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THNSL1 (threonine synthase-like 1 (S. cerevisiae))

Identity

Alias_namesthreonine synthase-like 1 (bacterial)
threonine synthase-like 1 (S. cerevisiae)
threonine synthase-like 1
Alias_symbol (synonym)FLJ22002
TSH1
Other alias
HGNC (Hugo) THNSL1
LocusID (NCBI) 79896
Atlas_Id 74677
Location 10p12.1  [Link to chromosome band 10p12]
Location_base_pair Starts at 25305508 and ends at 25315593 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)THNSL1   26160
Cards
Entrez_Gene (NCBI)THNSL1  79896  threonine synthase-like 1 (S. cerevisiae)
AliasesTSH1
GeneCards (Weizmann)THNSL1
Ensembl hg19 (Hinxton)ENSG00000185875 [Gene_View]  chr10:25305508-25315593 [Contig_View]  THNSL1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000185875 [Gene_View]  chr10:25305508-25315593 [Contig_View]  THNSL1 [Vega]
ICGC DataPortalENSG00000185875
TCGA cBioPortalTHNSL1
AceView (NCBI)THNSL1
Genatlas (Paris)THNSL1
WikiGenes79896
SOURCE (Princeton)THNSL1
Genetics Home Reference (NIH)THNSL1
Genomic and cartography
GoldenPath hg19 (UCSC)THNSL1  -     chr10:25305508-25315593 +  10p12.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)THNSL1  -     10p12.1   [Description]    (hg38-Dec_2013)
EnsemblTHNSL1 - 10p12.1 [CytoView hg19]  THNSL1 - 10p12.1 [CytoView hg38]
Mapping of homologs : NCBITHNSL1 [Mapview hg19]  THNSL1 [Mapview hg38]
OMIM611260   
Gene and transcription
Genbank (Entrez)AK025655 AK094362 AK125249 BC016697 BC035132
RefSeq transcript (Entrez)NM_024838
RefSeq genomic (Entrez)NC_000010 NC_018921 NT_008705 NW_004929370
Consensus coding sequences : CCDS (NCBI)THNSL1
Cluster EST : UnigeneHs.645274 [ NCBI ]
CGAP (NCI)Hs.645274
Alternative Splicing GalleryENSG00000185875
Gene ExpressionTHNSL1 [ NCBI-GEO ]   THNSL1 [ EBI - ARRAY_EXPRESS ]   THNSL1 [ SEEK ]   THNSL1 [ MEM ]
Gene Expression Viewer (FireBrowse)THNSL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79896
GTEX Portal (Tissue expression)THNSL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IYQ7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IYQ7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IYQ7
Splice isoforms : SwissVarQ8IYQ7
PhosPhoSitePlusQ8IYQ7
Domains : Interpro (EBI)P-loop_NTPase    Shikimate_kinase/TSH1    Thr_synth_N    Thr_synthase_like    TrpB-like_PLP-dep   
Domain families : Pfam (Sanger)PALP (PF00291)    SKI (PF01202)    Thr_synth_N (PF14821)   
Domain families : Pfam (NCBI)pfam00291    pfam01202    pfam14821   
Conserved Domain (NCBI)THNSL1
DMDM Disease mutations79896
Blocks (Seattle)THNSL1
SuperfamilyQ8IYQ7
Human Protein AtlasENSG00000185875
Peptide AtlasQ8IYQ7
HPRD07974
IPIIPI00016287   
Protein Interaction databases
DIP (DOE-UCLA)Q8IYQ7
IntAct (EBI)Q8IYQ7
FunCoupENSG00000185875
BioGRIDTHNSL1
STRING (EMBL)THNSL1
ZODIACTHNSL1
Ontologies - Pathways
QuickGOQ8IYQ7
Ontology : AmiGOmolecular_function  threonine synthase activity  cellular_component  nucleus  nucleoplasm  cytoplasm  mitochondrion  biological_process  threonine biosynthetic process  pyridoxal phosphate binding  
Ontology : EGO-EBImolecular_function  threonine synthase activity  cellular_component  nucleus  nucleoplasm  cytoplasm  mitochondrion  biological_process  threonine biosynthetic process  pyridoxal phosphate binding  
NDEx NetworkTHNSL1
Atlas of Cancer Signalling NetworkTHNSL1
Wikipedia pathwaysTHNSL1
Orthology - Evolution
OrthoDB79896
GeneTree (enSembl)ENSG00000185875
Phylogenetic Trees/Animal Genes : TreeFamTHNSL1
HOVERGENQ8IYQ7
HOGENOMQ8IYQ7
Homologs : HomoloGeneTHNSL1
Homology/Alignments : Family Browser (UCSC)THNSL1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTHNSL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)THNSL1
dbVarTHNSL1
ClinVarTHNSL1
1000_GenomesTHNSL1 
Exome Variant ServerTHNSL1
ExAC (Exome Aggregation Consortium)THNSL1 (select the gene name)
Genetic variants : HAPMAP79896
Genomic Variants (DGV)THNSL1 [DGVbeta]
DECIPHER (Syndromes)10:25305508-25315593  ENSG00000185875
CONAN: Copy Number AnalysisTHNSL1 
Mutations
ICGC Data PortalTHNSL1 
TCGA Data PortalTHNSL1 
Broad Tumor PortalTHNSL1
OASIS PortalTHNSL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTHNSL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTHNSL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch THNSL1
DgiDB (Drug Gene Interaction Database)THNSL1
DoCM (Curated mutations)THNSL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)THNSL1 (select a term)
intoGenTHNSL1
Cancer3DTHNSL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611260   
Orphanet
MedgenTHNSL1
Genetic Testing Registry THNSL1
NextProtQ8IYQ7 [Medical]
TSGene79896
GENETestsTHNSL1
Huge Navigator THNSL1 [HugePedia]
snp3D : Map Gene to Disease79896
BioCentury BCIQTHNSL1
ClinGenTHNSL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79896
Chemical/Pharm GKB GenePA134906927
Clinical trialTHNSL1
Miscellaneous
canSAR (ICR)THNSL1 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTHNSL1
EVEXTHNSL1
GoPubMedTHNSL1
iHOPTHNSL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:48:02 CET 2017

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