TGM1 (transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase))

Identity

Other names	ICR2
	KTG
	LI
	LI1
	TGASE
	TGK
HGNC	TGM1
Location	14q11.2
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TGM1   11777
Entrez_Gene	TGM1  7051  transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)
	Cards
GeneCards	TGM1
Ensembl	TGM1 [Search_View]   ENSG00000092295 [Gene_View]
Genatlas	TGM1
GeneLynx	TGM1
eGenome	TGM1
euGene	7051
	Genomic and cartography
GoldenPath	TGM1  -  14q11.2   chr14:23788160-23802256 -  14q12   [Description]    (hg18-March_2006)
Ensembl	TGM1 - 14q12 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TGM1
	Gene and transcription
Genbank	AK291350 [ ENTREZ ]
Genbank	AK299436 [ ENTREZ ]
Genbank	AK315819 [ ENTREZ ]
Genbank	AK315828 [ ENTREZ ]
Genbank	AK315843 [ ENTREZ ]
RefSeq	NM_000359 [ SRS ]    NM_000359 [ ENTREZ ]
RefSeq	AC_000057 [ SRS ]    AC_000057 [ ENTREZ ]
RefSeq	AC_000146 [ SRS ]    AC_000146 [ ENTREZ ]
RefSeq	NC_000014 [ SRS ]    NC_000014 [ ENTREZ ]
RefSeq	NG_007150 [ SRS ]    NG_007150 [ ENTREZ ]
RefSeq	NT_026437 [ SRS ]    NT_026437 [ ENTREZ ]
RefSeq	NW_001838110 [ SRS ]    NW_001838110 [ ENTREZ ]
RefSeq	NW_925539 [ SRS ]    NW_925539 [ ENTREZ ]
AceView	TGM1 AceView - NCBI
Unigene	Hs.508950 [ SRS ]    Hs.508950 [ NCBI ]     HS508950 [ spliceNest ]
Fast-db	106 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P22735 [ SRS]    P22735 [ EXPASY ]     P22735 [ INTERPRO ]     P22735 [ UNIPROT ]
Prosite	PS00547 TRANSGLUTAMINASES [ SRS ]    PS00547 TRANSGLUTAMINASES [ Expasy ]
Interpro	IPR008957 Fibronectin_typ-III-like_fold [ SRS ]    IPR008957 Fibronectin_typ-III-like_fold [ EBI ]
Interpro	IPR013783 Ig-like_fold [ SRS ]    IPR013783 Ig-like_fold [ EBI ]
Interpro	IPR008958 Transglutaminase_C [ SRS ]    IPR008958 Transglutaminase_C [ EBI ]
Interpro	IPR013808 Transglutaminase_CS [ SRS ]    IPR013808 Transglutaminase_CS [ EBI ]
Interpro	IPR001102 Transglutaminase_N [ SRS ]    IPR001102 Transglutaminase_N [ EBI ]
Interpro	IPR002931 Trnsglumase_like [ SRS ]    IPR002931 Trnsglumase_like [ EBI ]
CluSTr	P22735
Pfam	PF00927 Transglut_C [ SRS ]    PF00927 Transglut_C [ Sanger ]    pfam00927 [ NCBI-CDD ]
Pfam	PF01841 Transglut_core [ SRS ]    PF01841 Transglut_core [ Sanger ]    pfam01841 [ NCBI-CDD ]
Pfam	PF00868 Transglut_N [ SRS ]    PF00868 Transglut_N [ Sanger ]    pfam00868 [ NCBI-CDD ]
Smart	SM00460 TGc [EMBL]
Blocks	P22735
HPRD	01824
	Protein Interaction databases
DIP	P22735
IntAct	P22735
	Polymorphism : SNP, mutations, diseases
OMIM	190195;242100;242300    [ map ]
GENECLINICS	190195;242100;242300
SNP	TGM1 [dbSNP-NCBI]
SNP	NM_000359 [SNP-NCI]
SNP	TGM1 [GeneSNPs - Utah]  TGM1] [HGBASE - SRS]
HAPMAP	TGM1 [HAPMAP]
HGMD	TGM1
	General knowledge
Family Browser	TGM1 [UCSC Family Browser]
SOURCE	NM_000359
SMD	Hs.508950
SAGE	Hs.508950
Enzyme	2.3.2.13 [ Enzyme-Expasy ]   2.3.2.13 [ Enzyme-SRS ]   2.3.2.13 [ IntEnz-EBI ]   2.3.2.13 [ BRENDA ]   2.3.2.13 [ KEGG ]   2.3.2.13 [ WIT ]
GO	cornified envelope [Amigo]  cornified envelope
GO	protein-glutamine gamma-glutamyltransferase activity [Amigo]  protein-glutamine gamma-glutamyltransferase activity
GO	calcium ion binding [Amigo]  calcium ion binding
GO	protein binding [Amigo]  protein binding
GO	cell-cell adherens junction [Amigo]  cell-cell adherens junction
GO	protein modification process [Amigo]  protein modification process
GO	acyltransferase activity [Amigo]  acyltransferase activity
GO	organ morphogenesis [Amigo]  organ morphogenesis
GO	membrane [Amigo]  membrane
GO	transferase activity [Amigo]  transferase activity
GO	peptide cross-linking [Amigo]  peptide cross-linking
GO	keratinocyte differentiation [Amigo]  keratinocyte differentiation
GO	intrinsic to membrane [Amigo]  intrinsic to membrane
GO	keratinization [Amigo]  keratinization
GO	cell envelope organization and biogenesis [Amigo]  cell envelope organization and biogenesis
PubGene	TGM1
TreeFam	TGM1
CTD	7051 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TGM1 Related clones (RZPD - Berlin)
	PubMed
PubMed	59 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:34:53 2008