Identity
HGNC
LOCATION
6q22.33
LOCUSID
ALIAS
C6orf190,C6orf207,GASP,SPOT,TSEPA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 387357
MIM: 613607
HGNC: 21569
Ensembl: ENSG00000172673
Variants:
dbSNP: 387357
ClinVar: 387357
TCGA: ENSG00000172673
COSMIC: THEMIS
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32004441 | 2020 | THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells. | 74 |
| 32004441 | 2020 | THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells. | 74 |
| 28250424 | 2017 | THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1. | 47 |
| 28250424 | 2017 | THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1. | 47 |
| 27438997 | 2016 | Increased THEMIS First Exon Usage in CD4+ T-Cells Is Associated with a Genotype that Is Protective against Multiple Sclerosis. | 7 |
| 27438997 | 2016 | Increased THEMIS First Exon Usage in CD4+ T-Cells Is Associated with a Genotype that Is Protective against Multiple Sclerosis. | 7 |
| 25535246 | 2015 | A THEMIS:SHP1 complex promotes T-cell survival. | 54 |
| 25535246 | 2015 | A THEMIS:SHP1 complex promotes T-cell survival. | 54 |
| 23820479 | 2014 | THEMIS and PTPRK in celiac intestinal mucosa: coexpression in disease and after in vitro gliadin challenge. | 18 |
| 23820479 | 2014 | THEMIS and PTPRK in celiac intestinal mucosa: coexpression in disease and after in vitro gliadin challenge. | 18 |
| 23460737 | 2013 | GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development. | 41 |
| 23460737 | 2013 | GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development. | 41 |
| 22610119 | 2012 | Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. | 800 |
| 22732588 | 2012 | Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function. | 24 |
| 22610119 | 2012 | Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. | 800 |
Citation
Dessen P
THEMIS (thymocyte selection associated)
Atlas Genet Cytogenet Oncol Haematol. 2012-08-01
Online version: http://atlasgeneticsoncology.org/gene/52829/themis
