THSD7A (thrombospondin type 1 domain containing 7A)

2017-08-01  

Identity

HGNC
LOCATION
7p21.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 221981
MIM: 612249
HGNC: 22207
Ensembl: ENSG00000005108

Variants:

dbSNP: 221981
ClinVar: 221981
TCGA: ENSG00000005108
COSMIC: THSD7A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000005108ENST00000423059Q9UPZ6
ENSG00000005108ENST00000617773A0A087WY08

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
O-linked glycosylationREACTOMER-HSA-5173105
O-glycosylation of TSR domain-containing proteinsREACTOMER-HSA-5173214
DiseaseREACTOMER-HSA-1643685
Diseases of glycosylationREACTOMER-HSA-3781865
Diseases associated with O-glycosylation of proteinsREACTOMER-HSA-3906995
Defective B3GALTL causes Peters-plus syndrome (PpS)REACTOMER-HSA-5083635

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
253943212014Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy.158
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
200204852010Thrombospondin type I domain containing 7A (THSD7A) mediates endothelial cell migration and tube formation.24
263933522015Prevalence of Enhanced Granular Expression of Thrombospondin Type-1 Domain-Containing 7A in the Glomeruli of Japanese Patients with Idiopathic Membranous Nephropathy.24
221949722011Soluble THSD7A is an N-glycoprotein that promotes endothelial cell migration and tube formation in angiogenesis.23
267961332016Hypoxia-inducible miR-210 contributes to preeclampsia via targeting thrombospondin type I domain containing 7A.20
288015272017Circulating Antibodies against Thrombospondin Type-I Domain-Containing 7A in Chinese Patients with Idiopathic Membranous Nephropathy.13
208088252010Novel association strategy with copy number variation for identifying new risk Loci of human diseases.11
276349092016Biomarkers to detect membranous nephropathy in Chinese patients.9
280357182017THSD7A expression in human cancer.8

Citation

Dessen P

THSD7A (thrombospondin type 1 domain containing 7A)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/56989/thsd7a