Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 117145
MIM: 606388
HGNC: 17947
Ensembl: ENSG00000159445
Variants:
dbSNP: 117145
ClinVar: 117145
TCGA: ENSG00000159445
COSMIC: THEM4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000159445 | ENST00000368814 | Q5T1C6 |
| ENSG00000159445 | ENST00000471464 | F6XC58 |
| ENSG00000159445 | ENST00000489410 | E9PLJ7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38994770 | 2024 | Overview of carboxyl‑terminal modulator protein 1 and its importance in various metabolic regulations (Review). | 0 |
| 38994770 | 2024 | Overview of carboxyl‑terminal modulator protein 1 and its importance in various metabolic regulations (Review). | 0 |
| 36400965 | 2023 | Carboxyl-terminal modulator protein facilitates tumor metastasis in triple-negative breast cancer. | 4 |
| 36400965 | 2023 | Carboxyl-terminal modulator protein facilitates tumor metastasis in triple-negative breast cancer. | 4 |
| 32654229 | 2021 | Enolase-phosphatase 1 acts as an oncogenic driver in glioma. | 5 |
| 32654229 | 2021 | Enolase-phosphatase 1 acts as an oncogenic driver in glioma. | 5 |
| 27447863 | 2017 | CTMP, a predictive biomarker for trastuzumab resistance in HER2-enriched breast cancer patient. | 11 |
| 27447863 | 2017 | CTMP, a predictive biomarker for trastuzumab resistance in HER2-enriched breast cancer patient. | 11 |
| 27328758 | 2016 | Carboxyl-Terminal Modulator Protein Positively Acts as an Oncogenic Driver in Head and Neck Squamous Cell Carcinoma via Regulating Akt phosphorylation. | 10 |
| 27328758 | 2016 | Carboxyl-Terminal Modulator Protein Positively Acts as an Oncogenic Driver in Head and Neck Squamous Cell Carcinoma via Regulating Akt phosphorylation. | 10 |
| 22200884 | 2012 | Carboxyl-terminal modulator protein induces apoptosis by regulating mitochondrial function in lung cancer cells. | 5 |
| 22200884 | 2012 | Carboxyl-terminal modulator protein induces apoptosis by regulating mitochondrial function in lung cancer cells. | 5 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 19168129 | 2009 | Carboxy-Terminal Modulator Protein (CTMP) is a mitochondrial protein that sensitizes cells to apoptosis. | 19 |
Citation
Dessen P
THEM4 (thioesterase superfamily member 4)
Atlas Genet Cytogenet Oncol Haematol. 2008-01-01
Online version: http://atlasgeneticsoncology.org/gene/49973/them4
