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TGM1 (transglutaminase 1)

Identity

Other namesARCI1
ICR2
KTG
LI
LI1
TGASE
TGK
HGNC (Hugo) TGM1
LocusID (NCBI) 7051
Location 14q12
Location_base_pair Starts at 24718320 and ends at 24732416 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TGM1   11777
Cards
Entrez_Gene (NCBI)TGM1  7051  transglutaminase 1
GeneCards (Weizmann)TGM1
Ensembl (Hinxton)ENSG00000092295 [Gene_View]  chr14:24718320-24732416 [Contig_View]  TGM1 [Vega]
ICGC DataPortalENSG00000092295
AceView (NCBI)TGM1
Genatlas (Paris)TGM1
WikiGenes7051
SOURCE (Princeton)NM_000359
Genomic and cartography
GoldenPath (UCSC)TGM1  -  14q12   chr14:24718320-24732416 -  14q12   [Description]    (hg19-Feb_2009)
EnsemblTGM1 - 14q12 [CytoView]
Mapping of homologs : NCBITGM1 [Mapview]
OMIM190195   242300   
Gene and transcription
Genbank (Entrez)AK291350 AK299436 AK301652 AK315819 AK315828
RefSeq transcript (Entrez)NM_000359
RefSeq genomic (Entrez)AC_000146 NC_000014 NC_018925 NG_007150 NT_026437 NW_001838110 NW_004929393
Consensus coding sequences : CCDS (NCBI)TGM1
Cluster EST : UnigeneHs.508950 [ NCBI ]
CGAP (NCI)Hs.508950
Alternative Splicing : Fast-db (Paris)GSHG0009264
Alternative Splicing GalleryENSG00000092295
Gene ExpressionTGM1 [ NCBI-GEO ]     TGM1 [ SEEK ]   TGM1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP22735 (Uniprot)
NextProtP22735  [Medical]
With graphics : InterProP22735
Splice isoforms : SwissVarP22735 (Swissvar)
Catalytic activity : Enzyme2.3.2.13 [ Enzyme-Expasy ]   2.3.2.132.3.2.13 [ IntEnz-EBI ]   2.3.2.13 [ BRENDA ]   2.3.2.13 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)TRANSGLUTAMINASES (PS00547)   
Domains : Interpro (EBI)Gln_gamma-glutamylTfrase_euk    Ig-like_fold    Ig_E-set    Transglutaminase-like    Transglutaminase_C    Transglutaminase_CS    Transglutaminase_N   
Related proteins : CluSTrP22735
Domain families : Pfam (Sanger)Transglut_C (PF00927)    Transglut_core (PF01841)    Transglut_N (PF00868)   
Domain families : Pfam (NCBI)pfam00927    pfam01841    pfam00868   
Domain families : Smart (EMBL)TGc (SM00460)  
DMDM Disease mutations7051
Blocks (Seattle)P22735
PDB (SRS)2XZZ   
PDB (PDBSum)2XZZ   
PDB (IMB)2XZZ   
PDB (RSDB)2XZZ   
Human Protein AtlasENSG00000092295
Peptide AtlasP22735
HPRD01824
IPIIPI00305622   IPI01014432   
Protein Interaction databases
DIP (DOE-UCLA)P22735
IntAct (EBI)P22735
FunCoupENSG00000092295
BioGRIDTGM1
IntegromeDBTGM1
STRING (EMBL)TGM1
Ontologies - Pathways
QuickGOP22735
Ontology : AmiGOcornified envelope  protein-glutamine gamma-glutamyltransferase activity  protein binding  cell-cell adherens junction  cellular protein modification process  organ morphogenesis  peptide cross-linking  keratinocyte differentiation  intrinsic component of membrane  keratinization  cell envelope organization  metal ion binding  extracellular vesicular exosome  
Ontology : EGO-EBIcornified envelope  protein-glutamine gamma-glutamyltransferase activity  protein binding  cell-cell adherens junction  cellular protein modification process  organ morphogenesis  peptide cross-linking  keratinocyte differentiation  intrinsic component of membrane  keratinization  cell envelope organization  metal ion binding  extracellular vesicular exosome  
Protein Interaction DatabaseTGM1
Wikipedia pathwaysTGM1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TGM1
SNP (GeneSNP Utah)TGM1
SNP : HGBaseTGM1
Genetic variants : HAPMAPTGM1
1000_GenomesTGM1 
ICGC programENSG00000092295 
CONAN: Copy Number AnalysisTGM1 
Somatic Mutations in Cancer : COSMICTGM1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)ABCC's LOVD - Leiden Open Variation Database
DECIPHER (Syndromes)14:24718320-24732416
Mutations and Diseases : HGMDTGM1
OMIM190195    242300   
MedgenTGM1
GENETestsTGM1
Disease Genetic AssociationTGM1
Huge Navigator TGM1 [HugePedia]  TGM1 [HugeCancerGEM]
Genomic VariantsTGM1  TGM1 [DGVbeta]
Exome VariantTGM1
dbVarTGM1
ClinVarTGM1
snp3D : Map Gene to Disease7051
General knowledge
Homologs : HomoloGeneTGM1
Homology/Alignments : Family Browser (UCSC)TGM1
Phylogenetic Trees/Animal Genes : TreeFamTGM1
Chemical/Protein Interactions : CTD7051
Chemical/Pharm GKB GenePA36490
Clinical trialTGM1
Cancer Resource (Charite)ENSG00000092295
Other databases
Probes
Litterature
PubMed104 Pubmed reference(s) in Entrez
CoreMineTGM1
GoPubMedTGM1
iHOPTGM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 18:01:21 CET 2014

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