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TGM4 (transglutaminase 4)

Identity

Other namesTGP
hTGP
HGNC (Hugo) TGM4
LocusID (NCBI) 7047
Location 3p21.31
Location_base_pair Starts at 44916098 and ends at 44956088 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TGM4   11780
Cards
Entrez_Gene (NCBI)TGM4  7047  transglutaminase 4
GeneCards (Weizmann)TGM4
Ensembl hg19 (Hinxton)ENSG00000163810 [Gene_View]  chr3:44916098-44956088 [Contig_View]  TGM4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000163810 [Gene_View]  chr3:44916098-44956088 [Contig_View]  TGM4 [Vega]
ICGC DataPortalENSG00000163810
cBioPortalTGM4
AceView (NCBI)TGM4
Genatlas (Paris)TGM4
WikiGenes7047
SOURCE (Princeton)TGM4
Genomic and cartography
GoldenPath hg19 (UCSC)TGM4  -     chr3:44916098-44956088 +  3p21.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TGM4  -     3p21.31   [Description]    (hg38-Dec_2013)
EnsemblTGM4 - 3p21.31 [CytoView hg19]  TGM4 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBITGM4 [Mapview hg19]  TGM4 [Mapview hg38]
OMIM600585   
Gene and transcription
Genbank (Entrez)AK125536 AK130286 AK300523 AK312936 BC007003
RefSeq transcript (Entrez)NM_003241
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NT_022517 NW_001838877 NW_004929309
Consensus coding sequences : CCDS (NCBI)TGM4
Cluster EST : UnigeneHs.438265 [ NCBI ]
CGAP (NCI)Hs.438265
Alternative Splicing : Fast-db (Paris)GSHG0020757
Alternative Splicing GalleryENSG00000163810
Gene ExpressionTGM4 [ NCBI-GEO ]     TGM4 [ SEEK ]   TGM4 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49221 (Uniprot)
NextProtP49221  [Medical]
With graphics : InterProP49221
Splice isoforms : SwissVarP49221 (Swissvar)
Catalytic activity : Enzyme2.3.2.13 [ Enzyme-Expasy ]   2.3.2.132.3.2.13 [ IntEnz-EBI ]   2.3.2.13 [ BRENDA ]   2.3.2.13 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)TRANSGLUTAMINASES (PS00547)   
Domains : Interpro (EBI)Gln_gamma-glutamylTfrase_euk    Ig-like_fold    Ig_E-set    Transglutaminase-like    Transglutaminase_C    Transglutaminase_CS    Transglutaminase_N   
Related proteins : CluSTrP49221
Domain families : Pfam (Sanger)Transglut_C (PF00927)    Transglut_core (PF01841)    Transglut_N (PF00868)   
Domain families : Pfam (NCBI)pfam00927    pfam01841    pfam00868   
Domain families : Smart (EMBL)TGc (SM00460)  
DMDM Disease mutations7047
Blocks (Seattle)P49221
Human Protein AtlasENSG00000163810
Peptide AtlasP49221
HPRD08997
IPIIPI00290396   IPI00442749   IPI00925354   
Protein Interaction databases
DIP (DOE-UCLA)P49221
IntAct (EBI)P49221
FunCoupENSG00000163810
BioGRIDTGM4
IntegromeDBTGM4
STRING (EMBL)TGM4
Ontologies - Pathways
QuickGOP49221
Ontology : AmiGOprotein-glutamine gamma-glutamyltransferase activity  cytoplasm  Golgi apparatus  peptide cross-linking  extracellular matrix  mating plug formation  metal ion binding  extracellular vesicular exosome  
Ontology : EGO-EBIprotein-glutamine gamma-glutamyltransferase activity  cytoplasm  Golgi apparatus  peptide cross-linking  extracellular matrix  mating plug formation  metal ion binding  extracellular vesicular exosome  
Protein Interaction DatabaseTGM4
DoCM (Curated mutations)TGM4
Wikipedia pathwaysTGM4
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerTGM4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TGM4
dbVarTGM4
ClinVarTGM4
1000_GenomesTGM4 
Exome Variant ServerTGM4
SNP (GeneSNP Utah)TGM4
SNP : HGBaseTGM4
Genetic variants : HAPMAPTGM4
Genomic VariantsTGM4  TGM4 [DGVbeta]
Mutations
ICGC Data PortalENSG00000163810 
Somatic Mutations in Cancer : COSMICTGM4 
CONAN: Copy Number AnalysisTGM4 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)3:44916098-44956088
Mutations and Diseases : HGMDTGM4
OMIM600585   
MedgenTGM4
NextProtP49221 [Medical]
GENETestsTGM4
Disease Genetic AssociationTGM4
Huge Navigator TGM4 [HugePedia]  TGM4 [HugeCancerGEM]
snp3D : Map Gene to Disease7047
DGIdb (Drug Gene Interaction db)TGM4
General knowledge
Homologs : HomoloGeneTGM4
Homology/Alignments : Family Browser (UCSC)TGM4
Phylogenetic Trees/Animal Genes : TreeFamTGM4
Chemical/Protein Interactions : CTD7047
Chemical/Pharm GKB GenePA36493
Clinical trialTGM4
Cancer Resource (Charite)ENSG00000163810
Other databases
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
CoreMineTGM4
GoPubMedTGM4
iHOPTGM4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 01:54:08 CET 2014

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