Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

THEM5 (thioesterase superfamily member 5)

Identity

Alias (NCBI)ACOT15
HGNC (Hugo) THEM5
HGNC Alias symbFLJ37964
LocusID (NCBI) 284486
Atlas_Id 74675
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 151847101 and ends at 151853712 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)THEM5   26755
Cards
Entrez_Gene (NCBI)THEM5    thioesterase superfamily member 5
AliasesACOT15
GeneCards (Weizmann)THEM5
Ensembl hg19 (Hinxton)ENSG00000196407 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196407 [Gene_View]  ENSG00000196407 [Sequence]  chr1:151847101-151853712 [Contig_View]  THEM5 [Vega]
ICGC DataPortalENSG00000196407
TCGA cBioPortalTHEM5
AceView (NCBI)THEM5
Genatlas (Paris)THEM5
SOURCE (Princeton)THEM5
Genetics Home Reference (NIH)THEM5
Genomic and cartography
GoldenPath hg38 (UCSC)THEM5  -     chr1:151847101-151853712 -  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)THEM5  -     1q21.3   [Description]    (hg19-Feb_2009)
GoldenPathTHEM5 - 1q21.3 [CytoView hg19]  THEM5 - 1q21.3 [CytoView hg38]
ImmunoBaseENSG00000196407
Genome Data Viewer NCBITHEM5 [Mapview hg19]  
OMIM615653   
Gene and transcription
Genbank (Entrez)AK095283 BC101610 BC112239
RefSeq transcript (Entrez)NM_182578
Consensus coding sequences : CCDS (NCBI)THEM5
Gene ExpressionTHEM5 [ NCBI-GEO ]   THEM5 [ EBI - ARRAY_EXPRESS ]   THEM5 [ SEEK ]   THEM5 [ MEM ]
Gene Expression Viewer (FireBrowse)THEM5 [ Firebrowse - Broad ]
GenevisibleExpression of THEM5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)284486
GTEX Portal (Tissue expression)THEM5
Human Protein AtlasENSG00000196407-THEM5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N1Q8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N1Q8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N1Q8
PhosPhoSitePlusQ8N1Q8
Domains : Interpro (EBI)HotDog_dom_sf    Thioestr_dom   
Domain families : Pfam (Sanger)4HBT (PF03061)   
Domain families : Pfam (NCBI)pfam03061   
Conserved Domain (NCBI)THEM5
PDB (RSDB)4AE7   
PDB Europe4AE7   
PDB (PDBSum)4AE7   
PDB (IMB)4AE7   
Structural Biology KnowledgeBase4AE7   
SCOP (Structural Classification of Proteins)4AE7   
CATH (Classification of proteins structures)4AE7   
SuperfamilyQ8N1Q8
AlphaFold pdb e-kbQ8N1Q8   
Human Protein Atlas [tissue]ENSG00000196407-THEM5 [tissue]
HPRD08233
Protein Interaction databases
DIP (DOE-UCLA)Q8N1Q8
IntAct (EBI)Q8N1Q8
BioGRIDTHEM5
STRING (EMBL)THEM5
ZODIACTHEM5
Ontologies - Pathways
QuickGOQ8N1Q8
Ontology : AmiGOprotein binding  mitochondrial matrix  mitochondrial matrix  mitochondrial matrix  fatty acid metabolic process  acyl-CoA metabolic process  palmitoyl-CoA hydrolase activity  palmitoyl-CoA hydrolase activity  long-chain fatty-acyl-CoA metabolic process  long-chain fatty-acyl-CoA metabolic process  cardiolipin acyl-chain remodeling  cardiolipin acyl-chain remodeling  myristoyl-CoA hydrolase activity  
Ontology : EGO-EBIprotein binding  mitochondrial matrix  mitochondrial matrix  mitochondrial matrix  fatty acid metabolic process  acyl-CoA metabolic process  palmitoyl-CoA hydrolase activity  palmitoyl-CoA hydrolase activity  long-chain fatty-acyl-CoA metabolic process  long-chain fatty-acyl-CoA metabolic process  cardiolipin acyl-chain remodeling  cardiolipin acyl-chain remodeling  myristoyl-CoA hydrolase activity  
NDEx NetworkTHEM5
Atlas of Cancer Signalling NetworkTHEM5
Wikipedia pathwaysTHEM5
Orthology - Evolution
OrthoDB284486
GeneTree (enSembl)ENSG00000196407
Phylogenetic Trees/Animal Genes : TreeFamTHEM5
Homologs : HomoloGeneTHEM5
Homology/Alignments : Family Browser (UCSC)THEM5
Gene fusions - Rearrangements
Fusion : QuiverTHEM5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTHEM5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)THEM5
dbVarTHEM5
ClinVarTHEM5
MonarchTHEM5
1000_GenomesTHEM5 
Exome Variant ServerTHEM5
GNOMAD BrowserENSG00000196407
Varsome BrowserTHEM5
ACMGTHEM5 variants
VarityQ8N1Q8
Genomic Variants (DGV)THEM5 [DGVbeta]
DECIPHERTHEM5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTHEM5 
Mutations
ICGC Data PortalTHEM5 
TCGA Data PortalTHEM5 
Broad Tumor PortalTHEM5
OASIS PortalTHEM5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTHEM5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTHEM5
Mutations and Diseases : HGMDTHEM5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTHEM5
DgiDB (Drug Gene Interaction Database)THEM5
DoCM (Curated mutations)THEM5
CIViC (Clinical Interpretations of Variants in Cancer)THEM5
Cancer3DTHEM5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615653   
Orphanet
DisGeNETTHEM5
MedgenTHEM5
Genetic Testing Registry THEM5
NextProtQ8N1Q8 [Medical]
GENETestsTHEM5
Target ValidationTHEM5
Huge Navigator THEM5 [HugePedia]
ClinGenTHEM5
Clinical trials, drugs, therapy
MyCancerGenomeTHEM5
Protein Interactions : CTDTHEM5
Pharm GKB GenePA142670814
PharosQ8N1Q8
Clinical trialTHEM5
Miscellaneous
canSAR (ICR)THEM5
HarmonizomeTHEM5
DataMed IndexTHEM5
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTHEM5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:25:27 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.