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TG (thyroglobulin)

Identity

Other namesAITD3
TGN
HGNC (Hugo) TG
LocusID (NCBI) 7038
Atlas_Id 46096
Location 8q24.22
Location_base_pair Starts at 133879205 and ends at 134147143 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ANP32B (9q22.33) / TG (8q24.22)HIRA (22q11.21) / TG (8q24.22)MALAT1 (11q13.1) / TG (8q24.22)
NOL3 (16q22.1) / TG (8q24.22)SDHAF1 (19q13.12) / TG (8q24.22)TG (8q24.22) / CTNNB1 (3p22.1)
TG (8q24.22) / FNBP1 (9q34.11)TG (8q24.22) / GPRC5A (12p13.1)TG (8q24.22) / ITGAX (16p11.2)
TG (8q24.22) / PFKP (10p15.2)TG (8q24.22) / SDHAF1 (19q13.12)TG (8q24.22) / TG (8q24.22)
TG (8q24.22) / THADA (2p21)TG (8q24.22) / TNRC6A (16p12.1)TG (8q24.22) / USP19 (3p21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TG   11764
Cards
Entrez_Gene (NCBI)TG  7038  thyroglobulin
AliasesAITD3; TGN
GeneCards (Weizmann)TG
Ensembl hg19 (Hinxton)ENSG00000042832 [Gene_View]  chr8:133879205-134147143 [Contig_View]  TG [Vega]
Ensembl hg38 (Hinxton)ENSG00000042832 [Gene_View]  chr8:133879205-134147143 [Contig_View]  TG [Vega]
ICGC DataPortalENSG00000042832
TCGA cBioPortalTG
AceView (NCBI)TG
Genatlas (Paris)TG
WikiGenes7038
SOURCE (Princeton)TG
Genomic and cartography
GoldenPath hg19 (UCSC)TG  -     chr8:133879205-134147143 +  8q24.22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TG  -     8q24.22   [Description]    (hg38-Dec_2013)
EnsemblTG - 8q24.22 [CytoView hg19]  TG - 8q24.22 [CytoView hg38]
Mapping of homologs : NCBITG [Mapview hg19]  TG [Mapview hg38]
OMIM188450   274700   608175   
Gene and transcription
Genbank (Entrez)AB209159 AK299197 AK303666 AK303667 AU141420
RefSeq transcript (Entrez)NM_003235
RefSeq genomic (Entrez)NC_000008 NC_018919 NG_015832 NT_008046 NW_004929340
Consensus coding sequences : CCDS (NCBI)TG
Cluster EST : UnigeneHs.654591 [ NCBI ]
CGAP (NCI)Hs.654591
Alternative Splicing GalleryENSG00000042832
Gene ExpressionTG [ NCBI-GEO ]   TG [ EBI - ARRAY_EXPRESS ]   TG [ SEEK ]   TG [ MEM ]
Gene Expression Viewer (FireBrowse)TG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7038
GTEX Portal (Tissue expression)TG
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01266 (Uniprot)
NextProtP01266  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP01266
Splice isoforms : SwissVarP01266 (Swissvar)
PhosPhoSitePlusP01266
Domaine pattern : Prosite (Expaxy)CARBOXYLESTERASE_B_2 (PS00941)    THYROGLOBULIN_1_1 (PS00484)    THYROGLOBULIN_1_2 (PS51162)   
Domains : Interpro (EBI)AB_hydrolase    CarbesteraseB    Carboxylesterase_B_CS    Thyroglobulin    Thyroglobulin_1    Tyr-kin_ephrin_A/B_rcpt-like   
Domain families : Pfam (Sanger)COesterase (PF00135)    GCC2_GCC3 (PF07699)    Thyroglobulin_1 (PF00086)   
Domain families : Pfam (NCBI)pfam00135    pfam07699    pfam00086   
Domain families : Smart (EMBL)TY (SM00211)  
DMDM Disease mutations7038
Blocks (Seattle)TG
SuperfamilyP01266
Human Protein AtlasENSG00000042832
Peptide AtlasP01266
HPRD01782
IPIIPI00306129   IPI00549199   IPI00976276   IPI01009769   IPI01011257   IPI00985038   IPI00983747   IPI00984393   IPI00982315   IPI00978610   IPI00978965   IPI00982973   
Protein Interaction databases
DIP (DOE-UCLA)P01266
IntAct (EBI)P01266
FunCoupENSG00000042832
BioGRIDTG
STRING (EMBL)TG
ZODIACTG
Ontologies - Pathways
QuickGOP01266
Ontology : AmiGOhormone activity  extracellular region  extracellular space  endoplasmic reticulum  Golgi apparatus  thyroid hormone generation  signal transduction  response to pH  iodide transport  thyroid gland development  regulation of myelination  protein complex binding  response to lipopolysaccharide  hormone biosynthetic process  protein homodimerization activity  anion binding  protein complex  transcytosis  perinuclear region of cytoplasm  chaperone binding  carboxylic ester hydrolase activity  
Ontology : EGO-EBIhormone activity  extracellular region  extracellular space  endoplasmic reticulum  Golgi apparatus  thyroid hormone generation  signal transduction  response to pH  iodide transport  thyroid gland development  regulation of myelination  protein complex binding  response to lipopolysaccharide  hormone biosynthetic process  protein homodimerization activity  anion binding  protein complex  transcytosis  perinuclear region of cytoplasm  chaperone binding  carboxylic ester hydrolase activity  
Pathways : KEGGThyroid hormone synthesis    Autoimmune thyroid disease   
NDEx Network
Atlas of Cancer Signalling NetworkTG
Wikipedia pathwaysTG
Orthology - Evolution
OrthoDB7038
GeneTree (enSembl)ENSG00000042832
Phylogenetic Trees/Animal Genes : TreeFamTG
Homologs : HomoloGeneTG
Homology/Alignments : Family Browser (UCSC)TG
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerTG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TG
dbVarTG
ClinVarTG
1000_GenomesTG 
Exome Variant ServerTG
ExAC (Exome Aggregation Consortium)TG (select the gene name)
Genetic variants : HAPMAP7038
Genomic Variants (DGV)TG [DGVbeta]
Mutations
ICGC Data PortalTG 
TCGA Data PortalTG 
Broad Tumor PortalTG
OASIS PortalTG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTG 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TG
DgiDB (Drug Gene Interaction Database)TG
DoCM (Curated mutations)TG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TG (select a term)
intoGenTG
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)8:133879205-134147143  ENSG00000042832
CONAN: Copy Number AnalysisTG 
Mutations and Diseases : HGMDTG
OMIM188450    274700    608175   
MedgenTG
Genetic Testing Registry TG
NextProtP01266 [Medical]
TSGene7038
GENETestsTG
Huge Navigator TG [HugePedia]
snp3D : Map Gene to Disease7038
BioCentury BCIQTG
ClinGenTG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7038
Chemical/Pharm GKB GenePA36479
Clinical trialTG
Miscellaneous
canSAR (ICR)TG (select the gene name)
Probes
Litterature
PubMed154 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTG
EVEXTG
GoPubMedTG
iHOPTG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat May 28 11:24:14 CEST 2016

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