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THAP7 (THAP domain containing 7)

Identity

Alias (NCBI)-
HGNC (Hugo) THAP7
HGNC Alias symbMGC10963
LocusID (NCBI) 80764
Atlas_Id 54699
Location 22q11.21  [Link to chromosome band 22q11]
Location_base_pair Starts at 20999104 and ends at 21002118 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
THAP7 (22q11.21) / PRODH (22q11.21)THAP7 (22q11.21) / THAP7 (22q11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)THAP7   23190
Cards
Entrez_Gene (NCBI)THAP7    THAP domain containing 7
Aliases
GeneCards (Weizmann)THAP7
Ensembl hg19 (Hinxton)ENSG00000184436 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184436 [Gene_View]  ENSG00000184436 [Sequence]  chr22:20999104-21002118 [Contig_View]  THAP7 [Vega]
ICGC DataPortalENSG00000184436
TCGA cBioPortalTHAP7
AceView (NCBI)THAP7
Genatlas (Paris)THAP7
SOURCE (Princeton)THAP7
Genetics Home Reference (NIH)THAP7
Genomic and cartography
GoldenPath hg38 (UCSC)THAP7  -     chr22:20999104-21002118 -  22q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)THAP7  -     22q11.21   [Description]    (hg19-Feb_2009)
GoldenPathTHAP7 - 22q11.21 [CytoView hg19]  THAP7 - 22q11.21 [CytoView hg38]
ImmunoBaseENSG00000184436
Genome Data Viewer NCBITHAP7 [Mapview hg19]  
OMIM609518   
Gene and transcription
Genbank (Entrez)AK024609 AK025906 AK300715 AK315457 BC004346
RefSeq transcript (Entrez)NM_001008695 NM_001008696 NM_030573
Consensus coding sequences : CCDS (NCBI)THAP7
Gene ExpressionTHAP7 [ NCBI-GEO ]   THAP7 [ EBI - ARRAY_EXPRESS ]   THAP7 [ SEEK ]   THAP7 [ MEM ]
Gene Expression Viewer (FireBrowse)THAP7 [ Firebrowse - Broad ]
GenevisibleExpression of THAP7 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80764
GTEX Portal (Tissue expression)THAP7
Human Protein AtlasENSG00000184436-THAP7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BT49   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BT49  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BT49
PhosPhoSitePlusQ9BT49
Domaine pattern : Prosite (Expaxy)ZF_THAP (PS50950)   
Domains : Interpro (EBI)THAP7    THAP_Znf    THAP_Znf_sf   
Domain families : Pfam (Sanger)THAP (PF05485)   
Domain families : Pfam (NCBI)pfam05485   
Domain families : Smart (EMBL)DM3 (SM00692)  THAP (SM00980)  
Conserved Domain (NCBI)THAP7
SuperfamilyQ9BT49
AlphaFold pdb e-kbQ9BT49   
Human Protein Atlas [tissue]ENSG00000184436-THAP7 [tissue]
HPRD15500
Protein Interaction databases
DIP (DOE-UCLA)Q9BT49
IntAct (EBI)Q9BT49
BioGRIDTHAP7
STRING (EMBL)THAP7
ZODIACTHAP7
Ontologies - Pathways
QuickGOQ9BT49
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  transcription corepressor binding  DNA binding  protein binding  nucleus  nucleoplasm  chromosome  regulation of transcription, DNA-templated  nuclear speck  nucleosomal histone binding  nuclear membrane  methylated histone binding  negative regulation of histone acetylation  identical protein binding  histone deacetylase binding  intracellular membrane-bounded organelle  negative regulation of transcription, DNA-templated  metal ion binding  protein N-terminus binding  lysine-acetylated histone binding  C2H2 zinc finger domain binding  phosphorylated histone binding  general transcription initiation factor binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  transcription corepressor binding  DNA binding  protein binding  nucleus  nucleoplasm  chromosome  regulation of transcription, DNA-templated  nuclear speck  nucleosomal histone binding  nuclear membrane  methylated histone binding  negative regulation of histone acetylation  identical protein binding  histone deacetylase binding  intracellular membrane-bounded organelle  negative regulation of transcription, DNA-templated  metal ion binding  protein N-terminus binding  lysine-acetylated histone binding  C2H2 zinc finger domain binding  phosphorylated histone binding  general transcription initiation factor binding  
NDEx NetworkTHAP7
Atlas of Cancer Signalling NetworkTHAP7
Wikipedia pathwaysTHAP7
Orthology - Evolution
OrthoDB80764
GeneTree (enSembl)ENSG00000184436
Phylogenetic Trees/Animal Genes : TreeFamTHAP7
Homologs : HomoloGeneTHAP7
Homology/Alignments : Family Browser (UCSC)THAP7
Gene fusions - Rearrangements
Fusion : MitelmanTHAP7/PRODH [22q11.21/22q11.21]  
Fusion : QuiverTHAP7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTHAP7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)THAP7
dbVarTHAP7
ClinVarTHAP7
MonarchTHAP7
1000_GenomesTHAP7 
Exome Variant ServerTHAP7
GNOMAD BrowserENSG00000184436
Varsome BrowserTHAP7
ACMGTHAP7 variants
VarityQ9BT49
Genomic Variants (DGV)THAP7 [DGVbeta]
DECIPHERTHAP7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTHAP7 
Mutations
ICGC Data PortalTHAP7 
TCGA Data PortalTHAP7 
Broad Tumor PortalTHAP7
OASIS PortalTHAP7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTHAP7  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTHAP7
Mutations and Diseases : HGMDTHAP7
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTHAP7
DgiDB (Drug Gene Interaction Database)THAP7
DoCM (Curated mutations)THAP7
CIViC (Clinical Interpretations of Variants in Cancer)THAP7
Cancer3DTHAP7
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609518   
Orphanet
DisGeNETTHAP7
MedgenTHAP7
Genetic Testing Registry THAP7
NextProtQ9BT49 [Medical]
GENETestsTHAP7
Target ValidationTHAP7
Huge Navigator THAP7 [HugePedia]
ClinGenTHAP7
Clinical trials, drugs, therapy
MyCancerGenomeTHAP7
Protein Interactions : CTDTHAP7
Pharm GKB GenePA134964580
PharosQ9BT49
Clinical trialTHAP7
Miscellaneous
canSAR (ICR)THAP7
HarmonizomeTHAP7
DataMed IndexTHAP7
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTHAP7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:34:59 CEST 2021

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