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THG1L (tRNA-histidine guanylyltransferase 1 like)

Identity

Alias_namestRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
tRNA-histidine guanylyltransferase 1-like
Alias_symbol (synonym)ICF45
FLJ11601
FLJ20546
IHG-1
hTHG1
Other alias
HGNC (Hugo) THG1L
LocusID (NCBI) 54974
Atlas_Id 56058
Location 5q33.3  [Link to chromosome band 5q33]
Location_base_pair Starts at 157731389 and ends at 157741447 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
THG1L (5q33.3) / PLEKHA1 (10q26.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)THG1L   26053
Cards
Entrez_Gene (NCBI)THG1L  54974  tRNA-histidine guanylyltransferase 1 like
AliasesICF45; IHG-1; hTHG1
GeneCards (Weizmann)THG1L
Ensembl hg19 (Hinxton)ENSG00000113272 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113272 [Gene_View]  chr5:157731389-157741447 [Contig_View]  THG1L [Vega]
ICGC DataPortalENSG00000113272
TCGA cBioPortalTHG1L
AceView (NCBI)THG1L
Genatlas (Paris)THG1L
WikiGenes54974
SOURCE (Princeton)THG1L
Genetics Home Reference (NIH)THG1L
Genomic and cartography
GoldenPath hg38 (UCSC)THG1L  -     chr5:157731389-157741447 +  5q33.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)THG1L  -     5q33.3   [Description]    (hg19-Feb_2009)
EnsemblTHG1L - 5q33.3 [CytoView hg19]  THG1L - 5q33.3 [CytoView hg38]
Mapping of homologs : NCBITHG1L [Mapview hg19]  THG1L [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF086486 AK000553 AK021663 AK023355 AK223119
RefSeq transcript (Entrez)NM_001317824 NM_001317825 NM_001317826 NM_017872
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)THG1L
Cluster EST : UnigeneHs.734786 [ NCBI ]
CGAP (NCI)Hs.734786
Alternative Splicing GalleryENSG00000113272
Gene ExpressionTHG1L [ NCBI-GEO ]   THG1L [ EBI - ARRAY_EXPRESS ]   THG1L [ SEEK ]   THG1L [ MEM ]
Gene Expression Viewer (FireBrowse)THG1L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54974
GTEX Portal (Tissue expression)THG1L
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NWX6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NWX6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NWX6
Splice isoforms : SwissVarQ9NWX6
Catalytic activity : Enzyme2.7.7.79 [ Enzyme-Expasy ]   2.7.7.792.7.7.79 [ IntEnz-EBI ]   2.7.7.79 [ BRENDA ]   2.7.7.79 [ KEGG ]   
PhosPhoSitePlusQ9NWX6
Domains : Interpro (EBI)Thg1_C_dom    tRNAHis_GuaTrfase_cat    tRNAHis_GuaTrfase_Thg1   
Domain families : Pfam (Sanger)Thg1 (PF04446)    Thg1C (PF14413)   
Domain families : Pfam (NCBI)pfam04446    pfam14413   
Conserved Domain (NCBI)THG1L
DMDM Disease mutations54974
Blocks (Seattle)THG1L
PDB (SRS)3OTB    3OTC    3OTD    3OTE   
PDB (PDBSum)3OTB    3OTC    3OTD    3OTE   
PDB (IMB)3OTB    3OTC    3OTD    3OTE   
PDB (RSDB)3OTB    3OTC    3OTD    3OTE   
Structural Biology KnowledgeBase3OTB    3OTC    3OTD    3OTE   
SCOP (Structural Classification of Proteins)3OTB    3OTC    3OTD    3OTE   
CATH (Classification of proteins structures)3OTB    3OTC    3OTD    3OTE   
SuperfamilyQ9NWX6
Human Protein AtlasENSG00000113272
Peptide AtlasQ9NWX6
HPRD13726
IPIIPI00016559   IPI00908961   IPI01013258   IPI00985325   IPI00982140   
Protein Interaction databases
DIP (DOE-UCLA)Q9NWX6
IntAct (EBI)Q9NWX6
FunCoupENSG00000113272
BioGRIDTHG1L
STRING (EMBL)THG1L
ZODIACTHG1L
Ontologies - Pathways
QuickGOQ9NWX6
Ontology : AmiGOtRNA binding  magnesium ion binding  protein binding  ATP binding  GTP binding  mitochondrion  cytosol  tRNA modification  tRNA modification  tRNA processing  tRNA guanylyltransferase activity  tRNA guanylyltransferase activity  nucleotidyltransferase activity  identical protein binding  protein homotetramerization  protein homotetramerization  
Ontology : EGO-EBItRNA binding  magnesium ion binding  protein binding  ATP binding  GTP binding  mitochondrion  cytosol  tRNA modification  tRNA modification  tRNA processing  tRNA guanylyltransferase activity  tRNA guanylyltransferase activity  nucleotidyltransferase activity  identical protein binding  protein homotetramerization  protein homotetramerization  
NDEx NetworkTHG1L
Atlas of Cancer Signalling NetworkTHG1L
Wikipedia pathwaysTHG1L
Orthology - Evolution
OrthoDB54974
GeneTree (enSembl)ENSG00000113272
Phylogenetic Trees/Animal Genes : TreeFamTHG1L
HOVERGENQ9NWX6
HOGENOMQ9NWX6
Homologs : HomoloGeneTHG1L
Homology/Alignments : Family Browser (UCSC)THG1L
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTHG1L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)THG1L
dbVarTHG1L
ClinVarTHG1L
1000_GenomesTHG1L 
Exome Variant ServerTHG1L
ExAC (Exome Aggregation Consortium)THG1L (select the gene name)
Genetic variants : HAPMAP54974
Genomic Variants (DGV)THG1L [DGVbeta]
DECIPHERTHG1L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTHG1L 
Mutations
ICGC Data PortalTHG1L 
TCGA Data PortalTHG1L 
Broad Tumor PortalTHG1L
OASIS PortalTHG1L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTHG1L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTHG1L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch THG1L
DgiDB (Drug Gene Interaction Database)THG1L
DoCM (Curated mutations)THG1L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)THG1L (select a term)
intoGenTHG1L
Cancer3DTHG1L(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTHG1L
Genetic Testing Registry THG1L
NextProtQ9NWX6 [Medical]
TSGene54974
GENETestsTHG1L
Target ValidationTHG1L
Huge Navigator THG1L [HugePedia]
snp3D : Map Gene to Disease54974
BioCentury BCIQTHG1L
ClinGenTHG1L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54974
Chemical/Pharm GKB GenePA162405691
Clinical trialTHG1L
Miscellaneous
canSAR (ICR)THG1L (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTHG1L
EVEXTHG1L
GoPubMedTHG1L
iHOPTHG1L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:16:51 CEST 2017

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