Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TGIF1 (TGFB-induced factor homeobox 1)

Identity

Other namesHPE4
TGIF
HGNC (Hugo) TGIF1
LocusID (NCBI) 7050
Location 18p11.31
Location_base_pair Starts at 3449411 and ends at 3458406 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TGIF1   11776
Cards
Entrez_Gene (NCBI)TGIF1  7050  TGFB-induced factor homeobox 1
GeneCards (Weizmann)TGIF1
Ensembl (Hinxton)ENSG00000177426 [Gene_View]  chr18:3449411-3458406 [Contig_View]  TGIF1 [Vega]
ICGC DataPortalENSG00000177426
cBioPortalTGIF1
AceView (NCBI)TGIF1
Genatlas (Paris)TGIF1
WikiGenes7050
SOURCE (Princeton)NM_001278682 NM_001278684 NM_001278686 NM_003244 NM_170695 NM_173207 NM_173208 NM_173209 NM_173210 NM_173211 NM_174886
Genomic and cartography
GoldenPath (UCSC)TGIF1  -  18p11.31   chr18:3449411-3458406 +  18p11.31   [Description]    (hg19-Feb_2009)
EnsemblTGIF1 - 18p11.31 [CytoView]
Mapping of homologs : NCBITGIF1 [Mapview]
OMIM142946   602630   
Gene and transcription
Genbank (Entrez)AF179900 AI813434 AK026766 AK291112 AK307230
RefSeq transcript (Entrez)NM_001278682 NM_001278684 NM_001278686 NM_003244 NM_170695 NM_173207 NM_173208 NM_173209 NM_173210 NM_173211 NM_174886
RefSeq genomic (Entrez)AC_000150 NC_000018 NC_018929 NG_007447 NT_010859 NW_001838461 NW_004929409
Consensus coding sequences : CCDS (NCBI)TGIF1
Cluster EST : UnigeneHs.373550 [ NCBI ]
CGAP (NCI)Hs.373550
Alternative Splicing : Fast-db (Paris)GSHG0013880
Alternative Splicing GalleryENSG00000177426
Gene ExpressionTGIF1 [ NCBI-GEO ]     TGIF1 [ SEEK ]   TGIF1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15583 (Uniprot)
NextProtQ15583  [Medical]
With graphics : InterProQ15583
Splice isoforms : SwissVarQ15583 (Swissvar)
Domaine pattern : Prosite (Expaxy)HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox_dom [organisation]   Homeobox_KN_domain [organisation]   Homeodomain-like [organisation]  
Related proteins : CluSTrQ15583
Domain families : Pfam (Sanger)Homeobox_KN (PF05920)   
Domain families : Pfam (NCBI)pfam05920   
Domain families : Smart (EMBL)HOX (SM00389)  
DMDM Disease mutations7050
Blocks (Seattle)Q15583
PDB (SRS)2LK2   
PDB (PDBSum)2LK2   
PDB (IMB)2LK2   
PDB (RSDB)2LK2   
Human Protein AtlasENSG00000177426 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ15583
HPRD04023
IPIIPI00297138   IPI00396515   IPI00334585   IPI01022090   IPI01021959   IPI01021590   IPI01021438   IPI01020967   IPI01020738   IPI01022990   IPI01022819   IPI01022663   IPI00334558   
Protein Interaction databases
DIP (DOE-UCLA)Q15583
IntAct (EBI)Q15583
FunCoupENSG00000177426
BioGRIDTGIF1
InParanoidQ15583
Interologous Interaction database Q15583
IntegromeDBTGIF1
STRING (EMBL)TGIF1
Ontologies - Pathways
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  negative regulation of transcription from RNA polymerase II promoter  negative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription  RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription  neural tube closure  chromatin binding  sequence-specific DNA binding transcription factor activity  transcription corepressor activity  protein binding  nucleoplasm  transcription, DNA-templated  transcription initiation from RNA polymerase II promoter  transforming growth factor beta receptor signaling pathway  multicellular organismal development  determination of left/right symmetry  negative regulation of cell proliferation  dorsal/ventral pattern formation  gene expression  regulation of gastrulation  nodal signaling pathway  response to drug  positive regulation of neuron differentiation  positive regulation of fibroblast proliferation  negative regulation of retinoic acid receptor signaling pathway  retina development in camera-type eye  co-SMAD binding  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  negative regulation of transcription from RNA polymerase II promoter  negative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription  RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription  neural tube closure  chromatin binding  sequence-specific DNA binding transcription factor activity  transcription corepressor activity  protein binding  nucleoplasm  transcription, DNA-templated  transcription initiation from RNA polymerase II promoter  transforming growth factor beta receptor signaling pathway  multicellular organismal development  determination of left/right symmetry  negative regulation of cell proliferation  dorsal/ventral pattern formation  gene expression  regulation of gastrulation  nodal signaling pathway  response to drug  positive regulation of neuron differentiation  positive regulation of fibroblast proliferation  negative regulation of retinoic acid receptor signaling pathway  retina development in camera-type eye  co-SMAD binding  
Protein Interaction DatabaseTGIF1
Wikipedia pathwaysTGIF1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TGIF1
snp3D : Map Gene to Disease7050
SNP (GeneSNP Utah)TGIF1
SNP : HGBaseTGIF1
Genetic variants : HAPMAPTGIF1
Exome VariantTGIF1
1000_GenomesTGIF1 
ICGC programENSG00000177426 
Somatic Mutations in Cancer : COSMICTGIF1 
CONAN: Copy Number AnalysisTGIF1 
Mutations and Diseases : HGMDTGIF1
Mutations and Diseases : intOGenTGIF1
Genomic VariantsTGIF1  TGIF1 [DGVbeta]
dbVarTGIF1
ClinVarTGIF1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM142946    602630   
MedgenTGIF1
GENETestsTGIF1
Disease Genetic AssociationTGIF1
Huge Navigator TGIF1 [HugePedia]  TGIF1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneTGIF1
Homology/Alignments : Family Browser (UCSC)TGIF1
Phylogenetic Trees/Animal Genes : TreeFamTGIF1
Chemical/Protein Interactions : CTD7050
Chemical/Pharm GKB GenePA36489
Clinical trialTGIF1
Cancer Resource (Charite)ENSG00000177426
Other databases
Probes
Litterature
PubMed71 Pubmed reference(s) in Entrez
CoreMineTGIF1
iHOPTGIF1
OncoSearchTGIF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 17:07:30 CEST 2014

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