA ]   2.1.1.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ8WVM0
Domaine pattern : Prosite (Expaxy)RRNA_A_DIMETH (PS01131)    SAM_RNA_A_N6_MT (PS51689)   
Domains : Interpro (EBI)KsgA/Erm    rRNA_Ade_diMease-like    rRNA_Ade_Mease_Trfase_CS    rRNA_Ade_methylase_Trfase_N    rRNA_adenine_dimethylase    SAM-dependent_MTases   
Domain families : Pfam (Sanger)RrnaAD (PF00398)   
Domain families : Pfam (NCBI)pfam00398   
Domain families : Smart (EMBL)rADc (SM00650)  
Conserved Domain (NCBI)TFB1M
DMDM Disease mutations51106
Blocks (Seattle)TFB1M
PDB (RSDB)6AAX    6AJK   
PDB Europe6AAX    6AJK   
PDB (PDBSum)6AAX    6AJK   
PDB (IMB)6AAX    6AJK   
Structural Biology KnowledgeBase6AAX    6AJK   
SCOP (Structural Classification of Proteins)6AAX    6AJK   
CATH (Classification of proteins structures)6AAX    6AJK   
SuperfamilyQ8WVM0
Human Protein Atlas [tissue]ENSG00000029639-TFB1M [tissue]
Peptide AtlasQ8WVM0
HPRD09515
IPIIPI00291525   
Protein Interaction databases
DIP (DOE-UCLA)Q8WVM0
IntAct (EBI)Q8WVM0
FunCoupENSG00000029639
BioGRIDTFB1M
STRING (EMBL)TFB1M
ZODIACTFB1M
Ontologies - Pathways
QuickGOQ8WVM0
Ontology : AmiGOrRNA modification  rRNA (adenine-N6,N6-)-dimethyltransferase activity  rRNA (adenine-N6,N6-)-dimethyltransferase activity  DNA binding  RNA binding  protein binding  mitochondrial matrix  mitochondrion organization  rRNA methylation  mitochondrial nucleoid  
Ontology : EGO-EBIrRNA modification  rRNA (adenine-N6,N6-)-dimethyltransferase activity  rRNA (adenine-N6,N6-)-dimethyltransferase activity  DNA binding  RNA binding  protein binding  mitochondrial matrix  mitochondrion organization  rRNA methylation  mitochondrial nucleoid  
NDEx NetworkTFB1M
Atlas of Cancer Signalling NetworkTFB1M
Wikipedia pathwaysTFB1M
Orthology - Evolution
OrthoDB51106
GeneTree (enSembl)ENSG00000029639
Phylogenetic Trees/Animal Genes : TreeFamTFB1M
HOGENOMQ8WVM0
Homologs : HomoloGeneTFB1M
Homology/Alignments : Family Browser (UCSC)TFB1M
Gene fusions - Rearrangements
Fusion : QuiverTFB1M
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTFB1M [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TFB1M
dbVarTFB1M
ClinVarTFB1M
1000_GenomesTFB1M 
Exome Variant ServerTFB1M
GNOMAD BrowserENSG00000029639
Varsome BrowserTFB1M
Genetic variants : HAPMAP51106
Genomic Variants (DGV)TFB1M [DGVbeta]
DECIPHERTFB1M [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTFB1M 
Mutations
ICGC Data PortalTFB1M 
TCGA Data PortalTFB1M 
Broad Tumor PortalTFB1M
OASIS PortalTFB1M [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTFB1M  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTFB1M
Mutations and Diseases : HGMDTFB1M
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch TFB1M
DgiDB (Drug Gene Interaction Database)TFB1M
DoCM (Curated mutations)TFB1M (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TFB1M (select a term)
intoGenTFB1M
Cancer3DTFB1M(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607033   
Orphanet12050   
DisGeNETTFB1M
MedgenTFB1M
Genetic Testing Registry TFB1M
NextProtQ8WVM0 [Medical]
TSGene51106
GENETestsTFB1M
Target ValidationTFB1M
Huge Navigator TFB1M [HugePedia]
snp3D : Map Gene to Disease51106
BioCentury BCIQTFB1M
ClinGenTFB1M
Clinical trials, drugs, therapy
Protein Interactions : CTD51106
Pharm GKB GenePA38198
Clinical trialTFB1M
Miscellaneous
canSAR (ICR)TFB1M (select the gene name)
HarmonizomeTFB1M
DataMed IndexTFB1M
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTFB1M
EVEXTFB1M
GoPubMedTFB1M
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Aug 22 19:37:44 CEST 2020

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