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TGIF2 (TGFB induced factor homeobox 2)

Identity

Alias (NCBI)-
HGNC (Hugo) TGIF2
HGNC Previous nameTGFB-induced factor 2 (TALE family homeobox)
 TGFB-induced factor homeobox 2
LocusID (NCBI) 60436
Atlas_Id 42544
Location 20q11.23  [Link to chromosome band 20q11]
Location_base_pair Starts at 36573597 and ends at 36593949 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FDPS (1q22) / TGIF2 (20q11.23)TGIF2 (20q11.23) / DLGAP4 (20q11.23)TGIF2 (20q11.23) / TGIF2 (20q11.23)
TGIF2 20q11.23 / DLGAP4 20q11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TGIF2   15764
Cards
Entrez_Gene (NCBI)TGIF2    TGFB induced factor homeobox 2
Aliases
GeneCards (Weizmann)TGIF2
Ensembl hg19 (Hinxton)ENSG00000118707 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000118707 [Gene_View]  ENSG00000118707 [Sequence]  chr20:36573597-36593949 [Contig_View]  TGIF2 [Vega]
ICGC DataPortalENSG00000118707
TCGA cBioPortalTGIF2
AceView (NCBI)TGIF2
Genatlas (Paris)TGIF2
SOURCE (Princeton)TGIF2
Genetics Home Reference (NIH)TGIF2
Genomic and cartography
GoldenPath hg38 (UCSC)TGIF2  -     chr20:36573597-36593949 +  20q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TGIF2  -     20q11.23   [Description]    (hg19-Feb_2009)
GoldenPathTGIF2 - 20q11.23 [CytoView hg19]  TGIF2 - 20q11.23 [CytoView hg38]
ImmunoBaseENSG00000118707
Genome Data Viewer NCBITGIF2 [Mapview hg19]  
OMIM607294   
Gene and transcription
Genbank (Entrez)AB042646 AF055012 AK074802 AK074829 AK313919
RefSeq transcript (Entrez)NM_001199513 NM_001199514 NM_001199515 NM_021809
Consensus coding sequences : CCDS (NCBI)TGIF2
Gene ExpressionTGIF2 [ NCBI-GEO ]   TGIF2 [ EBI - ARRAY_EXPRESS ]   TGIF2 [ SEEK ]   TGIF2 [ MEM ]
Gene Expression Viewer (FireBrowse)TGIF2 [ Firebrowse - Broad ]
GenevisibleExpression of TGIF2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)60436
GTEX Portal (Tissue expression)TGIF2
Human Protein AtlasENSG00000118707-TGIF2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZN2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZN2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZN2
PhosPhoSitePlusQ9GZN2
Domaine pattern : Prosite (Expaxy)HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like_sf    Homeobox_dom    Homeobox_KN_domain   
Domain families : Pfam (Sanger)Homeobox_KN (PF05920)   
Domain families : Pfam (NCBI)pfam05920   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)TGIF2
SuperfamilyQ9GZN2
AlphaFold pdb e-kbQ9GZN2   
Human Protein Atlas [tissue]ENSG00000118707-TGIF2 [tissue]
HPRD06293
Protein Interaction databases
DIP (DOE-UCLA)Q9GZN2
IntAct (EBI)Q9GZN2
BioGRIDTGIF2
STRING (EMBL)TGIF2
ZODIACTGIF2
Ontologies - Pathways
QuickGOQ9GZN2
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  negative regulation of transcription by RNA polymerase II  chromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  nucleus  nucleoplasm  nucleoplasm  centrosome  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  regulation of gastrulation  nodal signaling pathway  positive regulation of neuron differentiation  retina development in camera-type eye  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  negative regulation of transcription by RNA polymerase II  chromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  nucleus  nucleoplasm  nucleoplasm  centrosome  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  regulation of gastrulation  nodal signaling pathway  positive regulation of neuron differentiation  retina development in camera-type eye  sequence-specific double-stranded DNA binding  
NDEx NetworkTGIF2
Atlas of Cancer Signalling NetworkTGIF2
Wikipedia pathwaysTGIF2
Orthology - Evolution
OrthoDB60436
GeneTree (enSembl)ENSG00000118707
Phylogenetic Trees/Animal Genes : TreeFamTGIF2
Homologs : HomoloGeneTGIF2
Homology/Alignments : Family Browser (UCSC)TGIF2
Gene fusions - Rearrangements
Fusion : MitelmanTGIF2/DLGAP4 [20q11.23/20q11.23]  
Fusion : QuiverTGIF2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTGIF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TGIF2
dbVarTGIF2
ClinVarTGIF2
MonarchTGIF2
1000_GenomesTGIF2 
Exome Variant ServerTGIF2
GNOMAD BrowserENSG00000118707
Varsome BrowserTGIF2
ACMGTGIF2 variants
VarityQ9GZN2
Genomic Variants (DGV)TGIF2 [DGVbeta]
DECIPHERTGIF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTGIF2 
Mutations
ICGC Data PortalTGIF2 
TCGA Data PortalTGIF2 
Broad Tumor PortalTGIF2
OASIS PortalTGIF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTGIF2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTGIF2
Mutations and Diseases : HGMDTGIF2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTGIF2
DgiDB (Drug Gene Interaction Database)TGIF2
DoCM (Curated mutations)TGIF2
CIViC (Clinical Interpretations of Variants in Cancer)TGIF2
Cancer3DTGIF2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607294   
Orphanet
DisGeNETTGIF2
MedgenTGIF2
Genetic Testing Registry TGIF2
NextProtQ9GZN2 [Medical]
GENETestsTGIF2
Target ValidationTGIF2
Huge Navigator TGIF2 [HugePedia]
ClinGenTGIF2
Clinical trials, drugs, therapy
MyCancerGenomeTGIF2
Protein Interactions : CTDTGIF2
Pharm GKB GenePA38035
PharosQ9GZN2
Clinical trialTGIF2
Miscellaneous
canSAR (ICR)TGIF2
HarmonizomeTGIF2
DataMed IndexTGIF2
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTGIF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:34:56 CEST 2021

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