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TGM6 (transglutaminase 6)

Identity

Alias_namesTGM3L
transglutaminase 3-like
Alias_symbol (synonym)dJ734P14.3
TGY
SCA35
Other aliasTG6
HGNC (Hugo) TGM6
LocusID (NCBI) 343641
Atlas_Id 74661
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 2380908 and ends at 2432753 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TGM6   16255
Cards
Entrez_Gene (NCBI)TGM6  343641  transglutaminase 6
AliasesSCA35; TG6; TGM3L; TGY; 
dJ734P14.3
GeneCards (Weizmann)TGM6
Ensembl hg19 (Hinxton)ENSG00000166948 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166948 [Gene_View]  chr20:2380908-2432753 [Contig_View]  TGM6 [Vega]
ICGC DataPortalENSG00000166948
TCGA cBioPortalTGM6
AceView (NCBI)TGM6
Genatlas (Paris)TGM6
WikiGenes343641
SOURCE (Princeton)TGM6
Genetics Home Reference (NIH)TGM6
Genomic and cartography
GoldenPath hg38 (UCSC)TGM6  -     chr20:2380908-2432753 +  20p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TGM6  -     20p13   [Description]    (hg19-Feb_2009)
EnsemblTGM6 - 20p13 [CytoView hg19]  TGM6 - 20p13 [CytoView hg38]
Mapping of homologs : NCBITGM6 [Mapview hg19]  TGM6 [Mapview hg38]
OMIM613900   613908   
Gene and transcription
Genbank (Entrez)AF540969 AF540970 BC166680
RefSeq transcript (Entrez)NM_001254734 NM_198994
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TGM6
Cluster EST : UnigeneHs.452039 [ NCBI ]
CGAP (NCI)Hs.452039
Alternative Splicing GalleryENSG00000166948
Gene ExpressionTGM6 [ NCBI-GEO ]   TGM6 [ EBI - ARRAY_EXPRESS ]   TGM6 [ SEEK ]   TGM6 [ MEM ]
Gene Expression Viewer (FireBrowse)TGM6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)343641
GTEX Portal (Tissue expression)TGM6
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95932   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95932  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95932
Splice isoforms : SwissVarO95932
Catalytic activity : Enzyme2.3.2.13 [ Enzyme-Expasy ]   2.3.2.132.3.2.13 [ IntEnz-EBI ]   2.3.2.13 [ BRENDA ]   2.3.2.13 [ KEGG ]   
PhosPhoSitePlusO95932
Domaine pattern : Prosite (Expaxy)TRANSGLUTAMINASES (PS00547)   
Domains : Interpro (EBI)Gln_gamma-glutamylTfrase_euk    Ig-like_fold    Ig_E-set    Transglutaminase-like    Transglutaminase_AS    Transglutaminase_C    Transglutaminase_N   
Domain families : Pfam (Sanger)Transglut_C (PF00927)    Transglut_core (PF01841)    Transglut_N (PF00868)   
Domain families : Pfam (NCBI)pfam00927    pfam01841    pfam00868   
Domain families : Smart (EMBL)TGc (SM00460)  
Conserved Domain (NCBI)TGM6
DMDM Disease mutations343641
Blocks (Seattle)TGM6
SuperfamilyO95932
Human Protein AtlasENSG00000166948
Peptide AtlasO95932
HPRD15495
IPIIPI00419037   IPI00031372   
Protein Interaction databases
DIP (DOE-UCLA)O95932
IntAct (EBI)O95932
FunCoupENSG00000166948
BioGRIDTGM6
STRING (EMBL)TGM6
ZODIACTGM6
Ontologies - Pathways
QuickGOO95932
Ontology : AmiGOprotein-glutamine gamma-glutamyltransferase activity  cytoplasm  peptide cross-linking  metal ion binding  
Ontology : EGO-EBIprotein-glutamine gamma-glutamyltransferase activity  cytoplasm  peptide cross-linking  metal ion binding  
NDEx NetworkTGM6
Atlas of Cancer Signalling NetworkTGM6
Wikipedia pathwaysTGM6
Orthology - Evolution
OrthoDB343641
GeneTree (enSembl)ENSG00000166948
Phylogenetic Trees/Animal Genes : TreeFamTGM6
HOVERGENO95932
HOGENOMO95932
Homologs : HomoloGeneTGM6
Homology/Alignments : Family Browser (UCSC)TGM6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTGM6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TGM6
dbVarTGM6
ClinVarTGM6
1000_GenomesTGM6 
Exome Variant ServerTGM6
ExAC (Exome Aggregation Consortium)TGM6 (select the gene name)
Genetic variants : HAPMAP343641
Genomic Variants (DGV)TGM6 [DGVbeta]
DECIPHERTGM6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTGM6 
Mutations
ICGC Data PortalTGM6 
TCGA Data PortalTGM6 
Broad Tumor PortalTGM6
OASIS PortalTGM6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTGM6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTGM6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TGM6
DgiDB (Drug Gene Interaction Database)TGM6
DoCM (Curated mutations)TGM6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TGM6 (select a term)
intoGenTGM6
Cancer3DTGM6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613900    613908   
Orphanet20354    21659   
MedgenTGM6
Genetic Testing Registry TGM6
NextProtO95932 [Medical]
TSGene343641
GENETestsTGM6
Target ValidationTGM6
Huge Navigator TGM6 [HugePedia]
snp3D : Map Gene to Disease343641
BioCentury BCIQTGM6
ClinGenTGM6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD343641
Chemical/Pharm GKB GenePA38098
Clinical trialTGM6
Miscellaneous
canSAR (ICR)TGM6 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTGM6
EVEXTGM6
GoPubMedTGM6
iHOPTGM6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:41:21 CEST 2017

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