Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TFR2 (transferrin receptor 2)

Identity

Other namesHFE3
TFRC2
HGNC (Hugo) TFR2
LocusID (NCBI) 7036
Location 7q22.1
Location_base_pair Starts at 100218039 and ends at 100231273 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)TFR2   11762
Entrez_Gene (NCBI)TFR2  7036  transferrin receptor 2
Cards
GeneCards (Weizmann)TFR2
Ensembl (Hinxton)ENSG00000106327 [Gene_View]  chr7:100218039-100231273 [Contig_View]  TFR2 [Vega]
AceView (NCBI)TFR2
Genatlas (Paris)TFR2
SOURCE (Stanford)NM_001206855 NM_003227
Genomic and cartography
GoldenPath (UCSC)TFR2  -  7q22.1   chr7:100218039-100231273 -  7q22.1   [Description]    (hg19-Feb_2009)
EnsemblTFR2 - 7q22.1 [CytoView]
Mapping of homologs : NCBITFR2 [Mapview]
OMIM604250   604720   
Gene and transcription
Genbank (Entrez)AF067864 AF085928 AK000421 AK022002 BC142630
RefSeq transcript (SRS)NM_001206855 NM_003227
RefSeq transcript (Entrez)NM_001206855 NM_003227
RefSeq genomic (SRS)AC_000068 AC_000139 NC_000007 NC_018918 NG_007989 NT_007933 NT_079595 NW_001839065 NW_004078032
RefSeq genomic (Entrez)AC_000068 AC_000139 NC_000007 NC_018918 NG_007989 NT_007933 NT_079595 NW_001839065 NW_004078032
Consensus coding sequences : CCDS (NCBI)TFR2
Cluster EST : UnigeneHs.544932 [ SRS ] Hs.544932 [ NCBI ]
CGAP (NCI)Hs.544932
Alternative Splicing : Fast-db (Paris)GSHG0028418
Alternative Splicing GalleryENSG00000106327
Gene ExpressionTFR2 [ NCBI-GEO ]   TFR2 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UP52 (SRS) Q9UP52 (Uniprot)
NextProtQ9UP52
With graphics : InterProQ9UP52
Splice isoforms : SwissVarQ9UP52(Swissvar)
Domains : Interpro (SRS)Peptidase_M28    Protease-assoc_domain    TFR-like_dimer_dom   
Domains : Interpro (EBI)Peptidase_M28    Protease-assoc_domain    TFR-like_dimer_dom   
Related proteins : CluSTrQ9UP52
Domain families : Pfam (SRS)PA (PF02225)    Peptidase_M28 (PF04389)    TFR_dimer (PF04253)   
Domain families : Pfam (Sanger)PA (PF02225)    Peptidase_M28 (PF04389)    TFR_dimer (PF04253)   
Domain families : Pfam (NCBI)pfam02225    pfam04389    pfam04253   
DMDM7036
Blocks (Seattle)Q9UP52
Human Protein AtlasENSG00000106327
HPRD05282
IPIIPI00215612   IPI00219900   IPI00219901   IPI00855864   IPI00946487   
Protein Interaction databases
DIP (DOE-UCLA)Q9UP52
IntAct (EBI)Q9UP52
FunCoupENSG00000106327
REACTOMETFR2
Protein Interaction Database7036
BioGRIDTFR2
InParanoidQ9UP52
Interologous Interaction database Q9UP52
IntegromeDBTFR2
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TFR2
SNP (GeneSNP Utah)TFR2
SNP : HGBaseTFR2
Genetic variants : HAPMAPTFR2
Somatic Mutations in Cancer : COSMICTFR2 
CONAN: Copy Number AnalysisTFR2 
Mutations and Diseases : HGMDTFR2
OMIM604250    604720   
GENETests604250    604720   
Disease Genetic AssociationTFR2
Huge Navigator TFR2 [HugePedia]  TFR2 [HugeCancerGEM]
Genomic VariantsTFR2  TFR2 [DGVbeta]
snp3D : Map Gene to Disease7036
General knowledge
Homologs : HomoloGeneTFR2
Homology/Alignments : Family Browser (UCSC)TFR2
Phylogenetic Trees/Animal Genes : TreeFamTFR2
Chemical/Protein Interactions : CTD7036
Chemical/Pharm GKB GenePA36477
Clinical trialTFR2
Cancer Resource (Charite)ENSG00000106327
Ontology : AmiGOtransferrin receptor activity  cytoplasm  integral to plasma membrane  proteolysis  iron ion transport  cellular iron ion homeostasis  peptidase activity  
Ontology : EGO-EBItransferrin receptor activity  cytoplasm  integral to plasma membrane  proteolysis  iron ion transport  cellular iron ion homeostasis  peptidase activity  
Other databases
Probes
Litterature
PubMed83 Pubmed reference(s) in Entrez
PubGeneTFR2
iHOPTFR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:27:13 CEST 2013
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