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TFEC (transcription factor EC)

Identity

Alias (NCBI)TCFEC
TFE-C
TFEC-L
TFECL
bHLHe34
hTFEC-L
HGNC (Hugo) TFEC
HGNC Alias symbTCFEC
TFECL
bHLHe34
LocusID (NCBI) 22797
Atlas_Id 42531
Location 7q31.2  [Link to chromosome band 7q31]
Location_base_pair Starts at 115935153 and ends at 116030763 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CAPZA2 (7q31.2)::TFEC (7q31.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TFEC   11754
Cards
Entrez_Gene (NCBI)TFEC    transcription factor EC
AliasesTCFEC; TFE-C; TFEC-L; TFECL; 
bHLHe34; hTFEC-L
GeneCards (Weizmann)TFEC
Ensembl hg19 (Hinxton)ENSG00000105967 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105967 [Gene_View]  ENSG00000105967 [Sequence]  chr7:115935153-116030763 [Contig_View]  TFEC [Vega]
ICGC DataPortalENSG00000105967
TCGA cBioPortalTFEC
AceView (NCBI)TFEC
Genatlas (Paris)TFEC
SOURCE (Princeton)TFEC
Genetics Home Reference (NIH)TFEC
Genomic and cartography
GoldenPath hg38 (UCSC)TFEC  -     chr7:115935153-116030763 -  7q31.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TFEC  -     7q31.2   [Description]    (hg19-Feb_2009)
GoldenPathTFEC - 7q31.2 [CytoView hg19]  TFEC - 7q31.2 [CytoView hg38]
ImmunoBaseENSG00000105967
Genome Data Viewer NCBITFEC [Mapview hg19]  
OMIM604732   
Gene and transcription
Genbank (Entrez)AJ608795 AK301479 AK313546 BC029891 BX538223
RefSeq transcript (Entrez)NM_001018058 NM_001244583 NM_012252
Consensus coding sequences : CCDS (NCBI)TFEC
Gene ExpressionTFEC [ NCBI-GEO ]   TFEC [ EBI - ARRAY_EXPRESS ]   TFEC [ SEEK ]   TFEC [ MEM ]
Gene Expression Viewer (FireBrowse)TFEC [ Firebrowse - Broad ]
GenevisibleExpression of TFEC in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22797
GTEX Portal (Tissue expression)TFEC
Human Protein AtlasENSG00000105967-TFEC [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14948   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14948  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14948
PhosPhoSitePlusO14948
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom    HLH_DNA-bd_sf    MiT/TFE_C    TFEC   
Domain families : Pfam (Sanger)DUF3371 (PF11851)    HLH (PF00010)   
Domain families : Pfam (NCBI)pfam11851    pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)TFEC
SuperfamilyO14948
AlphaFold pdb e-kbO14948   
Human Protein Atlas [tissue]ENSG00000105967-TFEC [tissue]
HPRD05294
Protein Interaction databases
DIP (DOE-UCLA)O14948
IntAct (EBI)O14948
BioGRIDTFEC
STRING (EMBL)TFEC
ZODIACTFEC
Ontologies - Pathways
QuickGOO14948
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  chromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  protein binding  nucleus  nucleoplasm  regulation of transcription by RNA polymerase II  cellular response to heat  positive regulation of transcription by RNA polymerase II  protein dimerization activity  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  chromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  protein binding  nucleus  nucleoplasm  regulation of transcription by RNA polymerase II  cellular response to heat  positive regulation of transcription by RNA polymerase II  protein dimerization activity  sequence-specific double-stranded DNA binding  
NDEx NetworkTFEC
Atlas of Cancer Signalling NetworkTFEC
Wikipedia pathwaysTFEC
Orthology - Evolution
OrthoDB22797
GeneTree (enSembl)ENSG00000105967
Phylogenetic Trees/Animal Genes : TreeFamTFEC
Homologs : HomoloGeneTFEC
Homology/Alignments : Family Browser (UCSC)TFEC
Gene fusions - Rearrangements
Fusion : QuiverTFEC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTFEC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TFEC
dbVarTFEC
ClinVarTFEC
MonarchTFEC
1000_GenomesTFEC 
Exome Variant ServerTFEC
GNOMAD BrowserENSG00000105967
Varsome BrowserTFEC
ACMGTFEC variants
VarityO14948
Genomic Variants (DGV)TFEC [DGVbeta]
DECIPHERTFEC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTFEC 
Mutations
ICGC Data PortalTFEC 
TCGA Data PortalTFEC 
Broad Tumor PortalTFEC
OASIS PortalTFEC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTFEC  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTFEC
Mutations and Diseases : HGMDTFEC
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTFEC
DgiDB (Drug Gene Interaction Database)TFEC
DoCM (Curated mutations)TFEC
CIViC (Clinical Interpretations of Variants in Cancer)TFEC
Cancer3DTFEC
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604732   
Orphanet
DisGeNETTFEC
MedgenTFEC
Genetic Testing Registry TFEC
NextProtO14948 [Medical]
GENETestsTFEC
Target ValidationTFEC
Huge Navigator TFEC [HugePedia]
ClinGenTFEC
Clinical trials, drugs, therapy
MyCancerGenomeTFEC
Protein Interactions : CTDTFEC
Pharm GKB GenePA36469
PharosO14948
Clinical trialTFEC
Miscellaneous
canSAR (ICR)TFEC
HarmonizomeTFEC
ARCHS4TFEC
DataMed IndexTFEC
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTFEC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Jan 20 13:02:39 CET 2022

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