TFIP11 (tuftelin interacting protein 11)

2016-01-01  

Identity

HGNC
TFIP11
LOCATION
22q12.1
LOCUSID
24144
ALIAS
NTR1,STIP,STIP-1,Spp382,TIP39,bK445C9.6
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 24144
MIM: 612747
HGNC: 17165
Ensembl: ENSG00000100109

Variants:

dbSNP: 24144
ClinVar: 24144
TCGA: ENSG00000100109
COSMIC: TFIP11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100109ENST00000405938Q9UBB9
ENSG00000100109ENST00000405938A0A024R1I7
ENSG00000100109ENST00000407148Q9UBB9
ENSG00000100109ENST00000407148A0A024R1I7
ENSG00000100109ENST00000407431Q9UBB9
ENSG00000100109ENST00000407431A0A024R1I7
ENSG00000100109ENST00000407690Q9UBB9
ENSG00000100109ENST00000407690A0A024R1I7
ENSG00000100109ENST00000418876F6SQZ1
ENSG00000100109ENST00000420242F6UKU9
ENSG00000100109ENST00000440258F6UQ07
ENSG00000100109ENST00000450493H0Y4U8
ENSG00000100109ENST00000455080F6XM96
ENSG00000100109ENST00000619735Q9UBB9
ENSG00000100109ENST00000619735A0A024R1I7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163

References

Pubmed IDYearTitleCitations
187810682008Enamel formation genes are associated with high caries experience in Turkish children.41
190860532009Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.34
203989082010Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.32
237905032013Genes expressed in dental enamel development are associated with molar-incisor hypomineralization.21
158681022005Structural organization and cellular localization of tuftelin-interacting protein 11 (TFIP11).17
198574622009Identification of a novel nuclear localization signal and speckle-targeting sequence of tuftelin-interacting protein 11, a splicing factor involved in spliceosome disassembly.12
253736992015Effects of enamel matrix genes on dental caries are moderated by fluoride exposures.12
263548522015STIP overexpression confers oncogenic potential to human non-small cell lung cancer cells by regulating cell cycle and apoptosis.4
264606172015STIP is a critical nuclear scaffolding protein linking USP7 to p53-Mdm2 pathway regulation.4
277587122016STIP Regulates ERK1/2 Signaling Pathway Involved in Interaction with PP1γ in Lymphoblastic Leukemia.0

Citation

Dessen P

TFIP11 (tuftelin interacting protein 11)

Atlas Genet Cytogenet Oncol Haematol. 2016-01-01

Online version: http://atlasgeneticsoncology.org/gene/55589/tfip11