Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TGIF1 (TGFB-induced factor homeobox 1)

Identity

Other namesHPE4
TGIF
HGNC (Hugo) TGIF1
LocusID (NCBI) 7050
Location 18p11.31
Location_base_pair Starts at 3450172 and ends at 3458406 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TGIF1   11776
Entrez_Gene (NCBI)TGIF1  7050  TGFB-induced factor homeobox 1
Cards
GeneCards (Weizmann)TGIF1
Ensembl (Hinxton)ENSG00000177426 [Gene_View]  chr18:3450172-3458406 [Contig_View]  TGIF1 [Vega]
AceView (NCBI)TGIF1
Genatlas (Paris)TGIF1
SOURCE (Stanford)NM_003244 NM_170695 NM_173207 NM_173208 NM_173209 NM_173210 NM_173211 NM_174886
Genomic and cartography
GoldenPath (UCSC)TGIF1  -  18p11.31   chr18:3450172-3458406 +  18p11.31   [Description]    (hg19-Feb_2009)
EnsemblTGIF1 - 18p11.31 [CytoView]
Mapping of homologs : NCBITGIF1 [Mapview]
OMIM142946   602630   605389   
Gene and transcription
Genbank (Entrez)AF179900 AI813434 AK026766 AK291112 AK309471
RefSeq transcript (SRS)NM_003244 NM_170695 NM_173207 NM_173208 NM_173209 NM_173210 NM_173211 NM_174886
RefSeq transcript (Entrez)NM_003244 NM_170695 NM_173207 NM_173208 NM_173209 NM_173210 NM_173211 NM_174886
RefSeq genomic (SRS)AC_000150 NC_000018 NC_018929 NG_007447 NT_010859 NW_001838461 NW_004078094
RefSeq genomic (Entrez)AC_000150 NC_000018 NC_018929 NG_007447 NT_010859 NW_001838461 NW_004078094
Consensus coding sequences : CCDS (NCBI)TGIF1
Cluster EST : UnigeneHs.373550 [ SRS ] Hs.373550 [ NCBI ]
CGAP (NCI)Hs.373550
Alternative Splicing : Fast-db (Paris)GSHG0013880
Alternative Splicing GalleryENSG00000177426
Gene ExpressionTGIF1 [ NCBI-GEO ]   TGIF1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15583 (SRS) Q15583 (Uniprot)
NextProtQ15583
With graphics : InterProQ15583
Splice isoforms : SwissVarQ15583(Swissvar)
Domaine pattern : Prosite (SRS)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (SRS)Homeobox_KN_domain    Homeodomain    Homeodomain-like   
Domains : Interpro (EBI)Homeobox_KN_domain    Homeodomain    Homeodomain-like   
Related proteins : CluSTrQ15583
Domain families : Pfam (SRS)Homeobox_KN (PF05920)   
Domain families : Pfam (Sanger)Homeobox_KN (PF05920)   
Domain families : Pfam (NCBI)pfam05920   
Domain families : Smart (EMBL)HOX (SM00389)  
DMDM7050
Blocks (Seattle)Q15583
PDB (SRS)2LK2   
PDB (PDBSum)2LK2   
PDB (IMB)2LK2   
PDB (RSDB)2LK2   
Human Protein AtlasENSG00000177426
HPRD04023
IPIIPI00297138   IPI00396515   IPI00334585   IPI01022090   IPI01021959   IPI01021590   IPI01021438   IPI01020967   IPI01020738   IPI01022990   IPI01022819   IPI01022663   IPI00334558   
Protein Interaction databases
DIP (DOE-UCLA)Q15583
IntAct (EBI)Q15583
FunCoupENSG00000177426
REACTOMETGIF1
Protein Interaction Database7050
BioGRIDTGIF1
InParanoidQ15583
Interologous Interaction database Q15583
IntegromeDBTGIF1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TGIF1
SNP (GeneSNP Utah)TGIF1
SNP : HGBaseTGIF1
Genetic variants : HAPMAPTGIF1
Somatic Mutations in Cancer : COSMICTGIF1 
CONAN: Copy Number AnalysisTGIF1 
Mutations and Diseases : HGMDTGIF1
OMIM142946    602630    605389   
GENETests142946    602630    605389   
Disease Genetic AssociationTGIF1
Huge Navigator TGIF1 [HugePedia]  TGIF1 [HugeCancerGEM]
Genomic VariantsTGIF1  TGIF1 [DGVbeta]
snp3D : Map Gene to Disease7050
General knowledge
Homologs : HomoloGeneTGIF1
Homology/Alignments : Family Browser (UCSC)TGIF1
Phylogenetic Trees/Animal Genes : TreeFamTGIF1
Chemical/Protein Interactions : CTD7050
Chemical/Pharm GKB GenePA36489
Clinical trialTGIF1
Cancer Resource (Charite)ENSG00000177426
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  neural tube closure  chromatin binding  sequence-specific DNA binding transcription factor activity  transcription corepressor activity  nucleoplasm  transcription, DNA-dependent  transcription initiation from RNA polymerase II promoter  transforming growth factor beta receptor signaling pathway  multicellular organismal development  determination of left/right symmetry  negative regulation of cell proliferation  dorsal/ventral pattern formation  gene expression  response to drug  sequence-specific DNA binding  positive regulation of neuron differentiation  positive regulation of fibroblast proliferation  negative regulation of retinoic acid receptor signaling pathway  retina development in camera-type eye  co-SMAD binding  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  neural tube closure  chromatin binding  sequence-specific DNA binding transcription factor activity  transcription corepressor activity  nucleoplasm  transcription, DNA-dependent  transcription initiation from RNA polymerase II promoter  transforming growth factor beta receptor signaling pathway  multicellular organismal development  determination of left/right symmetry  negative regulation of cell proliferation  dorsal/ventral pattern formation  gene expression  response to drug  sequence-specific DNA binding  positive regulation of neuron differentiation  positive regulation of fibroblast proliferation  negative regulation of retinoic acid receptor signaling pathway  retina development in camera-type eye  co-SMAD binding  
Other databases
Probes
Litterature
PubMed60 Pubmed reference(s) in Entrez
PubGeneTGIF1
iHOPTGIF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:30:27 CEST 2013
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