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THAP12 (THAP domain containing 12)

Identity

Alias_namesPRKRIR
protein-kinase
Alias_symbol (synonym)P52rIPK
DAP4
THAP0
Other alias
HGNC (Hugo) THAP12
LocusID (NCBI) 5612
Atlas_Id 56446
Location 11q13.5  [Link to chromosome band 11q13]
Location_base_pair Starts at 76349957 and ends at 76380965 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)THAP12   9440
Cards
Entrez_Gene (NCBI)THAP12  5612  THAP domain containing 12
AliasesDAP4; P52rIPK; PRKRIR; THAP0
GeneCards (Weizmann)THAP12
Ensembl hg19 (Hinxton)ENSG00000137492 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137492 [Gene_View]  chr11:76349957-76380965 [Contig_View]  THAP12 [Vega]
ICGC DataPortalENSG00000137492
TCGA cBioPortalTHAP12
AceView (NCBI)THAP12
Genatlas (Paris)THAP12
WikiGenes5612
SOURCE (Princeton)THAP12
Genetics Home Reference (NIH)THAP12
Genomic and cartography
GoldenPath hg38 (UCSC)THAP12  -     chr11:76349957-76380965 -  11q13.5   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)THAP12  -     11q13.5   [Description]    (hg19-Feb_2009)
EnsemblTHAP12 - 11q13.5 [CytoView hg19]  THAP12 - 11q13.5 [CytoView hg38]
Mapping of homologs : NCBITHAP12 [Mapview hg19]  THAP12 [Mapview hg38]
OMIM607374   
Gene and transcription
Genbank (Entrez)AA765102 AF007393 AF081567 AK001522 AK291843
RefSeq transcript (Entrez)NM_004705
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)THAP12
Cluster EST : UnigeneHs.503315 [ NCBI ]
CGAP (NCI)Hs.503315
Alternative Splicing GalleryENSG00000137492
Gene ExpressionTHAP12 [ NCBI-GEO ]   THAP12 [ EBI - ARRAY_EXPRESS ]   THAP12 [ SEEK ]   THAP12 [ MEM ]
Gene Expression Viewer (FireBrowse)THAP12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5612
GTEX Portal (Tissue expression)THAP12
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43422   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43422  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43422
Splice isoforms : SwissVarO43422
PhosPhoSitePlusO43422
Domaine pattern : Prosite (Expaxy)ZF_THAP (PS50950)   
Domains : Interpro (EBI)DUF4371    HATC_C_dom    RNaseH-like_dom    Znf_C2CH   
Domain families : Pfam (Sanger)Dimer_Tnp_hAT (PF05699)    DUF4371 (PF14291)    THAP (PF05485)   
Domain families : Pfam (NCBI)pfam05699    pfam14291    pfam05485   
Domain families : Smart (EMBL)DM3 (SM00692)  THAP (SM00980)  
Conserved Domain (NCBI)THAP12
DMDM Disease mutations5612
Blocks (Seattle)THAP12
SuperfamilyO43422
Human Protein AtlasENSG00000137492
Peptide AtlasO43422
HPRD09567
IPIIPI00012438   IPI00219175   IPI00981277   IPI00978056   
Protein Interaction databases
DIP (DOE-UCLA)O43422
IntAct (EBI)O43422
FunCoupENSG00000137492
BioGRIDTHAP12
STRING (EMBL)THAP12
ZODIACTHAP12
Ontologies - Pathways
QuickGOO43422
Ontology : AmiGORNA polymerase II transcription factor activity, sequence-specific DNA binding  DNA binding  protein binding  nucleoplasm  cytoplasm  regulation of transcription from RNA polymerase II promoter  response to stress  signal transduction  negative regulation of cell proliferation  metal ion binding  protein dimerization activity  
Ontology : EGO-EBIRNA polymerase II transcription factor activity, sequence-specific DNA binding  DNA binding  protein binding  nucleoplasm  cytoplasm  regulation of transcription from RNA polymerase II promoter  response to stress  signal transduction  negative regulation of cell proliferation  metal ion binding  protein dimerization activity  
NDEx NetworkTHAP12
Atlas of Cancer Signalling NetworkTHAP12
Wikipedia pathwaysTHAP12
Orthology - Evolution
OrthoDB5612
GeneTree (enSembl)ENSG00000137492
Phylogenetic Trees/Animal Genes : TreeFamTHAP12
HOVERGENO43422
HOGENOMO43422
Homologs : HomoloGeneTHAP12
Homology/Alignments : Family Browser (UCSC)THAP12
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTHAP12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)THAP12
dbVarTHAP12
ClinVarTHAP12
1000_GenomesTHAP12 
Exome Variant ServerTHAP12
ExAC (Exome Aggregation Consortium)THAP12 (select the gene name)
Genetic variants : HAPMAP5612
Genomic Variants (DGV)THAP12 [DGVbeta]
DECIPHERTHAP12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTHAP12 
Mutations
ICGC Data PortalTHAP12 
TCGA Data PortalTHAP12 
Broad Tumor PortalTHAP12
OASIS PortalTHAP12 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDTHAP12
BioMutasearch THAP12
DgiDB (Drug Gene Interaction Database)THAP12
DoCM (Curated mutations)THAP12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)THAP12 (select a term)
intoGenTHAP12
Cancer3DTHAP12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607374   
Orphanet
MedgenTHAP12
Genetic Testing Registry THAP12
NextProtO43422 [Medical]
TSGene5612
GENETestsTHAP12
Target ValidationTHAP12
Huge Navigator THAP12 [HugePedia]
snp3D : Map Gene to Disease5612
BioCentury BCIQTHAP12
ClinGenTHAP12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5612
Chemical/Pharm GKB GenePA33781
Clinical trialTHAP12
Miscellaneous
canSAR (ICR)THAP12 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTHAP12
EVEXTHAP12
GoPubMedTHAP12
iHOPTHAP12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:34:54 CEST 2017

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