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THEMIS2 (thymocyte selection associated family member 2)

Identity

Alias_namesC1orf38
chromosome 1 open reading frame 38
Alias_symbol (synonym)ICB-1
Icb-1
Other alias
HGNC (Hugo) THEMIS2
LocusID (NCBI) 9473
Atlas_Id 46069
Location 1p35.3  [Link to chromosome band 1p35]
Location_base_pair Starts at 27872543 and ends at 27886685 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)THEMIS2   16839
Cards
Entrez_Gene (NCBI)THEMIS2  9473  thymocyte selection associated family member 2
AliasesC1orf38; ICB-1
GeneCards (Weizmann)THEMIS2
Ensembl hg19 (Hinxton)ENSG00000130775 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130775 [Gene_View]  chr1:27872543-27886685 [Contig_View]  THEMIS2 [Vega]
ICGC DataPortalENSG00000130775
TCGA cBioPortalTHEMIS2
AceView (NCBI)THEMIS2
Genatlas (Paris)THEMIS2
WikiGenes9473
SOURCE (Princeton)THEMIS2
Genetics Home Reference (NIH)THEMIS2
Genomic and cartography
GoldenPath hg38 (UCSC)THEMIS2  -     chr1:27872543-27886685 +  1p35.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)THEMIS2  -     1p35.3   [Description]    (hg19-Feb_2009)
EnsemblTHEMIS2 - 1p35.3 [CytoView hg19]  THEMIS2 - 1p35.3 [CytoView hg38]
Mapping of homologs : NCBITHEMIS2 [Mapview hg19]  THEMIS2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA477142 AB035482 AB050854 AF044896 AF323721
RefSeq transcript (Entrez)NM_001039477 NM_001105556 NM_001286113 NM_001286115 NM_004848
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)THEMIS2
Cluster EST : UnigeneHs.10649 [ NCBI ]
CGAP (NCI)Hs.10649
Alternative Splicing GalleryENSG00000130775
Gene ExpressionTHEMIS2 [ NCBI-GEO ]   THEMIS2 [ EBI - ARRAY_EXPRESS ]   THEMIS2 [ SEEK ]   THEMIS2 [ MEM ]
Gene Expression Viewer (FireBrowse)THEMIS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9473
GTEX Portal (Tissue expression)THEMIS2
Human Protein AtlasENSG00000130775-THEMIS2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5TEJ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5TEJ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5TEJ8
Splice isoforms : SwissVarQ5TEJ8
PhosPhoSitePlusQ5TEJ8
Domains : Interpro (EBI)CABIT_dom   
Domain families : Pfam (Sanger)CABIT (PF12736)   
Domain families : Pfam (NCBI)pfam12736   
Conserved Domain (NCBI)THEMIS2
DMDM Disease mutations9473
Blocks (Seattle)THEMIS2
SuperfamilyQ5TEJ8
Human Protein Atlas [tissue]ENSG00000130775-THEMIS2 [tissue]
Peptide AtlasQ5TEJ8
HPRD12728
IPIIPI00514477   IPI00003922   IPI00307376   IPI00470916   IPI00943868   IPI00943840   IPI00514107   IPI00383927   IPI00513993   
Protein Interaction databases
DIP (DOE-UCLA)Q5TEJ8
IntAct (EBI)Q5TEJ8
FunCoupENSG00000130775
BioGRIDTHEMIS2
STRING (EMBL)THEMIS2
ZODIACTHEMIS2
Ontologies - Pathways
QuickGOQ5TEJ8
Ontology : AmiGOprotein binding  nucleus  cytoplasm  inflammatory response  cell adhesion  T cell receptor signaling pathway  
Ontology : EGO-EBIprotein binding  nucleus  cytoplasm  inflammatory response  cell adhesion  T cell receptor signaling pathway  
NDEx NetworkTHEMIS2
Atlas of Cancer Signalling NetworkTHEMIS2
Wikipedia pathwaysTHEMIS2
Orthology - Evolution
OrthoDB9473
GeneTree (enSembl)ENSG00000130775
Phylogenetic Trees/Animal Genes : TreeFamTHEMIS2
HOVERGENQ5TEJ8
HOGENOMQ5TEJ8
Homologs : HomoloGeneTHEMIS2
Homology/Alignments : Family Browser (UCSC)THEMIS2
Gene fusions - Rearrangements
Tumor Fusion PortalTHEMIS2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTHEMIS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)THEMIS2
dbVarTHEMIS2
ClinVarTHEMIS2
1000_GenomesTHEMIS2 
Exome Variant ServerTHEMIS2
ExAC (Exome Aggregation Consortium)ENSG00000130775
GNOMAD BrowserENSG00000130775
Genetic variants : HAPMAP9473
Genomic Variants (DGV)THEMIS2 [DGVbeta]
DECIPHERTHEMIS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTHEMIS2 
Mutations
ICGC Data PortalTHEMIS2 
TCGA Data PortalTHEMIS2 
Broad Tumor PortalTHEMIS2
OASIS PortalTHEMIS2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDTHEMIS2
BioMutasearch THEMIS2
DgiDB (Drug Gene Interaction Database)THEMIS2
DoCM (Curated mutations)THEMIS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)THEMIS2 (select a term)
intoGenTHEMIS2
Cancer3DTHEMIS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTHEMIS2
MedgenTHEMIS2
Genetic Testing Registry THEMIS2
NextProtQ5TEJ8 [Medical]
TSGene9473
GENETestsTHEMIS2
Target ValidationTHEMIS2
Huge Navigator THEMIS2 [HugePedia]
snp3D : Map Gene to Disease9473
BioCentury BCIQTHEMIS2
ClinGenTHEMIS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9473
Chemical/Pharm GKB GenePA128394550
Clinical trialTHEMIS2
Miscellaneous
canSAR (ICR)THEMIS2 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTHEMIS2
EVEXTHEMIS2
GoPubMedTHEMIS2
iHOPTHEMIS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:38:23 CET 2017

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