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THADA (THADA, armadillo repeat containing)

Identity

Alias_namesthyroid adenoma associated
Alias_symbol (synonym)FLJ21877
KIAA1767
GITA
ARMC13
Other alias
HGNC (Hugo) THADA
LocusID (NCBI) 63892
Atlas_Id 46606
Location 2p21  [Link to chromosome band 2p21]
Location_base_pair Starts at 43230836 and ends at 43595974 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IGF2BP3 (7p15.3) / THADA (2p21)KIAA1429 (8q22.1) / THADA (2p21)NBAS (2p24.3) / THADA (2p21)
RPS2P32 (7p15.3) / THADA (2p21)TG (8q24.22) / THADA (2p21)THADA (2p21) / CFAP45 (1q23.2)
THADA (2p21) / DYTN (2q33.3)THADA (2p21) / EML4 (2p21)THADA (2p21) / IGF2BP3 (7p15.3)
THADA (2p21) / MAP4K3 (2p22.1)THADA (2p21) / MECOM (3q26.2)THADA (2p21) / PPARG (3p25.2)
TRA2A (7p15.3) / THADA (2p21)NBAS 2p24.3 / THADA 2p21THADA 2p21 CCDC19
THADA 2p21 / EML4 2p21THADA 2p21 / IGF2BP3 7p15.3TRA2A 7p15.3 / THADA 2p21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(1;2)(p36;p21) THADA/PRDM16
t(2;3)(p16;q26) BCL11A/MECOM
t(2;3)(p21;q26) THADA/MECOM


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)THADA   19217
Cards
Entrez_Gene (NCBI)THADA  63892  THADA, armadillo repeat containing
AliasesARMC13; GITA
GeneCards (Weizmann)THADA
Ensembl hg19 (Hinxton)ENSG00000115970 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115970 [Gene_View]  chr2:43230836-43595974 [Contig_View]  THADA [Vega]
ICGC DataPortalENSG00000115970
TCGA cBioPortalTHADA
AceView (NCBI)THADA
Genatlas (Paris)THADA
WikiGenes63892
SOURCE (Princeton)THADA
Genetics Home Reference (NIH)THADA
Genomic and cartography
GoldenPath hg38 (UCSC)THADA  -     chr2:43230836-43595974 -  2p21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)THADA  -     2p21   [Description]    (hg19-Feb_2009)
EnsemblTHADA - 2p21 [CytoView hg19]  THADA - 2p21 [CytoView hg38]
Mapping of homologs : NCBITHADA [Mapview hg19]  THADA [Mapview hg38]
OMIM611800   
Gene and transcription
Genbank (Entrez)AB051554 AF323176 AK025445 AK025530 AK126004
RefSeq transcript (Entrez)NM_001083953 NM_001271643 NM_001271644 NM_001345923 NM_001345924 NM_001345925 NM_022065
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)THADA
Cluster EST : UnigeneHs.369592 [ NCBI ]
CGAP (NCI)Hs.369592
Alternative Splicing GalleryENSG00000115970
Gene ExpressionTHADA [ NCBI-GEO ]   THADA [ EBI - ARRAY_EXPRESS ]   THADA [ SEEK ]   THADA [ MEM ]
Gene Expression Viewer (FireBrowse)THADA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)63892
GTEX Portal (Tissue expression)THADA
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6YHU6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6YHU6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6YHU6
Splice isoforms : SwissVarQ6YHU6
PhosPhoSitePlusQ6YHU6
Domains : Interpro (EBI)ARM-type_fold    DUF2428_death-receptor-like   
Domain families : Pfam (Sanger)DUF2428 (PF10350)   
Domain families : Pfam (NCBI)pfam10350   
Conserved Domain (NCBI)THADA
DMDM Disease mutations63892
Blocks (Seattle)THADA
SuperfamilyQ6YHU6
Human Protein AtlasENSG00000115970
Peptide AtlasQ6YHU6
HPRD18177
IPIIPI01019074   IPI00900350   IPI00917435   IPI00894197   IPI00412647   IPI00894544   IPI00900266   IPI00640767   IPI00894087   IPI00892620   IPI00915395   IPI01014541   
Protein Interaction databases
DIP (DOE-UCLA)Q6YHU6
IntAct (EBI)Q6YHU6
FunCoupENSG00000115970
BioGRIDTHADA
STRING (EMBL)THADA
ZODIACTHADA
Ontologies - Pathways
QuickGOQ6YHU6
Ontology : AmiGOprotein binding  
Ontology : EGO-EBIprotein binding  
NDEx NetworkTHADA
Atlas of Cancer Signalling NetworkTHADA
Wikipedia pathwaysTHADA
Orthology - Evolution
OrthoDB63892
GeneTree (enSembl)ENSG00000115970
Phylogenetic Trees/Animal Genes : TreeFamTHADA
HOVERGENQ6YHU6
HOGENOMQ6YHU6
Homologs : HomoloGeneTHADA
Homology/Alignments : Family Browser (UCSC)THADA
Gene fusions - Rearrangements
Fusion : MitelmanIGF2BP3/THADA [7p15.3/2p21]  [t(2;7)(p21;p15)]  
Fusion : MitelmanNBAS/THADA [2p24.3/2p21]  [t(2;2)(p21;p24)]  
Fusion : MitelmanRPS2P32/THADA [7p15.3/2p21]  [t(2;7)(p21;p15)]  
Fusion : MitelmanTG/THADA [8q24.22/2p21]  [t(2;8)(p21;q24)]  
Fusion : MitelmanTHADA/CFAP45 [2p21/1q23.2]  [t(1;2)(q23;p21)]  
Fusion : MitelmanTHADA/IGF2BP3 [2p21/7p15.3]  [t(2;7)(p21;p15)]  
Fusion : MitelmanTHADA/MAP4K3 [2p21/2p22.1]  [t(2;2)(p21;p22)]  
Fusion : MitelmanTRA2A/THADA [7p15.3/2p21]  [t(2;7)(p21;p15)]  
Fusion: TCGANBAS 2p24.3 THADA 2p21 BRCA
Fusion: TCGATHADA 2p21 CCDC19 BRCA
Fusion: TCGATHADA 2p21 EML4 2p21 LUSC
Fusion: TCGATHADA 2p21 IGF2BP3 7p15.3 THCA
Fusion: TCGATRA2A 7p15.3 THADA 2p21 THCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTHADA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)THADA
dbVarTHADA
ClinVarTHADA
1000_GenomesTHADA 
Exome Variant ServerTHADA
ExAC (Exome Aggregation Consortium)THADA (select the gene name)
Genetic variants : HAPMAP63892
Genomic Variants (DGV)THADA [DGVbeta]
DECIPHERTHADA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTHADA 
Mutations
ICGC Data PortalTHADA 
TCGA Data PortalTHADA 
Broad Tumor PortalTHADA
OASIS PortalTHADA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTHADA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTHADA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch THADA
DgiDB (Drug Gene Interaction Database)THADA
DoCM (Curated mutations)THADA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)THADA (select a term)
intoGenTHADA
Cancer3DTHADA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611800   
Orphanet
MedgenTHADA
Genetic Testing Registry THADA
NextProtQ6YHU6 [Medical]
TSGene63892
GENETestsTHADA
Target ValidationTHADA
Huge Navigator THADA [HugePedia]
snp3D : Map Gene to Disease63892
BioCentury BCIQTHADA
ClinGenTHADA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD63892
Chemical/Pharm GKB GenePA134882460
Clinical trialTHADA
Miscellaneous
canSAR (ICR)THADA (select the gene name)
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTHADA
EVEXTHADA
GoPubMedTHADA
iHOPTHADA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:34:53 CEST 2017

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