Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TGM5 (transglutaminase 5)

Identity

Alias_symbol (synonym)TGX
Other aliasPSS2
TGASE5
TGASEX
TGM6
TGMX
HGNC (Hugo) TGM5
LocusID (NCBI) 9333
Atlas_Id 55043
Location 15q15.2  [Link to chromosome band 15q15]
Location_base_pair Starts at 43524793 and ends at 43559055 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CASC4 (15q15.3) / TGM5 (15q15.2)UBR1 (15q15.2) / TGM5 (15q15.2)CASC4 15q15.3 / TGM5 15q15.2
UBR1 15q15.2 / TGM5 15q15.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TGM5   11781
Cards
Entrez_Gene (NCBI)TGM5  9333  transglutaminase 5
AliasesPSS2; TGASE5; TGASEX; TGM6; 
TGMX; TGX
GeneCards (Weizmann)TGM5
Ensembl hg19 (Hinxton)ENSG00000104055 [Gene_View]  chr15:43524793-43559055 [Contig_View]  TGM5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000104055 [Gene_View]  chr15:43524793-43559055 [Contig_View]  TGM5 [Vega]
ICGC DataPortalENSG00000104055
TCGA cBioPortalTGM5
AceView (NCBI)TGM5
Genatlas (Paris)TGM5
WikiGenes9333
SOURCE (Princeton)TGM5
Genetics Home Reference (NIH)TGM5
Genomic and cartography
GoldenPath hg19 (UCSC)TGM5  -     chr15:43524793-43559055 -  15q15.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TGM5  -     15q15.2   [Description]    (hg38-Dec_2013)
EnsemblTGM5 - 15q15.2 [CytoView hg19]  TGM5 - 15q15.2 [CytoView hg38]
Mapping of homologs : NCBITGM5 [Mapview hg19]  TGM5 [Mapview hg38]
OMIM603805   609796   
Gene and transcription
Genbank (Entrez)AF035960 AF035961 AK298479 AW467571 BC039086
RefSeq transcript (Entrez)NM_004245 NM_201631
RefSeq genomic (Entrez)NC_000015 NC_018926 NG_016124 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)TGM5
Cluster EST : UnigeneHs.129719 [ NCBI ]
CGAP (NCI)Hs.129719
Alternative Splicing GalleryENSG00000104055
Gene ExpressionTGM5 [ NCBI-GEO ]   TGM5 [ EBI - ARRAY_EXPRESS ]   TGM5 [ SEEK ]   TGM5 [ MEM ]
Gene Expression Viewer (FireBrowse)TGM5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9333
GTEX Portal (Tissue expression)TGM5
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43548   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43548  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43548
Splice isoforms : SwissVarO43548
Catalytic activity : Enzyme2.3.2.13 [ Enzyme-Expasy ]   2.3.2.132.3.2.13 [ IntEnz-EBI ]   2.3.2.13 [ BRENDA ]   2.3.2.13 [ KEGG ]   
PhosPhoSitePlusO43548
Domaine pattern : Prosite (Expaxy)TRANSGLUTAMINASES (PS00547)   
Domains : Interpro (EBI)Gln_gamma-glutamylTfrase_euk    Ig-like_fold    Ig_E-set    Transglutaminase-like    Transglutaminase_C    Transglutaminase_CS    Transglutaminase_N   
Domain families : Pfam (Sanger)Transglut_C (PF00927)    Transglut_core (PF01841)    Transglut_N (PF00868)   
Domain families : Pfam (NCBI)pfam00927    pfam01841    pfam00868   
Domain families : Smart (EMBL)TGc (SM00460)  
Conserved Domain (NCBI)TGM5
DMDM Disease mutations9333
Blocks (Seattle)TGM5
SuperfamilyO43548
Human Protein AtlasENSG00000104055
Peptide AtlasO43548
HPRD11949
IPIIPI00873911   IPI00218650   IPI00012876   
Protein Interaction databases
DIP (DOE-UCLA)O43548
IntAct (EBI)O43548
FunCoupENSG00000104055
BioGRIDTGM5
STRING (EMBL)TGM5
ZODIACTGM5
Ontologies - Pathways
QuickGOO43548
Ontology : AmiGOprotein-glutamine gamma-glutamyltransferase activity  cytoplasm  cellular protein modification process  epidermis development  peptide cross-linking  metal ion binding  
Ontology : EGO-EBIprotein-glutamine gamma-glutamyltransferase activity  cytoplasm  cellular protein modification process  epidermis development  peptide cross-linking  metal ion binding  
NDEx NetworkTGM5
Atlas of Cancer Signalling NetworkTGM5
Wikipedia pathwaysTGM5
Orthology - Evolution
OrthoDB9333
GeneTree (enSembl)ENSG00000104055
Phylogenetic Trees/Animal Genes : TreeFamTGM5
HOVERGENO43548
HOGENOMO43548
Homologs : HomoloGeneTGM5
Homology/Alignments : Family Browser (UCSC)TGM5
Gene fusions - Rearrangements
Fusion : MitelmanCASC4/TGM5 [15q15.3/15q15.2]  [t(15;15)(q15;q15)]  
Fusion : MitelmanUBR1/TGM5 [15q15.2/15q15.2]  [t(15;15)(q15;q15)]  
Fusion: TCGACASC4 15q15.3 TGM5 15q15.2 BRCA
Fusion: TCGAUBR1 15q15.2 TGM5 15q15.2 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTGM5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TGM5
dbVarTGM5
ClinVarTGM5
1000_GenomesTGM5 
Exome Variant ServerTGM5
ExAC (Exome Aggregation Consortium)TGM5 (select the gene name)
Genetic variants : HAPMAP9333
Genomic Variants (DGV)TGM5 [DGVbeta]
DECIPHER (Syndromes)15:43524793-43559055  ENSG00000104055
CONAN: Copy Number AnalysisTGM5 
Mutations
ICGC Data PortalTGM5 
TCGA Data PortalTGM5 
Broad Tumor PortalTGM5
OASIS PortalTGM5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTGM5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTGM5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TGM5
DgiDB (Drug Gene Interaction Database)TGM5
DoCM (Curated mutations)TGM5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TGM5 (select a term)
intoGenTGM5
Cancer3DTGM5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603805    609796   
Orphanet20068   
MedgenTGM5
Genetic Testing Registry TGM5
NextProtO43548 [Medical]
TSGene9333
GENETestsTGM5
Huge Navigator TGM5 [HugePedia]
snp3D : Map Gene to Disease9333
BioCentury BCIQTGM5
ClinGenTGM5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9333
Chemical/Pharm GKB GenePA36494
Clinical trialTGM5
Miscellaneous
canSAR (ICR)TGM5 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTGM5
EVEXTGM5
GoPubMedTGM5
iHOPTGM5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:30:58 CET 2017

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