Atlas of Genetics and Cytogenetics in Oncology and Haematology

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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

Donate (in Euros)

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TGM4 (transglutaminase 4)


Other namesTGP
HGNC (Hugo) TGM4
LocusID (NCBI) 7047
Location 3p21.31
Location_base_pair Starts at 44916098 and ends at 44956088 bp from pter ( according to hg19-Feb_2009)

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



External links

HGNC (Hugo)TGM4   11780
Entrez_Gene (NCBI)TGM4  7047  transglutaminase 4
GeneCards (Weizmann)TGM4
Ensembl hg19 (Hinxton)ENSG00000163810 [Gene_View]  chr3:44916098-44956088 [Contig_View]  TGM4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000163810 [Gene_View]  chr3:44916098-44956088 [Contig_View]  TGM4 [Vega]
ICGC DataPortalENSG00000163810
AceView (NCBI)TGM4
Genatlas (Paris)TGM4
SOURCE (Princeton)TGM4
Genomic and cartography
GoldenPath hg19 (UCSC)TGM4  -     chr3:44916098-44956088 +  3p21.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TGM4  -     3p21.31   [Description]    (hg38-Dec_2013)
EnsemblTGM4 - 3p21.31 [CytoView hg19]  TGM4 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBITGM4 [Mapview hg19]  TGM4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK125536 AK130286 AK300523 AK312936 BC007003
RefSeq transcript (Entrez)NM_003241
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_022517 NW_004929309 NW_009646197
Consensus coding sequences : CCDS (NCBI)TGM4
Cluster EST : UnigeneHs.438265 [ NCBI ]
CGAP (NCI)Hs.438265
Alternative Splicing : Fast-db (Paris)GSHG0020757
Alternative Splicing GalleryENSG00000163810
Gene ExpressionTGM4 [ NCBI-GEO ]     TGM4 [ SEEK ]   TGM4 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49221 (Uniprot)
NextProtP49221  [Medical]
With graphics : InterProP49221
Splice isoforms : SwissVarP49221 (Swissvar)
Catalytic activity : Enzyme2.3.2.13 [ Enzyme-Expasy ] [ IntEnz-EBI ] [ BRENDA ] [ KEGG ]   
Domaine pattern : Prosite (Expaxy)TRANSGLUTAMINASES (PS00547)   
Domains : Interpro (EBI)Gln_gamma-glutamylTfrase_euk    Ig-like_fold    Ig_E-set    Transglutaminase-like    Transglutaminase_C    Transglutaminase_CS    Transglutaminase_N   
Related proteins : CluSTrP49221
Domain families : Pfam (Sanger)Transglut_C (PF00927)    Transglut_core (PF01841)    Transglut_N (PF00868)   
Domain families : Pfam (NCBI)pfam00927    pfam01841    pfam00868   
Domain families : Smart (EMBL)TGc (SM00460)  
DMDM Disease mutations7047
Blocks (Seattle)P49221
Human Protein AtlasENSG00000163810
Peptide AtlasP49221
IPIIPI00290396   IPI00442749   IPI00925354   
Protein Interaction databases
IntAct (EBI)P49221
Ontologies - Pathways
Ontology : AmiGOprotein-glutamine gamma-glutamyltransferase activity  cytoplasm  Golgi apparatus  peptide cross-linking  extracellular matrix  mating plug formation  metal ion binding  extracellular exosome  
Ontology : EGO-EBIprotein-glutamine gamma-glutamyltransferase activity  cytoplasm  Golgi apparatus  peptide cross-linking  extracellular matrix  mating plug formation  metal ion binding  extracellular exosome  
Protein Interaction DatabaseTGM4
DoCM (Curated mutations)TGM4
Wikipedia pathwaysTGM4
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerTGM4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TGM4
Exome Variant ServerTGM4
SNP (GeneSNP Utah)TGM4
Genetic variants : HAPMAPTGM4
Genomic Variants (DGV)TGM4 [DGVbeta]
ICGC Data PortalENSG00000163810 
Somatic Mutations in Cancer : COSMICTGM4 
CONAN: Copy Number AnalysisTGM4 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
DECIPHER (Syndromes)3:44916098-44956088
Mutations and Diseases : HGMDTGM4
NextProtP49221 [Medical]
Disease Genetic AssociationTGM4
Huge Navigator TGM4 [HugePedia]  TGM4 [HugeCancerGEM]
snp3D : Map Gene to Disease7047
DGIdb (Drug Gene Interaction db)TGM4
General knowledge
Homologs : HomoloGeneTGM4
Homology/Alignments : Family Browser (UCSC)TGM4
Phylogenetic Trees/Animal Genes : TreeFamTGM4
Chemical/Protein Interactions : CTD7047
Chemical/Pharm GKB GenePA36493
Clinical trialTGM4
Cancer Resource (Charite)ENSG00000163810
Other databases
PubMed22 Pubmed reference(s) in Entrez
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI


Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 17:37:11 CET 2015

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