Atlas of Genetics and Cytogenetics in Oncology and Haematology


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THOC6 (THO complex 6)

Identity

Alias_namesWDR58
WD repeat domain 58
THO complex 6 homolog (Drosophila)
Alias_symbol (synonym)MGC2655
fSAP35
Other aliasBBIS
HGNC (Hugo) THOC6
LocusID (NCBI) 79228
Atlas_Id 74681
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 3074032 and ends at 3077756 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
THOC6 (16p13.3) / PCBP2 (12q13.13)THOC6 (16p13.3) / THOC6 (16p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)THOC6   28369
Cards
Entrez_Gene (NCBI)THOC6  79228  THO complex 6
AliasesBBIS; WDR58; fSAP35
GeneCards (Weizmann)THOC6
Ensembl hg19 (Hinxton)ENSG00000131652 [Gene_View]  chr16:3074032-3077756 [Contig_View]  THOC6 [Vega]
Ensembl hg38 (Hinxton)ENSG00000131652 [Gene_View]  chr16:3074032-3077756 [Contig_View]  THOC6 [Vega]
ICGC DataPortalENSG00000131652
TCGA cBioPortalTHOC6
AceView (NCBI)THOC6
Genatlas (Paris)THOC6
WikiGenes79228
SOURCE (Princeton)THOC6
Genetics Home Reference (NIH)THOC6
Genomic and cartography
GoldenPath hg19 (UCSC)THOC6  -     chr16:3074032-3077756 +  16p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)THOC6  -     16p13.3   [Description]    (hg38-Dec_2013)
EnsemblTHOC6 - 16p13.3 [CytoView hg19]  THOC6 - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBITHOC6 [Mapview hg19]  THOC6 [Mapview hg38]
OMIM613680   615403   
Gene and transcription
Genbank (Entrez)AK075330 AK308960 AK310113 AK314086 AL832548
RefSeq transcript (Entrez)NM_001142350 NM_024339
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010393 NW_004929400
Consensus coding sequences : CCDS (NCBI)THOC6
Cluster EST : UnigeneHs.412304 [ NCBI ]
CGAP (NCI)Hs.412304
Alternative Splicing GalleryENSG00000131652
Gene ExpressionTHOC6 [ NCBI-GEO ]   THOC6 [ EBI - ARRAY_EXPRESS ]   THOC6 [ SEEK ]   THOC6 [ MEM ]
Gene Expression Viewer (FireBrowse)THOC6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79228
GTEX Portal (Tissue expression)THOC6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86W42   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86W42  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86W42
Splice isoforms : SwissVarQ86W42
PhosPhoSitePlusQ86W42
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)THOC6
DMDM Disease mutations79228
Blocks (Seattle)THOC6
SuperfamilyQ86W42
Human Protein AtlasENSG00000131652
Peptide AtlasQ86W42
HPRD14504
IPIIPI00328985   IPI00641826   IPI00301252   
Protein Interaction databases
DIP (DOE-UCLA)Q86W42
IntAct (EBI)Q86W42
FunCoupENSG00000131652
BioGRIDTHOC6
STRING (EMBL)THOC6
ZODIACTHOC6
Ontologies - Pathways
QuickGOQ86W42
Ontology : AmiGOtranscription export complex  THO complex  THO complex part of transcription export complex  RNA binding  nucleus  nucleoplasm  mRNA processing  mRNA export from nucleus  apoptotic process  central nervous system development  RNA splicing  nuclear speck  negative regulation of apoptotic process  viral mRNA export from host cell nucleus  
Ontology : EGO-EBItranscription export complex  THO complex  THO complex part of transcription export complex  RNA binding  nucleus  nucleoplasm  mRNA processing  mRNA export from nucleus  apoptotic process  central nervous system development  RNA splicing  nuclear speck  negative regulation of apoptotic process  viral mRNA export from host cell nucleus  
Pathways : KEGGRNA transport   
NDEx NetworkTHOC6
Atlas of Cancer Signalling NetworkTHOC6
Wikipedia pathwaysTHOC6
Orthology - Evolution
OrthoDB79228
GeneTree (enSembl)ENSG00000131652
Phylogenetic Trees/Animal Genes : TreeFamTHOC6
HOVERGENQ86W42
HOGENOMQ86W42
Homologs : HomoloGeneTHOC6
Homology/Alignments : Family Browser (UCSC)THOC6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTHOC6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)THOC6
dbVarTHOC6
ClinVarTHOC6
1000_GenomesTHOC6 
Exome Variant ServerTHOC6
ExAC (Exome Aggregation Consortium)THOC6 (select the gene name)
Genetic variants : HAPMAP79228
Genomic Variants (DGV)THOC6 [DGVbeta]
DECIPHER (Syndromes)16:3074032-3077756  ENSG00000131652
CONAN: Copy Number AnalysisTHOC6 
Mutations
ICGC Data PortalTHOC6 
TCGA Data PortalTHOC6 
Broad Tumor PortalTHOC6
OASIS PortalTHOC6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTHOC6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTHOC6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch THOC6
DgiDB (Drug Gene Interaction Database)THOC6
DoCM (Curated mutations)THOC6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)THOC6 (select a term)
intoGenTHOC6
Cancer3DTHOC6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613680    615403   
Orphanet22305   
MedgenTHOC6
Genetic Testing Registry THOC6
NextProtQ86W42 [Medical]
TSGene79228
GENETestsTHOC6
Huge Navigator THOC6 [HugePedia]
snp3D : Map Gene to Disease79228
BioCentury BCIQTHOC6
ClinGenTHOC6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79228
Chemical/Pharm GKB GenePA142670592
Clinical trialTHOC6
Miscellaneous
canSAR (ICR)THOC6 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTHOC6
EVEXTHOC6
GoPubMedTHOC6
iHOPTHOC6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:48:03 CET 2017

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