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TGIF2 (TGFB induced factor homeobox 2)

Identity

Alias_namesTGFB-induced factor 2 (TALE family homeobox)
TGFB-induced factor homeobox 2
Other alias-
HGNC (Hugo) TGIF2
LocusID (NCBI) 60436
Atlas_Id 42544
Location 20q11.23  [Link to chromosome band 20q11]
Location_base_pair Starts at 36573473 and ends at 36593952 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FDPS (1q22) / TGIF2 (20q11.23)TGIF2 (20q11.23) / DLGAP4 (20q11.23)TGIF2 (20q11.23) / TGIF2 (20q11.23)
TGIF2 20q11.23 / DLGAP4 20q11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TGIF2   15764
Cards
Entrez_Gene (NCBI)TGIF2  60436  TGFB induced factor homeobox 2
Aliases
GeneCards (Weizmann)TGIF2
Ensembl hg19 (Hinxton)ENSG00000118707 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000118707 [Gene_View]  chr20:36573473-36593952 [Contig_View]  TGIF2 [Vega]
ICGC DataPortalENSG00000118707
TCGA cBioPortalTGIF2
AceView (NCBI)TGIF2
Genatlas (Paris)TGIF2
WikiGenes60436
SOURCE (Princeton)TGIF2
Genetics Home Reference (NIH)TGIF2
Genomic and cartography
GoldenPath hg38 (UCSC)TGIF2  -     chr20:36573473-36593952 +  20q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TGIF2  -     20q11.23   [Description]    (hg19-Feb_2009)
EnsemblTGIF2 - 20q11.23 [CytoView hg19]  TGIF2 - 20q11.23 [CytoView hg38]
Mapping of homologs : NCBITGIF2 [Mapview hg19]  TGIF2 [Mapview hg38]
OMIM607294   
Gene and transcription
Genbank (Entrez)AB042646 AF055012 AK074802 AK074829 AK313919
RefSeq transcript (Entrez)NM_001199513 NM_001199514 NM_001199515 NM_021809
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TGIF2
Cluster EST : UnigeneHs.632264 [ NCBI ]
CGAP (NCI)Hs.632264
Alternative Splicing GalleryENSG00000118707
Gene ExpressionTGIF2 [ NCBI-GEO ]   TGIF2 [ EBI - ARRAY_EXPRESS ]   TGIF2 [ SEEK ]   TGIF2 [ MEM ]
Gene Expression Viewer (FireBrowse)TGIF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)60436
GTEX Portal (Tissue expression)TGIF2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZN2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZN2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZN2
Splice isoforms : SwissVarQ9GZN2
PhosPhoSitePlusQ9GZN2
Domaine pattern : Prosite (Expaxy)HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_dom    Homeobox_KN_domain   
Domain families : Pfam (Sanger)Homeobox_KN (PF05920)   
Domain families : Pfam (NCBI)pfam05920   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)TGIF2
DMDM Disease mutations60436
Blocks (Seattle)TGIF2
SuperfamilyQ9GZN2
Human Protein AtlasENSG00000118707
Peptide AtlasQ9GZN2
HPRD06293
IPIIPI00029174   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZN2
IntAct (EBI)Q9GZN2
FunCoupENSG00000118707
BioGRIDTGIF2
STRING (EMBL)TGIF2
ZODIACTGIF2
Ontologies - Pathways
QuickGOQ9GZN2
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  negative regulation of transcription from RNA polymerase II promoter  DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  nucleoplasm  nucleoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  regulation of gastrulation  nodal signaling pathway  positive regulation of neuron differentiation  retina development in camera-type eye  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  negative regulation of transcription from RNA polymerase II promoter  DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  nucleoplasm  nucleoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  regulation of gastrulation  nodal signaling pathway  positive regulation of neuron differentiation  retina development in camera-type eye  
NDEx NetworkTGIF2
Atlas of Cancer Signalling NetworkTGIF2
Wikipedia pathwaysTGIF2
Orthology - Evolution
OrthoDB60436
GeneTree (enSembl)ENSG00000118707
Phylogenetic Trees/Animal Genes : TreeFamTGIF2
HOVERGENQ9GZN2
HOGENOMQ9GZN2
Homologs : HomoloGeneTGIF2
Homology/Alignments : Family Browser (UCSC)TGIF2
Gene fusions - Rearrangements
Fusion : MitelmanTGIF2/DLGAP4 [20q11.23/20q11.23]  
Fusion: TCGATGIF2 20q11.23 DLGAP4 20q11.23 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTGIF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TGIF2
dbVarTGIF2
ClinVarTGIF2
1000_GenomesTGIF2 
Exome Variant ServerTGIF2
ExAC (Exome Aggregation Consortium)TGIF2 (select the gene name)
Genetic variants : HAPMAP60436
Genomic Variants (DGV)TGIF2 [DGVbeta]
DECIPHERTGIF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTGIF2 
Mutations
ICGC Data PortalTGIF2 
TCGA Data PortalTGIF2 
Broad Tumor PortalTGIF2
OASIS PortalTGIF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTGIF2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTGIF2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TGIF2
DgiDB (Drug Gene Interaction Database)TGIF2
DoCM (Curated mutations)TGIF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TGIF2 (select a term)
intoGenTGIF2
Cancer3DTGIF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607294   
Orphanet
MedgenTGIF2
Genetic Testing Registry TGIF2
NextProtQ9GZN2 [Medical]
TSGene60436
GENETestsTGIF2
Target ValidationTGIF2
Huge Navigator TGIF2 [HugePedia]
snp3D : Map Gene to Disease60436
BioCentury BCIQTGIF2
ClinGenTGIF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD60436
Chemical/Pharm GKB GenePA38035
Clinical trialTGIF2
Miscellaneous
canSAR (ICR)TGIF2 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTGIF2
EVEXTGIF2
GoPubMedTGIF2
iHOPTGIF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:16:48 CEST 2017

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