TGM3 (transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase))

Identity

Other names	MGC126249
	MGC126250
	TGE
HGNC	TGM3
Location	20q11.2
Location_base_pair	Starts at 2224613 and ends at 2269725 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TGM3   11779
Entrez_Gene	TGM3  7053  transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
	Cards
GeneCards	TGM3
Ensembl	ENSG00000125780 [Gene_View]  TGM3 [Vega]
Genatlas	TGM3
	Genomic and cartography
GoldenPath	TGM3  -  20q11.2   chr20:2224613-2269725 +  20p13   [Description]    (hg18-March_2006)
Ensembl	TGM3 - 20p13 [CytoView]
NCBI	Mapview
OMIM	600238 Disease map [OMIM]
HomoloGene	TGM3
	Gene and transcription
Genbank	AI216028 [ ENTREZ ]
Genbank	AK290324 [ ENTREZ ]
Genbank	AK291351 [ ENTREZ ]
Genbank	AK308249 [ ENTREZ ]
Genbank	AK315236 [ ENTREZ ]
RefSeq	NM_003245 [ SRS ]    NM_003245 [ ENTREZ ]
RefSeq	AC_000063 [ SRS ]    AC_000063 [ ENTREZ ]
RefSeq	AC_000152 [ SRS ]    AC_000152 [ ENTREZ ]
RefSeq	NC_000020 [ SRS ]    NC_000020 [ ENTREZ ]
RefSeq	NT_011387 [ SRS ]    NT_011387 [ ENTREZ ]
RefSeq	NW_001838652 [ SRS ]    NW_001838652 [ ENTREZ ]
RefSeq	NW_927317 [ SRS ]    NW_927317 [ ENTREZ ]
CCDS	TGM3 CCDS - NCBI
AceView	TGM3 AceView - NCBI
Unigene	Hs.2022 [ SRS ]    Hs.2022 [ NCBI ]
Fast-db	1358 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q08188 [ SRS]    Q08188 [ EXPASY ]     Q08188 [ INTERPRO ]     Q08188 [ UNIPROT ] Q08188 [ VarSplice FASTA ]
Prosite	PS00547 TRANSGLUTAMINASES [ SRS ]    PS00547 TRANSGLUTAMINASES [ Expasy ]
Interpro	IPR013783 Ig-like_fold [ SRS ]    IPR013783 Ig-like_fold [ EBI ]
Interpro	IPR008958 Transglutaminase_C [ SRS ]    IPR008958 Transglutaminase_C [ EBI ]
Interpro	IPR013808 Transglutaminase_CS [ SRS ]    IPR013808 Transglutaminase_CS [ EBI ]
Interpro	IPR001102 Transglutaminase_N [ SRS ]    IPR001102 Transglutaminase_N [ EBI ]
Interpro	IPR002931 Trnsglumase_like [ SRS ]    IPR002931 Trnsglumase_like [ EBI ]
CluSTr	Q08188
Pfam	PF00927 Transglut_C [ SRS ]    PF00927 Transglut_C [ Sanger ]    pfam00927 [ NCBI-CDD ]
Pfam	PF01841 Transglut_core [ SRS ]    PF01841 Transglut_core [ Sanger ]    pfam01841 [ NCBI-CDD ]
Pfam	PF00868 Transglut_N [ SRS ]    PF00868 Transglut_N [ Sanger ]    pfam00868 [ NCBI-CDD ]
Smart	SM00460 TGc [EMBL]
Blocks	Q08188
PDB	1L9M [ SRS ]    1L9M [ PdbSum ],   1L9M [ IMB ]   1L9M [ RSDB ]
PDB	1L9N [ SRS ]    1L9N [ PdbSum ],   1L9N [ IMB ]   1L9N [ RSDB ]
PDB	1NUD [ SRS ]    1NUD [ PdbSum ],   1NUD [ IMB ]   1NUD [ RSDB ]
PDB	1NUF [ SRS ]    1NUF [ PdbSum ],   1NUF [ IMB ]   1NUF [ RSDB ]
PDB	1NUG [ SRS ]    1NUG [ PdbSum ],   1NUG [ IMB ]   1NUG [ RSDB ]
PDB	1RLE [ SRS ]    1RLE [ PdbSum ],   1RLE [ IMB ]   1RLE [ RSDB ]
PDB	1SGX [ SRS ]    1SGX [ PdbSum ],   1SGX [ IMB ]   1SGX [ RSDB ]
PDB	1VJJ [ SRS ]    1VJJ [ PdbSum ],   1VJJ [ IMB ]   1VJJ [ RSDB ]
HPRD	02584
	Protein Interaction databases
DIP	Q08188
IntAct	Q08188
	Polymorphism : SNP, mutations, diseases
OMIM	600238    [ map ]
GENETests	600238
SNP	TGM3 [dbSNP-NCBI]
SNP	NM_003245 [SNP-NCI]
SNP	TGM3 [GeneSNPs - Utah]  TGM3] [HGBASE - SRS]
HAPMAP	TGM3 [HAPMAP]
HGMD	TGM3
Genetic Association	TGM3
CDC HuGE	TGM3
	General knowledge
Family Browser	TGM3 [UCSC Family Browser]
SOURCE	NM_003245
SMD	Hs.2022
SAGE	Hs.2022
Enzyme	2.3.2.13 [ Enzyme-Expasy ]   2.3.2.13 [ Enzyme-SRS ]   2.3.2.13 [ IntEnz-EBI ]   2.3.2.13 [ BRENDA ]   2.3.2.13 [ KEGG ]
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	protein-glutamine gamma-glutamyltransferase activity [Amigo]  protein-glutamine gamma-glutamyltransferase activity
GO	GTPase activity [Amigo]  GTPase activity
GO	calcium ion binding [Amigo]  calcium ion binding
GO	GTP binding [Amigo]  GTP binding
GO	cytoplasm [Amigo]  cytoplasm
GO	protein modification process [Amigo]  protein modification process
GO	acyltransferase activity [Amigo]  acyltransferase activity
GO	transferase activity, transferring acyl groups [Amigo]  transferase activity, transferring acyl groups
GO	peptide cross-linking [Amigo]  peptide cross-linking
GO	GDP binding [Amigo]  GDP binding
GO	keratinocyte differentiation [Amigo]  keratinocyte differentiation
GO	keratinocyte differentiation [Amigo]  keratinocyte differentiation
GO	hair follicle morphogenesis [Amigo]  hair follicle morphogenesis
GO	extrinsic to internal side of plasma membrane [Amigo]  extrinsic to internal side of plasma membrane
GO	keratinization [Amigo]  keratinization
GO	cell envelope organization and biogenesis [Amigo]  cell envelope organization and biogenesis
GO	protein tetramerization [Amigo]  protein tetramerization
PubGene	TGM3
TreeFam	TGM3
CTD	7053 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TGM3 Related clones (RZPD - Berlin)
	PubMed
PubMed	32 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:15:27 2008