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THAP2 (THAP domain containing 2)

Identity

Alias (NCBI)-
HGNC (Hugo) THAP2
HGNC Alias symbDKFZP564I0422
HGNC Previous nameTHAP domain containing, apoptosis associated protein 2
LocusID (NCBI) 83591
Atlas_Id 74665
Location 12q21.1  [Link to chromosome band 12q21]
Location_base_pair Starts at 71664301 and ends at 71680643 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
THAP2 (12q21.1) / GRIP1 (12q14.3)TMTC3 (12q21.32) / THAP2 (12q21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)THAP2   20854
Cards
Entrez_Gene (NCBI)THAP2    THAP domain containing 2
Aliases
GeneCards (Weizmann)THAP2
Ensembl hg19 (Hinxton)ENSG00000173451 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173451 [Gene_View]  ENSG00000173451 [Sequence]  chr12:71664301-71680643 [Contig_View]  THAP2 [Vega]
ICGC DataPortalENSG00000173451
TCGA cBioPortalTHAP2
AceView (NCBI)THAP2
Genatlas (Paris)THAP2
SOURCE (Princeton)THAP2
Genetics Home Reference (NIH)THAP2
Genomic and cartography
GoldenPath hg38 (UCSC)THAP2  -     chr12:71664301-71680643 +  12q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)THAP2  -     12q21.1   [Description]    (hg19-Feb_2009)
GoldenPathTHAP2 - 12q21.1 [CytoView hg19]  THAP2 - 12q21.1 [CytoView hg38]
ImmunoBaseENSG00000173451
Genome Data Viewer NCBITHAP2 [Mapview hg19]  
OMIM612531   
Gene and transcription
Genbank (Entrez)AK313452 AL136607 BC008358 BP371303 CR533485
RefSeq transcript (Entrez)NM_031435
Consensus coding sequences : CCDS (NCBI)THAP2
Gene ExpressionTHAP2 [ NCBI-GEO ]   THAP2 [ EBI - ARRAY_EXPRESS ]   THAP2 [ SEEK ]   THAP2 [ MEM ]
Gene Expression Viewer (FireBrowse)THAP2 [ Firebrowse - Broad ]
GenevisibleExpression of THAP2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83591
GTEX Portal (Tissue expression)THAP2
Human Protein AtlasENSG00000173451-THAP2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H0W7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H0W7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H0W7
PhosPhoSitePlusQ9H0W7
Domaine pattern : Prosite (Expaxy)ZF_THAP (PS50950)   
Domains : Interpro (EBI)THAP2    THAP_Znf    THAP_Znf_sf   
Domain families : Pfam (Sanger)THAP (PF05485)   
Domain families : Pfam (NCBI)pfam05485   
Domain families : Smart (EMBL)DM3 (SM00692)  THAP (SM00980)  
Conserved Domain (NCBI)THAP2
PDB (RSDB)2D8R   
PDB Europe2D8R   
PDB (PDBSum)2D8R   
PDB (IMB)2D8R   
Structural Biology KnowledgeBase2D8R   
SCOP (Structural Classification of Proteins)2D8R   
CATH (Classification of proteins structures)2D8R   
SuperfamilyQ9H0W7
AlphaFold pdb e-kbQ9H0W7   
Human Protein Atlas [tissue]ENSG00000173451-THAP2 [tissue]
HPRD10896
Protein Interaction databases
DIP (DOE-UCLA)Q9H0W7
IntAct (EBI)Q9H0W7
BioGRIDTHAP2
STRING (EMBL)THAP2
ZODIACTHAP2
Ontologies - Pathways
QuickGOQ9H0W7
Ontology : AmiGODNA binding  nucleus  nucleolus  metal ion binding  
Ontology : EGO-EBIDNA binding  nucleus  nucleolus  metal ion binding  
NDEx NetworkTHAP2
Atlas of Cancer Signalling NetworkTHAP2
Wikipedia pathwaysTHAP2
Orthology - Evolution
OrthoDB83591
GeneTree (enSembl)ENSG00000173451
Phylogenetic Trees/Animal Genes : TreeFamTHAP2
Homologs : HomoloGeneTHAP2
Homology/Alignments : Family Browser (UCSC)THAP2
Gene fusions - Rearrangements
Fusion : QuiverTHAP2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTHAP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)THAP2
dbVarTHAP2
ClinVarTHAP2
MonarchTHAP2
1000_GenomesTHAP2 
Exome Variant ServerTHAP2
GNOMAD BrowserENSG00000173451
Varsome BrowserTHAP2
ACMGTHAP2 variants
VarityQ9H0W7
Genomic Variants (DGV)THAP2 [DGVbeta]
DECIPHERTHAP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTHAP2 
Mutations
ICGC Data PortalTHAP2 
TCGA Data PortalTHAP2 
Broad Tumor PortalTHAP2
OASIS PortalTHAP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTHAP2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTHAP2
Mutations and Diseases : HGMDTHAP2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTHAP2
DgiDB (Drug Gene Interaction Database)THAP2
DoCM (Curated mutations)THAP2
CIViC (Clinical Interpretations of Variants in Cancer)THAP2
Cancer3DTHAP2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612531   
Orphanet
DisGeNETTHAP2
MedgenTHAP2
Genetic Testing Registry THAP2
NextProtQ9H0W7 [Medical]
GENETestsTHAP2
Target ValidationTHAP2
Huge Navigator THAP2 [HugePedia]
ClinGenTHAP2
Clinical trials, drugs, therapy
MyCancerGenomeTHAP2
Protein Interactions : CTDTHAP2
Pharm GKB GenePA134886354
PharosQ9H0W7
Clinical trialTHAP2
Miscellaneous
canSAR (ICR)THAP2
HarmonizomeTHAP2
DataMed IndexTHAP2
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTHAP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:25:25 CEST 2021

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