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THEM5 (thioesterase superfamily member 5)

Identity

Alias_symbol (synonym)FLJ37964
Other aliasACOT15
HGNC (Hugo) THEM5
LocusID (NCBI) 284486
Atlas_Id 74675
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 151847101 and ends at 151853697 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)THEM5   26755
Cards
Entrez_Gene (NCBI)THEM5  284486  thioesterase superfamily member 5
AliasesACOT15
GeneCards (Weizmann)THEM5
Ensembl hg19 (Hinxton)ENSG00000196407 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196407 [Gene_View]  chr1:151847101-151853697 [Contig_View]  THEM5 [Vega]
ICGC DataPortalENSG00000196407
TCGA cBioPortalTHEM5
AceView (NCBI)THEM5
Genatlas (Paris)THEM5
WikiGenes284486
SOURCE (Princeton)THEM5
Genetics Home Reference (NIH)THEM5
Genomic and cartography
GoldenPath hg38 (UCSC)THEM5  -     chr1:151847101-151853697 -  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)THEM5  -     1q21.3   [Description]    (hg19-Feb_2009)
EnsemblTHEM5 - 1q21.3 [CytoView hg19]  THEM5 - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBITHEM5 [Mapview hg19]  THEM5 [Mapview hg38]
OMIM615653   
Gene and transcription
Genbank (Entrez)AK095283 BC101610 BC112239 HQ258137
RefSeq transcript (Entrez)NM_182578
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)THEM5
Cluster EST : UnigeneHs.132648 [ NCBI ]
CGAP (NCI)Hs.132648
Alternative Splicing GalleryENSG00000196407
Gene ExpressionTHEM5 [ NCBI-GEO ]   THEM5 [ EBI - ARRAY_EXPRESS ]   THEM5 [ SEEK ]   THEM5 [ MEM ]
Gene Expression Viewer (FireBrowse)THEM5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)284486
GTEX Portal (Tissue expression)THEM5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N1Q8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N1Q8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N1Q8
Splice isoforms : SwissVarQ8N1Q8
Catalytic activity : Enzyme3.1.2.2 [ Enzyme-Expasy ]   3.1.2.23.1.2.2 [ IntEnz-EBI ]   3.1.2.2 [ BRENDA ]   3.1.2.2 [ KEGG ]   
PhosPhoSitePlusQ8N1Q8
Domains : Interpro (EBI)HotDog_dom    Thioestr_dom   
Domain families : Pfam (Sanger)4HBT (PF03061)   
Domain families : Pfam (NCBI)pfam03061   
Conserved Domain (NCBI)THEM5
DMDM Disease mutations284486
Blocks (Seattle)THEM5
PDB (SRS)4AE7   
PDB (PDBSum)4AE7   
PDB (IMB)4AE7   
PDB (RSDB)4AE7   
Structural Biology KnowledgeBase4AE7   
SCOP (Structural Classification of Proteins)4AE7   
CATH (Classification of proteins structures)4AE7   
SuperfamilyQ8N1Q8
Human Protein AtlasENSG00000196407
Peptide AtlasQ8N1Q8
HPRD08233
IPIIPI00295905   IPI00513713   
Protein Interaction databases
DIP (DOE-UCLA)Q8N1Q8
IntAct (EBI)Q8N1Q8
FunCoupENSG00000196407
BioGRIDTHEM5
STRING (EMBL)THEM5
ZODIACTHEM5
Ontologies - Pathways
QuickGOQ8N1Q8
Ontology : AmiGOprotein binding  mitochondrial matrix  mitochondrial matrix  fatty acid metabolic process  palmitoyl-CoA hydrolase activity  long-chain fatty-acyl-CoA metabolic process  long-chain fatty-acyl-CoA biosynthetic process  cardiolipin acyl-chain remodeling  acyl-CoA hydrolase activity  myristoyl-CoA hydrolase activity  
Ontology : EGO-EBIprotein binding  mitochondrial matrix  mitochondrial matrix  fatty acid metabolic process  palmitoyl-CoA hydrolase activity  long-chain fatty-acyl-CoA metabolic process  long-chain fatty-acyl-CoA biosynthetic process  cardiolipin acyl-chain remodeling  acyl-CoA hydrolase activity  myristoyl-CoA hydrolase activity  
NDEx NetworkTHEM5
Atlas of Cancer Signalling NetworkTHEM5
Wikipedia pathwaysTHEM5
Orthology - Evolution
OrthoDB284486
GeneTree (enSembl)ENSG00000196407
Phylogenetic Trees/Animal Genes : TreeFamTHEM5
HOVERGENQ8N1Q8
HOGENOMQ8N1Q8
Homologs : HomoloGeneTHEM5
Homology/Alignments : Family Browser (UCSC)THEM5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTHEM5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)THEM5
dbVarTHEM5
ClinVarTHEM5
1000_GenomesTHEM5 
Exome Variant ServerTHEM5
ExAC (Exome Aggregation Consortium)THEM5 (select the gene name)
Genetic variants : HAPMAP284486
Genomic Variants (DGV)THEM5 [DGVbeta]
DECIPHERTHEM5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTHEM5 
Mutations
ICGC Data PortalTHEM5 
TCGA Data PortalTHEM5 
Broad Tumor PortalTHEM5
OASIS PortalTHEM5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTHEM5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTHEM5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch THEM5
DgiDB (Drug Gene Interaction Database)THEM5
DoCM (Curated mutations)THEM5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)THEM5 (select a term)
intoGenTHEM5
Cancer3DTHEM5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615653   
Orphanet
MedgenTHEM5
Genetic Testing Registry THEM5
NextProtQ8N1Q8 [Medical]
TSGene284486
GENETestsTHEM5
Target ValidationTHEM5
Huge Navigator THEM5 [HugePedia]
snp3D : Map Gene to Disease284486
BioCentury BCIQTHEM5
ClinGenTHEM5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD284486
Chemical/Pharm GKB GenePA142670814
Clinical trialTHEM5
Miscellaneous
canSAR (ICR)THEM5 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTHEM5
EVEXTHEM5
GoPubMedTHEM5
iHOPTHEM5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:41:24 CEST 2017

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