Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

THAP7 (THAP domain containing 7)

Identity

Alias_symbol (synonym)MGC10963
Other alias-
HGNC (Hugo) THAP7
LocusID (NCBI) 80764
Atlas_Id 54699
Location 22q11.21  [Link to chromosome band 22q11]
Location_base_pair Starts at 20999772 and ends at 21002115 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
THAP7 (22q11.21) / PRODH (22q11.21)THAP7 (22q11.21) / THAP7 (22q11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)THAP7   23190
Cards
Entrez_Gene (NCBI)THAP7  80764  THAP domain containing 7
Aliases
GeneCards (Weizmann)THAP7
Ensembl hg19 (Hinxton)ENSG00000184436 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184436 [Gene_View]  chr22:20999772-21002115 [Contig_View]  THAP7 [Vega]
ICGC DataPortalENSG00000184436
TCGA cBioPortalTHAP7
AceView (NCBI)THAP7
Genatlas (Paris)THAP7
WikiGenes80764
SOURCE (Princeton)THAP7
Genetics Home Reference (NIH)THAP7
Genomic and cartography
GoldenPath hg38 (UCSC)THAP7  -     chr22:20999772-21002115 -  22q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)THAP7  -     22q11.21   [Description]    (hg19-Feb_2009)
EnsemblTHAP7 - 22q11.21 [CytoView hg19]  THAP7 - 22q11.21 [CytoView hg38]
Mapping of homologs : NCBITHAP7 [Mapview hg19]  THAP7 [Mapview hg38]
OMIM609518   
Gene and transcription
Genbank (Entrez)AK024609 AK025906 AK300715 AK315457 BC004346
RefSeq transcript (Entrez)NM_001008695 NM_001008696 NM_030573
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)THAP7
Cluster EST : UnigeneHs.512756 [ NCBI ]
CGAP (NCI)Hs.512756
Alternative Splicing GalleryENSG00000184436
Gene ExpressionTHAP7 [ NCBI-GEO ]   THAP7 [ EBI - ARRAY_EXPRESS ]   THAP7 [ SEEK ]   THAP7 [ MEM ]
Gene Expression Viewer (FireBrowse)THAP7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80764
GTEX Portal (Tissue expression)THAP7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BT49   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BT49  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BT49
Splice isoforms : SwissVarQ9BT49
PhosPhoSitePlusQ9BT49
Domaine pattern : Prosite (Expaxy)ZF_THAP (PS50950)   
Domains : Interpro (EBI)THAP7    Znf_C2CH   
Domain families : Pfam (Sanger)THAP (PF05485)   
Domain families : Pfam (NCBI)pfam05485   
Domain families : Smart (EMBL)DM3 (SM00692)  THAP (SM00980)  
Conserved Domain (NCBI)THAP7
DMDM Disease mutations80764
Blocks (Seattle)THAP7
SuperfamilyQ9BT49
Human Protein AtlasENSG00000184436
Peptide AtlasQ9BT49
HPRD15500
IPIIPI00182632   IPI00914055   
Protein Interaction databases
DIP (DOE-UCLA)Q9BT49
IntAct (EBI)Q9BT49
FunCoupENSG00000184436
BioGRIDTHAP7
STRING (EMBL)THAP7
ZODIACTHAP7
Ontologies - Pathways
QuickGOQ9BT49
Ontology : AmiGODNA binding  protein binding  nucleus  chromosome  transcription, DNA-templated  nuclear speck  nuclear membrane  identical protein binding  intracellular membrane-bounded organelle  negative regulation of transcription, DNA-templated  metal ion binding  protein N-terminus binding  C2H2 zinc finger domain binding  
Ontology : EGO-EBIDNA binding  protein binding  nucleus  chromosome  transcription, DNA-templated  nuclear speck  nuclear membrane  identical protein binding  intracellular membrane-bounded organelle  negative regulation of transcription, DNA-templated  metal ion binding  protein N-terminus binding  C2H2 zinc finger domain binding  
NDEx NetworkTHAP7
Atlas of Cancer Signalling NetworkTHAP7
Wikipedia pathwaysTHAP7
Orthology - Evolution
OrthoDB80764
GeneTree (enSembl)ENSG00000184436
Phylogenetic Trees/Animal Genes : TreeFamTHAP7
HOVERGENQ9BT49
HOGENOMQ9BT49
Homologs : HomoloGeneTHAP7
Homology/Alignments : Family Browser (UCSC)THAP7
Gene fusions - Rearrangements
Fusion : MitelmanTHAP7/PRODH [22q11.21/22q11.21]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTHAP7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)THAP7
dbVarTHAP7
ClinVarTHAP7
1000_GenomesTHAP7 
Exome Variant ServerTHAP7
ExAC (Exome Aggregation Consortium)THAP7 (select the gene name)
Genetic variants : HAPMAP80764
Genomic Variants (DGV)THAP7 [DGVbeta]
DECIPHERTHAP7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTHAP7 
Mutations
ICGC Data PortalTHAP7 
TCGA Data PortalTHAP7 
Broad Tumor PortalTHAP7
OASIS PortalTHAP7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTHAP7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTHAP7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch THAP7
DgiDB (Drug Gene Interaction Database)THAP7
DoCM (Curated mutations)THAP7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)THAP7 (select a term)
intoGenTHAP7
Cancer3DTHAP7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609518   
Orphanet
MedgenTHAP7
Genetic Testing Registry THAP7
NextProtQ9BT49 [Medical]
TSGene80764
GENETestsTHAP7
Huge Navigator THAP7 [HugePedia]
snp3D : Map Gene to Disease80764
BioCentury BCIQTHAP7
ClinGenTHAP7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80764
Chemical/Pharm GKB GenePA134964580
Clinical trialTHAP7
Miscellaneous
canSAR (ICR)THAP7 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTHAP7
EVEXTHAP7
GoPubMedTHAP7
iHOPTHAP7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:40:54 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.