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TG (thyroglobulin)

Identity

Alias (NCBI)AITD3
TGN
HGNC (Hugo) TG
HGNC Alias symbTGN
AITD3
LocusID (NCBI) 7038
Atlas_Id 46096
Location 8q24.22  [Link to chromosome band 8q24]
Location_base_pair Starts at 132866958 and ends at 133134899 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANP32B (9q22.33) / TG (8q24.22)HIRA (22q11.21) / TG (8q24.22)MALAT1 (11q13.1) / TG (8q24.22)
NOL3 (16q22.1) / TG (8q24.22)SDHAF1 (19q13.12) / TG (8q24.22)TG (8q24.22) / CTNNB1 (3p22.1)
TG (8q24.22) / FNBP1 (9q34.11)TG (8q24.22) / GPRC5A (12p13.1)TG (8q24.22) / ITGAX (16p11.2)
TG (8q24.22) / PFKP (10p15.2)TG (8q24.22) / SDHAF1 (19q13.12)TG (8q24.22) / TG (8q24.22)
TG (8q24.22) / THADA (2p21)TG (8q24.22) / TNRC6A (16p12.1)TG (8q24.22) / USP19 (3p21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TG   11764
Cards
Entrez_Gene (NCBI)TG    thyroglobulin
AliasesAITD3; TGN
GeneCards (Weizmann)TG
Ensembl hg19 (Hinxton)ENSG00000042832 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000042832 [Gene_View]  ENSG00000042832 [Sequence]  chr8:132866958-133134899 [Contig_View]  TG [Vega]
ICGC DataPortalENSG00000042832
TCGA cBioPortalTG
AceView (NCBI)TG
Genatlas (Paris)TG
SOURCE (Princeton)TG
Genetics Home Reference (NIH)TG
Genomic and cartography
GoldenPath hg38 (UCSC)TG  -     chr8:132866958-133134899 +  8q24.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TG  -     8q24.22   [Description]    (hg19-Feb_2009)
GoldenPathTG - 8q24.22 [CytoView hg19]  TG - 8q24.22 [CytoView hg38]
ImmunoBaseENSG00000042832
Genome Data Viewer NCBITG [Mapview hg19]  
OMIM188450   274700   608175   
Gene and transcription
Genbank (Entrez)AB209159 AK299197 AK303666 AK303667 AU141420
RefSeq transcript (Entrez)NM_003235
Consensus coding sequences : CCDS (NCBI)TG
Gene ExpressionTG [ NCBI-GEO ]   TG [ EBI - ARRAY_EXPRESS ]   TG [ SEEK ]   TG [ MEM ]
Gene Expression Viewer (FireBrowse)TG [ Firebrowse - Broad ]
GenevisibleExpression of TG in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7038
GTEX Portal (Tissue expression)TG
Human Protein AtlasENSG00000042832-TG [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01266   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP01266  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP01266
PhosPhoSitePlusP01266
Domaine pattern : Prosite (Expaxy)CARBOXYLESTERASE_B_2 (PS00941)    THYROGLOBULIN_1_1 (PS00484)    THYROGLOBULIN_1_2 (PS51162)   
Domains : Interpro (EBI)AB_hydrolase    CarbesteraseB    Carboxylesterase_B_CS    Thyroglobulin    Thyroglobulin_1    Thyroglobulin_1_sf    Tyr-kin_ephrin_A/B_rcpt-like   
Domain families : Pfam (Sanger)COesterase (PF00135)    Ephrin_rec_like (PF07699)    Thyroglobulin_1 (PF00086)   
Domain families : Pfam (NCBI)pfam00135    pfam07699    pfam00086   
Domain families : Smart (EMBL)Ephrin_rec_like (SM01411)  TY (SM00211)  
Conserved Domain (NCBI)TG
PDB (RSDB)6SCJ   
PDB Europe6SCJ   
PDB (PDBSum)6SCJ   
PDB (IMB)6SCJ   
Structural Biology KnowledgeBase6SCJ   
SCOP (Structural Classification of Proteins)6SCJ   
CATH (Classification of proteins structures)6SCJ   
SuperfamilyP01266
AlphaFold pdb e-kbP01266   
Human Protein Atlas [tissue]ENSG00000042832-TG [tissue]
HPRD01782
Protein Interaction databases
DIP (DOE-UCLA)P01266
IntAct (EBI)P01266
BioGRIDTG
STRING (EMBL)TG
ZODIACTG
Ontologies - Pathways
QuickGOP01266
Ontology : AmiGOhormone activity  protein binding  extracellular region  extracellular space  extracellular space  thyroid hormone generation  thyroid hormone generation  thyroid hormone generation  signal transduction  iodide transport  thyroid gland development  regulation of myelination  hormone biosynthetic process  identical protein binding  
Ontology : EGO-EBIhormone activity  protein binding  extracellular region  extracellular space  extracellular space  thyroid hormone generation  thyroid hormone generation  thyroid hormone generation  signal transduction  iodide transport  thyroid gland development  regulation of myelination  hormone biosynthetic process  identical protein binding  
Pathways : KEGGThyroid hormone synthesis    Autoimmune thyroid disease   
NDEx NetworkTG
Atlas of Cancer Signalling NetworkTG
Wikipedia pathwaysTG
Orthology - Evolution
OrthoDB7038
GeneTree (enSembl)ENSG00000042832
Phylogenetic Trees/Animal Genes : TreeFamTG
Homologs : HomoloGeneTG
Homology/Alignments : Family Browser (UCSC)TG
Gene fusions - Rearrangements
Fusion : MitelmanTG/THADA [8q24.22/2p21]  
Fusion : QuiverTG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TG
dbVarTG
ClinVarTG
MonarchTG
1000_GenomesTG 
Exome Variant ServerTG
GNOMAD BrowserENSG00000042832
Varsome BrowserTG
ACMGTG variants
VarityP01266
Genomic Variants (DGV)TG [DGVbeta]
DECIPHERTG [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTG 
Mutations
ICGC Data PortalTG 
TCGA Data PortalTG 
Broad Tumor PortalTG
OASIS PortalTG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTG  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTG
Mutations and Diseases : HGMDTG
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTG
DgiDB (Drug Gene Interaction Database)TG
DoCM (Curated mutations)TG
CIViC (Clinical Interpretations of Variants in Cancer)TG
Cancer3DTG
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM188450    274700    608175   
Orphanet12671   
DisGeNETTG
MedgenTG
Genetic Testing Registry TG
NextProtP01266 [Medical]
GENETestsTG
Target ValidationTG
Huge Navigator TG [HugePedia]
ClinGenTG
Clinical trials, drugs, therapy
MyCancerGenomeTG
Protein Interactions : CTDTG
Pharm GKB GenePA36479
PharosP01266
Clinical trialTG
Miscellaneous
canSAR (ICR)TG
HarmonizomeTG
DataMed IndexTG
Probes
Litterature
PubMed189 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:34:54 CEST 2021

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