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TFEC (transcription factor EC)

Identity

Other namesTCFEC
TFE-C
TFEC-L
TFECL
bHLHe34
hTFEC-L
HGNC (Hugo) TFEC
LocusID (NCBI) 22797
Location 7q31.2
Location_base_pair Starts at 115575202 and ends at 115670867 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas)

Solid Tumors AmeloblastomID5945 MedulloblastomaID5065 rhab5004

External links

Nomenclature
HGNC (Hugo)TFEC   11754
Cards
Entrez_Gene (NCBI)TFEC  22797  transcription factor EC
GeneCards (Weizmann)TFEC
Ensembl hg19 (Hinxton)ENSG00000105967 [Gene_View]  chr7:115575202-115670867 [Contig_View]  TFEC [Vega]
Ensembl hg38 (Hinxton)ENSG00000105967 [Gene_View]  chr7:115575202-115670867 [Contig_View]  TFEC [Vega]
ICGC DataPortalENSG00000105967
cBioPortalTFEC
AceView (NCBI)TFEC
Genatlas (Paris)TFEC
WikiGenes22797
SOURCE (Princeton)TFEC
Genomic and cartography
GoldenPath hg19 (UCSC)TFEC  -     chr7:115575202-115670867 -  7q31.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TFEC  -     7q31.2   [Description]    (hg38-Dec_2013)
EnsemblTFEC - 7q31.2 [CytoView hg19]  TFEC - 7q31.2 [CytoView hg38]
Mapping of homologs : NCBITFEC [Mapview hg19]  TFEC [Mapview hg38]
OMIM604732   
Gene and transcription
Genbank (Entrez)AJ608795 AK301479 AK313546 BC029891 BX538223
RefSeq transcript (Entrez)NM_001018058 NM_001244583 NM_012252
RefSeq genomic (Entrez)AC_000139 NC_000007 NC_018918 NG_030005 NT_007933 NW_001839071 NW_004929332
Consensus coding sequences : CCDS (NCBI)TFEC
Cluster EST : UnigeneHs.125962 [ NCBI ]
CGAP (NCI)Hs.125962
Alternative Splicing : Fast-db (Paris)GSHG0028510
Alternative Splicing GalleryENSG00000105967
Gene ExpressionTFEC [ NCBI-GEO ]     TFEC [ SEEK ]   TFEC [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14948 (Uniprot)
NextProtO14948  [Medical]
With graphics : InterProO14948
Splice isoforms : SwissVarO14948 (Swissvar)
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom    bHLH_ZIP_TF_MiT/TFE    TFEC   
Related proteins : CluSTrO14948
Domain families : Pfam (Sanger)DUF3371 (PF11851)    HLH (PF00010)   
Domain families : Pfam (NCBI)pfam11851    pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
DMDM Disease mutations22797
Blocks (Seattle)O14948
Human Protein AtlasENSG00000105967
Peptide AtlasO14948
HPRD05294
IPIIPI00016824   IPI00852594   IPI00167022   IPI00878954   IPI00657986   IPI00946731   
Protein Interaction databases
DIP (DOE-UCLA)O14948
IntAct (EBI)O14948
FunCoupENSG00000105967
BioGRIDTFEC
IntegromeDBTFEC
STRING (EMBL)TFEC
Ontologies - Pathways
QuickGOO14948
Ontology : AmiGODNA binding  sequence-specific DNA binding transcription factor activity  transcription coactivator activity  transcription corepressor activity  nucleus  nucleolus  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  cellular response to heat  protein dimerization activity  
Ontology : EGO-EBIDNA binding  sequence-specific DNA binding transcription factor activity  transcription coactivator activity  transcription corepressor activity  nucleus  nucleolus  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  cellular response to heat  protein dimerization activity  
Protein Interaction DatabaseTFEC
DoCM (Curated mutations)TFEC
Wikipedia pathwaysTFEC
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerTFEC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TFEC
dbVarTFEC
ClinVarTFEC
1000_GenomesTFEC 
Exome Variant ServerTFEC
SNP (GeneSNP Utah)TFEC
SNP : HGBaseTFEC
Genetic variants : HAPMAPTFEC
Genomic VariantsTFEC  TFEC [DGVbeta]
Mutations
ICGC Data PortalENSG00000105967 
Somatic Mutations in Cancer : COSMICTFEC 
CONAN: Copy Number AnalysisTFEC 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)7:115575202-115670867
Mutations and Diseases : HGMDTFEC
OMIM604732   
MedgenTFEC
NextProtO14948 [Medical]
GENETestsTFEC
Disease Genetic AssociationTFEC
Huge Navigator TFEC [HugePedia]  TFEC [HugeCancerGEM]
snp3D : Map Gene to Disease22797
DGIdb (Drug Gene Interaction db)TFEC
General knowledge
Homologs : HomoloGeneTFEC
Homology/Alignments : Family Browser (UCSC)TFEC
Phylogenetic Trees/Animal Genes : TreeFamTFEC
Chemical/Protein Interactions : CTD22797
Chemical/Pharm GKB GenePA36469
Clinical trialTFEC
Cancer Resource (Charite)ENSG00000105967
Other databases
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
CoreMineTFEC
GoPubMedTFEC
iHOPTFEC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 01:53:49 CET 2014

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