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TGM4 (transglutaminase 4)

Identity

Alias (NCBI)TGP
hTGP
HGNC (Hugo) TGM4
HGNC Alias symbTGP
HGNC Previous nametransglutaminase 4 (prostate)
LocusID (NCBI) 7047
Atlas_Id 42545
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 44874608 and ends at 44914989 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TGM4   11780
Cards
Entrez_Gene (NCBI)TGM4    transglutaminase 4
AliasesTGP; hTGP
GeneCards (Weizmann)TGM4
Ensembl hg19 (Hinxton)ENSG00000163810 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163810 [Gene_View]  ENSG00000163810 [Sequence]  chr3:44874608-44914989 [Contig_View]  TGM4 [Vega]
ICGC DataPortalENSG00000163810
TCGA cBioPortalTGM4
AceView (NCBI)TGM4
Genatlas (Paris)TGM4
SOURCE (Princeton)TGM4
Genetics Home Reference (NIH)TGM4
Genomic and cartography
GoldenPath hg38 (UCSC)TGM4  -     chr3:44874608-44914989 +  3p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TGM4  -     3p21.31   [Description]    (hg19-Feb_2009)
GoldenPathTGM4 - 3p21.31 [CytoView hg19]  TGM4 - 3p21.31 [CytoView hg38]
ImmunoBaseENSG00000163810
Genome Data Viewer NCBITGM4 [Mapview hg19]  
OMIM600585   
Gene and transcription
Genbank (Entrez)AK092657 AK125536 AK130286 AK300523 AK312936
RefSeq transcript (Entrez)NM_003241
Consensus coding sequences : CCDS (NCBI)TGM4
Gene ExpressionTGM4 [ NCBI-GEO ]   TGM4 [ EBI - ARRAY_EXPRESS ]   TGM4 [ SEEK ]   TGM4 [ MEM ]
Gene Expression Viewer (FireBrowse)TGM4 [ Firebrowse - Broad ]
GenevisibleExpression of TGM4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7047
GTEX Portal (Tissue expression)TGM4
Human Protein AtlasENSG00000163810-TGM4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49221   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49221  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49221
Catalytic activity : Enzyme2.3.2.13 [ Enzyme-Expasy ]   2.3.2.132.3.2.13 [ IntEnz-EBI ]   2.3.2.13 [ BRENDA ]   2.3.2.13 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusP49221
Domaine pattern : Prosite (Expaxy)TRANSGLUTAMINASES (PS00547)   
Domains : Interpro (EBI)Ig-like_fold    Ig_E-set    Papain-like_cys_pep_sf    Transglutaminase-like    Transglutaminase-like_sf    Transglutaminase_animal    Transglutaminase_AS    Transglutaminase_C    Transglutaminase_C_sf    Transglutaminase_N   
Domain families : Pfam (Sanger)Transglut_C (PF00927)    Transglut_core (PF01841)    Transglut_N (PF00868)   
Domain families : Pfam (NCBI)pfam00927    pfam01841    pfam00868   
Domain families : Smart (EMBL)TGc (SM00460)  
Conserved Domain (NCBI)TGM4
SuperfamilyP49221
AlphaFold pdb e-kbP49221   
Human Protein Atlas [tissue]ENSG00000163810-TGM4 [tissue]
HPRD08997
Protein Interaction databases
DIP (DOE-UCLA)P49221
IntAct (EBI)P49221
BioGRIDTGM4
STRING (EMBL)TGM4
ZODIACTGM4
Ontologies - Pathways
QuickGOP49221
Ontology : AmiGOprotein-glutamine gamma-glutamyltransferase activity  protein-glutamine gamma-glutamyltransferase activity  cytoplasm  Golgi apparatus  peptide cross-linking  metal ion binding  collagen-containing extracellular matrix  collagen-containing extracellular matrix  extracellular exosome  
Ontology : EGO-EBIprotein-glutamine gamma-glutamyltransferase activity  protein-glutamine gamma-glutamyltransferase activity  cytoplasm  Golgi apparatus  peptide cross-linking  metal ion binding  collagen-containing extracellular matrix  collagen-containing extracellular matrix  extracellular exosome  
NDEx NetworkTGM4
Atlas of Cancer Signalling NetworkTGM4
Wikipedia pathwaysTGM4
Orthology - Evolution
OrthoDB7047
GeneTree (enSembl)ENSG00000163810
Phylogenetic Trees/Animal Genes : TreeFamTGM4
Homologs : HomoloGeneTGM4
Homology/Alignments : Family Browser (UCSC)TGM4
Gene fusions - Rearrangements
Fusion : QuiverTGM4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTGM4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TGM4
dbVarTGM4
ClinVarTGM4
MonarchTGM4
1000_GenomesTGM4 
Exome Variant ServerTGM4
GNOMAD BrowserENSG00000163810
Varsome BrowserTGM4
ACMGTGM4 variants
VarityP49221
Genomic Variants (DGV)TGM4 [DGVbeta]
DECIPHERTGM4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTGM4 
Mutations
ICGC Data PortalTGM4 
TCGA Data PortalTGM4 
Broad Tumor PortalTGM4
OASIS PortalTGM4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTGM4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTGM4
Mutations and Diseases : HGMDTGM4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTGM4
DgiDB (Drug Gene Interaction Database)TGM4
DoCM (Curated mutations)TGM4
CIViC (Clinical Interpretations of Variants in Cancer)TGM4
Cancer3DTGM4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600585   
Orphanet
DisGeNETTGM4
MedgenTGM4
Genetic Testing Registry TGM4
NextProtP49221 [Medical]
GENETestsTGM4
Target ValidationTGM4
Huge Navigator TGM4 [HugePedia]
ClinGenTGM4
Clinical trials, drugs, therapy
MyCancerGenomeTGM4
Protein Interactions : CTDTGM4
Pharm GKB GenePA36493
PharosP49221
Clinical trialTGM4
Miscellaneous
canSAR (ICR)TGM4
HarmonizomeTGM4
DataMed IndexTGM4
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTGM4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:34:57 CEST 2021

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