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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

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TG (thyroglobulin)

Identity

Other namesAITD3
TGN
HGNC (Hugo) TG
LocusID (NCBI) 7038
Location 8q24.22
Location_base_pair Starts at 133879205 and ends at 134147143 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TG   11764
Cards
Entrez_Gene (NCBI)TG  7038  thyroglobulin
GeneCards (Weizmann)TG
Ensembl hg19 (Hinxton)ENSG00000042832 [Gene_View]  chr8:133879205-134147143 [Contig_View]  TG [Vega]
Ensembl hg38 (Hinxton)ENSG00000042832 [Gene_View]  chr8:133879205-134147143 [Contig_View]  TG [Vega]
ICGC DataPortalENSG00000042832
cBioPortalTG
AceView (NCBI)TG
Genatlas (Paris)TG
WikiGenes7038
SOURCE (Princeton)TG
Genomic and cartography
GoldenPath hg19 (UCSC)TG  -     chr8:133879205-134147143 +  8q24.22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TG  -     8q24.22   [Description]    (hg38-Dec_2013)
EnsemblTG - 8q24.22 [CytoView hg19]  TG - 8q24.22 [CytoView hg38]
Mapping of homologs : NCBITG [Mapview hg19]  TG [Mapview hg38]
OMIM188450   274700   608175   
Gene and transcription
Genbank (Entrez)AB209159 AK299197 AK303666 AK303667 AU141420
RefSeq transcript (Entrez)NM_003235
RefSeq genomic (Entrez)AC_000140 NC_000008 NC_018919 NG_015832 NT_008046 NW_001839138 NW_004929340
Consensus coding sequences : CCDS (NCBI)TG
Cluster EST : UnigeneHs.654591 [ NCBI ]
CGAP (NCI)Hs.654591
Alternative Splicing : Fast-db (Paris)GSHG0029260
Alternative Splicing GalleryENSG00000042832
Gene ExpressionTG [ NCBI-GEO ]     TG [ SEEK ]   TG [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01266 (Uniprot)
NextProtP01266  [Medical]
With graphics : InterProP01266
Splice isoforms : SwissVarP01266 (Swissvar)
Domaine pattern : Prosite (Expaxy)CARBOXYLESTERASE_B_2 (PS00941)    THYROGLOBULIN_1_1 (PS00484)    THYROGLOBULIN_1_2 (PS51162)   
Domains : Interpro (EBI)AB_hydrolase    CarbesteraseB    Carboxylesterase_B_CS    Thyroglobulin    Thyroglobulin_1    Tyr-kin_ephrin_A/B_rcpt-like   
Related proteins : CluSTrP01266
Domain families : Pfam (Sanger)COesterase (PF00135)    GCC2_GCC3 (PF07699)    Thyroglobulin_1 (PF00086)   
Domain families : Pfam (NCBI)pfam00135    pfam07699    pfam00086   
Domain families : Smart (EMBL)TY (SM00211)  
DMDM Disease mutations7038
Blocks (Seattle)P01266
Human Protein AtlasENSG00000042832
Peptide AtlasP01266
HPRD01782
IPIIPI00306129   IPI00549199   IPI00976276   IPI01009769   IPI01011257   IPI00985038   IPI00983747   IPI00984393   IPI00982315   IPI00978610   IPI00978965   IPI00982973   
Protein Interaction databases
DIP (DOE-UCLA)P01266
IntAct (EBI)P01266
FunCoupENSG00000042832
BioGRIDTG
IntegromeDBTG
STRING (EMBL)TG
Ontologies - Pathways
QuickGOP01266
Ontology : AmiGOreceptor activity  hormone activity  extracellular region  extracellular space  integral component of plasma membrane  thyroid hormone generation  signal transduction  synapse assembly  cell surface  iodide transport  thyroid gland development  regulation of myelination  neurexin family protein binding  hormone biosynthetic process  synapse  
Ontology : EGO-EBIreceptor activity  hormone activity  extracellular region  extracellular space  integral component of plasma membrane  thyroid hormone generation  signal transduction  synapse assembly  cell surface  iodide transport  thyroid gland development  regulation of myelination  neurexin family protein binding  hormone biosynthetic process  synapse  
Pathways : KEGGThyroid hormone synthesis    Autoimmune thyroid disease   
Protein Interaction DatabaseTG
DoCM (Curated mutations)TG
Wikipedia pathwaysTG
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerTG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TG
dbVarTG
ClinVarTG
1000_GenomesTG 
Exome Variant ServerTG
SNP (GeneSNP Utah)TG
SNP : HGBaseTG
Genetic variants : HAPMAPTG
Genomic Variants (DGV)TG [DGVbeta]
Mutations
ICGC Data PortalENSG00000042832 
Somatic Mutations in Cancer : COSMICTG 
CONAN: Copy Number AnalysisTG 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)8:133879205-134147143
Mutations and Diseases : HGMDTG
OMIM188450    274700    608175   
MedgenTG
NextProtP01266 [Medical]
GENETestsTG
Disease Genetic AssociationTG
Huge Navigator TG [HugePedia]  TG [HugeCancerGEM]
snp3D : Map Gene to Disease7038
DGIdb (Drug Gene Interaction db)TG
General knowledge
Homologs : HomoloGeneTG
Homology/Alignments : Family Browser (UCSC)TG
Phylogenetic Trees/Animal Genes : TreeFamTG
Chemical/Protein Interactions : CTD7038
Chemical/Pharm GKB GenePA36479
Clinical trialTG
Cancer Resource (Charite)ENSG00000042832
Other databases
Probes
Litterature
PubMed140 Pubmed reference(s) in Entrez
CoreMineTG
GoPubMedTG
iHOPTG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 19:00:34 CET 2015

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