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TFDP1 (transcription factor Dp-1)

Identity

Alias_symbol (synonym)Dp-1
DRTF1
DP1
DILC
Other alias
HGNC (Hugo) TFDP1
LocusID (NCBI) 7027
Atlas_Id 42529
Location 13q34  [Link to chromosome band 13q34]
Location_base_pair Starts at 113584741 and ends at 113641473 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DCUN1D2 (13q34) / TFDP1 (13q34)FAM122C (Xq26.3) / TFDP1 (13q34)LOC100507412 (-) / TFDP1 (13q34)
NF1 (17q11.2) / TFDP1 (13q34)SHANK2 (11q13.3) / TFDP1 (13q34)TFDP1 (13q34) / CUL4A (13q34)
TFDP1 (13q34) / GRK1 (13q34)TFDP1 (13q34) / TMCO3 (13q34)TFDP1 (13q34) / TMEM255B (13q34)
TUBGCP3 (13q34) / TFDP1 (13q34)TFDP1 13q34 / CUL4A 13q34TFDP1 13q34 / TMCO3 13q34
TUBGCP3 13q34 / TFDP1 13q34

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TFDP1   11749
Cards
Entrez_Gene (NCBI)TFDP1  7027  transcription factor Dp-1
AliasesDILC; DP1; DRTF1; Dp-1
GeneCards (Weizmann)TFDP1
Ensembl hg19 (Hinxton)ENSG00000198176 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198176 [Gene_View]  chr13:113584741-113641473 [Contig_View]  TFDP1 [Vega]
ICGC DataPortalENSG00000198176
TCGA cBioPortalTFDP1
AceView (NCBI)TFDP1
Genatlas (Paris)TFDP1
WikiGenes7027
SOURCE (Princeton)TFDP1
Genetics Home Reference (NIH)TFDP1
Genomic and cartography
GoldenPath hg38 (UCSC)TFDP1  -     chr13:113584741-113641473 +  13q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TFDP1  -     13q34   [Description]    (hg19-Feb_2009)
EnsemblTFDP1 - 13q34 [CytoView hg19]  TFDP1 - 13q34 [CytoView hg38]
Mapping of homologs : NCBITFDP1 [Mapview hg19]  TFDP1 [Mapview hg38]
OMIM189902   
Gene and transcription
Genbank (Entrez)AK297114 AK298521 AK310401 AK313742 BC011685
RefSeq transcript (Entrez)NM_007111
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TFDP1
Cluster EST : UnigeneHs.79353 [ NCBI ]
CGAP (NCI)Hs.79353
Alternative Splicing GalleryENSG00000198176
Gene ExpressionTFDP1 [ NCBI-GEO ]   TFDP1 [ EBI - ARRAY_EXPRESS ]   TFDP1 [ SEEK ]   TFDP1 [ MEM ]
Gene Expression Viewer (FireBrowse)TFDP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7027
GTEX Portal (Tissue expression)TFDP1
Human Protein AtlasENSG00000198176-TFDP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14186   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14186  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14186
Splice isoforms : SwissVarQ14186
PhosPhoSitePlusQ14186
Domains : Interpro (EBI)DP-1    E2F_WHTH_DNA-bd_dom    Transc_factor_DP_C    Transcrpt_fac_DP    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)DP (PF08781)    E2F_TDP (PF02319)   
Domain families : Pfam (NCBI)pfam08781    pfam02319   
Domain families : Smart (EMBL)DP (SM01138)  E2F_TDP (SM01372)  
Conserved Domain (NCBI)TFDP1
DMDM Disease mutations7027
Blocks (Seattle)TFDP1
PDB (SRS)2AZE    5GOW   
PDB (PDBSum)2AZE    5GOW   
PDB (IMB)2AZE    5GOW   
PDB (RSDB)2AZE    5GOW   
Structural Biology KnowledgeBase2AZE    5GOW   
SCOP (Structural Classification of Proteins)2AZE    5GOW   
CATH (Classification of proteins structures)2AZE    5GOW   
SuperfamilyQ14186
Human Protein Atlas [tissue]ENSG00000198176-TFDP1 [tissue]
Peptide AtlasQ14186
HPRD01792
IPIIPI00029095   IPI01012465   IPI00955832   IPI00922297   IPI00647724   IPI00641864   
Protein Interaction databases
DIP (DOE-UCLA)Q14186
IntAct (EBI)Q14186
FunCoupENSG00000198176
BioGRIDTFDP1
STRING (EMBL)TFDP1
ZODIACTFDP1
Ontologies - Pathways
QuickGOQ14186
Ontology : AmiGOregulation of transcription involved in G1/S transition of mitotic cell cycle  RNA polymerase II regulatory region sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding  DNA binding transcription factor activity  transcription coactivator activity  protein binding  nucleus  nucleoplasm  nucleoplasm  mitochondrion  cytosol  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  transcription factor binding  cell proliferation  protein domain specific binding  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  negative regulation of G0 to G1 transition  negative regulation of fat cell proliferation  RNA polymerase II transcription factor complex  positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway  
Ontology : EGO-EBIregulation of transcription involved in G1/S transition of mitotic cell cycle  RNA polymerase II regulatory region sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding  DNA binding transcription factor activity  transcription coactivator activity  protein binding  nucleus  nucleoplasm  nucleoplasm  mitochondrion  cytosol  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  transcription factor binding  cell proliferation  protein domain specific binding  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  negative regulation of G0 to G1 transition  negative regulation of fat cell proliferation  RNA polymerase II transcription factor complex  positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway  
Pathways : BIOCARTAE2F1 Destruction Pathway [Genes]    Influence of Ras and Rho proteins on G1 to S Transition [Genes]    Cyclins and Cell Cycle Regulation [Genes]    Cyclin E Destruction Pathway [Genes]    Regulation of p27 Phosphorylation during Cell Cycle Progression [Genes]    Cell Cycle: G1/S Check Point [Genes]   
Pathways : KEGGTGF-beta signaling pathway    Cell cycle   
NDEx NetworkTFDP1
Atlas of Cancer Signalling NetworkTFDP1
Wikipedia pathwaysTFDP1
Orthology - Evolution
OrthoDB7027
GeneTree (enSembl)ENSG00000198176
Phylogenetic Trees/Animal Genes : TreeFamTFDP1
HOVERGENQ14186
HOGENOMQ14186
Homologs : HomoloGeneTFDP1
Homology/Alignments : Family Browser (UCSC)TFDP1
Gene fusions - Rearrangements
Fusion: TCGA_MDACCTFDP1 13q34 CUL4A 13q34 LUAD
Fusion: TCGA_MDACCTFDP1 13q34 TMCO3 13q34 BRCA
Fusion: TCGA_MDACCTUBGCP3 13q34 TFDP1 13q34 HNSC
Fusion PortalTFDP1 13q34 CUL4A 13q34 LUAD
Fusion PortalTFDP1 13q34 TMCO3 13q34 BRCA
Fusion PortalTUBGCP3 13q34 TFDP1 13q34 HNSC
Fusion : QuiverTFDP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTFDP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TFDP1
dbVarTFDP1
ClinVarTFDP1
1000_GenomesTFDP1 
Exome Variant ServerTFDP1
ExAC (Exome Aggregation Consortium)ENSG00000198176
GNOMAD BrowserENSG00000198176
Genetic variants : HAPMAP7027
Genomic Variants (DGV)TFDP1 [DGVbeta]
DECIPHERTFDP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTFDP1 
Mutations
ICGC Data PortalTFDP1 
TCGA Data PortalTFDP1 
Broad Tumor PortalTFDP1
OASIS PortalTFDP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTFDP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTFDP1
intOGen PortalTFDP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TFDP1
DgiDB (Drug Gene Interaction Database)TFDP1
DoCM (Curated mutations)TFDP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TFDP1 (select a term)
intoGenTFDP1
Cancer3DTFDP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM189902   
Orphanet
DisGeNETTFDP1
MedgenTFDP1
Genetic Testing Registry TFDP1
NextProtQ14186 [Medical]
TSGene7027
GENETestsTFDP1
Target ValidationTFDP1
Huge Navigator TFDP1 [HugePedia]
snp3D : Map Gene to Disease7027
BioCentury BCIQTFDP1
ClinGenTFDP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7027
Chemical/Pharm GKB GenePA36464
Clinical trialTFDP1
Miscellaneous
canSAR (ICR)TFDP1 (select the gene name)
Probes
Litterature
PubMed73 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTFDP1
EVEXTFDP1
GoPubMedTFDP1
iHOPTFDP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Feb 28 13:41:27 CET 2018

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