Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TFDP2 (transcription factor Dp-2)

Identity

Alias_namestranscription factor Dp-2 (E2F dimerization partner 2)
Alias_symbol (synonym)Dp-2
Other aliasDP2
HGNC (Hugo) TFDP2
LocusID (NCBI) 7029
Atlas_Id 42530
Location 3q23  [Link to chromosome band 3q23]
Location_base_pair Starts at 141944428 and ends at 142149544 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		DOCK1 (10q26.2) / TFDP2 (3q23)LANCL2 (7p11.2) / TFDP2 (3q23)PLS1 (3q23) / TFDP2 (3q23)
TFDP2 (3q23) / COG5 (7q22.3)TFDP2 (3q23) / GK5 (3q23)TFDP2 (3q23) / LANCL2 (7p11.2)
TFDP2 (3q23) / PLD1 (3q26.31)TFDP2 (3q23) / ZNF721 (4p16.3)LANCL2 7p11.2 / TFDP2 3q23
PLS1 3q23 / TFDP2 3q23TFDP2 3q23 / COG5 7q22.3TFDP2 3q23 / GK5 3q23
TFDP2 3q23 / LANCL2 7p11.2TFDP2 3q23 / PLD1 3q26.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TFDP2   11751
Cards
Entrez_Gene (NCBI)TFDP2  7029  transcription factor Dp-2
AliasesDP2
GeneCards (Weizmann)TFDP2
Ensembl hg19 (Hinxton)ENSG00000114126 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000114126 [Gene_View]  chr3:141944428-142149544 [Contig_View]  TFDP2 [Vega]
ICGC DataPortalENSG00000114126
TCGA cBioPortalTFDP2
AceView (NCBI)TFDP2
Genatlas (Paris)TFDP2
WikiGenes7029
SOURCE (Princeton)TFDP2
Genetics Home Reference (NIH)TFDP2
Genomic and cartography
GoldenPath hg38 (UCSC)TFDP2  -     chr3:141944428-142149544 -  3q23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TFDP2  -     3q23   [Description]    (hg19-Feb_2009)
EnsemblTFDP2 - 3q23 [CytoView hg19]  TFDP2 - 3q23 [CytoView hg38]
Mapping of homologs : NCBITFDP2 [Mapview hg19]  TFDP2 [Mapview hg38]
OMIM602160   
Gene and transcription
Genbank (Entrez)AB528993 AK096450 AK303181 AK303634 AK314786
RefSeq transcript (Entrez)NM_001178138 NM_001178139 NM_001178140 NM_001178141 NM_001178142 NM_006286
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TFDP2
Cluster EST : UnigeneHs.379018 [ NCBI ]
CGAP (NCI)Hs.379018
Alternative Splicing GalleryENSG00000114126
Gene ExpressionTFDP2 [ NCBI-GEO ]   TFDP2 [ EBI - ARRAY_EXPRESS ]   TFDP2 [ SEEK ]   TFDP2 [ MEM ]
Gene Expression Viewer (FireBrowse)TFDP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7029
GTEX Portal (Tissue expression)TFDP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14188   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14188  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14188
Splice isoforms : SwissVarQ14188
PhosPhoSitePlusQ14188
Domains : Interpro (EBI)DP-2    E2F_WHTH_DNA-bd_dom    Transc_factor_DP_C    Transcrpt_fac_DP    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)DP (PF08781)    E2F_TDP (PF02319)   
Domain families : Pfam (NCBI)pfam08781    pfam02319   
Domain families : Smart (EMBL)DP (SM01138)  E2F_TDP (SM01372)  
Conserved Domain (NCBI)TFDP2
DMDM Disease mutations7029
Blocks (Seattle)TFDP2
PDB (SRS)1CF7   
PDB (PDBSum)1CF7   
PDB (IMB)1CF7   
PDB (RSDB)1CF7   
Structural Biology KnowledgeBase1CF7   
SCOP (Structural Classification of Proteins)1CF7   
CATH (Classification of proteins structures)1CF7   
SuperfamilyQ14188
Human Protein AtlasENSG00000114126
Peptide AtlasQ14188
HPRD03696
IPIIPI00029096   IPI00296752   IPI00218877   IPI00295550   IPI00915033   IPI00982683   IPI00953655   IPI00944999   IPI00945078   IPI00946984   IPI00945493   IPI00794050   IPI00984927   IPI00946020   IPI00947391   IPI00795123   IPI00946333   
Protein Interaction databases
DIP (DOE-UCLA)Q14188
IntAct (EBI)Q14188
FunCoupENSG00000114126
BioGRIDTFDP2
STRING (EMBL)TFDP2
ZODIACTFDP2
Ontologies - Pathways
QuickGOQ14188
Ontology : AmiGORNA polymerase II transcription factor activity, sequence-specific DNA binding  DNA binding  transcription factor activity, sequence-specific DNA binding  transcription cofactor activity  protein binding  nucleus  nucleoplasm  transcription factor complex  mitochondrion  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  heart development  transcription factor binding  protein domain specific binding  negative regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway  
Ontology : EGO-EBIRNA polymerase II transcription factor activity, sequence-specific DNA binding  DNA binding  transcription factor activity, sequence-specific DNA binding  transcription cofactor activity  protein binding  nucleus  nucleoplasm  transcription factor complex  mitochondrion  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  heart development  transcription factor binding  protein domain specific binding  negative regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway  
Pathways : KEGGCell cycle   
NDEx NetworkTFDP2
Atlas of Cancer Signalling NetworkTFDP2
Wikipedia pathwaysTFDP2
Orthology - Evolution
OrthoDB7029
GeneTree (enSembl)ENSG00000114126
Phylogenetic Trees/Animal Genes : TreeFamTFDP2
HOVERGENQ14188
HOGENOMQ14188
Homologs : HomoloGeneTFDP2
Homology/Alignments : Family Browser (UCSC)TFDP2
Gene fusions - Rearrangements
Fusion : MitelmanLANCL2/TFDP2 [7p11.2/3q23]  [t(3;7)(q23;p11)]  
Fusion : MitelmanTFDP2/LANCL2 [3q23/7p11.2]  [t(3;7)(q23;p11)]  
Fusion : MitelmanTFDP2/PLD1 [3q23/3q26.31]  [t(3;3)(q23;q26)]  
Fusion: TCGALANCL2 7p11.2 TFDP2 3q23 BRCA
Fusion: TCGAPLS1 3q23 TFDP2 3q23 LUSC
Fusion: TCGATFDP2 3q23 COG5 7q22.3 HNSC
Fusion: TCGATFDP2 3q23 GK5 3q23 LGG
Fusion: TCGATFDP2 3q23 LANCL2 7p11.2 BRCA
Fusion: TCGATFDP2 3q23 PLD1 3q26.31 BRCA
Fusion Cancer (Beijing)TFDP2 [3q23]  -  ZNF721 [4p16.3]  [FUSC000509]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTFDP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TFDP2
dbVarTFDP2
ClinVarTFDP2
1000_GenomesTFDP2 
Exome Variant ServerTFDP2
ExAC (Exome Aggregation Consortium)TFDP2 (select the gene name)
Genetic variants : HAPMAP7029
Genomic Variants (DGV)TFDP2 [DGVbeta]
DECIPHERTFDP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTFDP2 
Mutations
ICGC Data PortalTFDP2 
TCGA Data PortalTFDP2 
Broad Tumor PortalTFDP2
OASIS PortalTFDP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTFDP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTFDP2
intOGen PortalTFDP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TFDP2
DgiDB (Drug Gene Interaction Database)TFDP2
DoCM (Curated mutations)TFDP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TFDP2 (select a term)
intoGenTFDP2
Cancer3DTFDP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602160   
Orphanet
MedgenTFDP2
Genetic Testing Registry TFDP2
NextProtQ14188 [Medical]
TSGene7029
GENETestsTFDP2
Target ValidationTFDP2
Huge Navigator TFDP2 [HugePedia]
snp3D : Map Gene to Disease7029
BioCentury BCIQTFDP2
ClinGenTFDP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7029
Chemical/Pharm GKB GenePA36466
Clinical trialTFDP2
Miscellaneous
canSAR (ICR)TFDP2 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTFDP2
EVEXTFDP2
GoPubMedTFDP2
iHOPTFDP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:59:09 CEST 2017
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