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TIMM22 (translocase of inner mitochondrial membrane 22)

Identity

Alias (NCBI)COXPD43
TEX4
TIM22
HGNC (Hugo) TIMM22
HGNC Alias symbTIM22
HGNC Previous nameTEX4
HGNC Previous nametestis-expressed sequence 4
 translocase of inner mitochondrial membrane 22 homolog (yeast)
LocusID (NCBI) 29928
Atlas_Id 74705
Location 17p13.3  [Link to chromosome band 17p13]
Location_base_pair Starts at 997129 and ends at 1003671 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TIMM22   17317
Cards
Entrez_Gene (NCBI)TIMM22    translocase of inner mitochondrial membrane 22
AliasesCOXPD43; TEX4; TIM22
GeneCards (Weizmann)TIMM22
Ensembl hg19 (Hinxton)ENSG00000177370 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000177370 [Gene_View]  ENSG00000177370 [Sequence]  chr17:997129-1003671 [Contig_View]  TIMM22 [Vega]
ICGC DataPortalENSG00000177370
TCGA cBioPortalTIMM22
AceView (NCBI)TIMM22
Genatlas (Paris)TIMM22
SOURCE (Princeton)TIMM22
Genetics Home Reference (NIH)TIMM22
Genomic and cartography
GoldenPath hg38 (UCSC)TIMM22  -     chr17:997129-1003671 +  17p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TIMM22  -     17p13.3   [Description]    (hg19-Feb_2009)
GoldenPathTIMM22 - 17p13.3 [CytoView hg19]  TIMM22 - 17p13.3 [CytoView hg38]
ImmunoBaseENSG00000177370
Genome Data Viewer NCBITIMM22 [Mapview hg19]  
OMIM607251   618851   
Gene and transcription
Genbank (Entrez)AF155330 AI522232 AK000830 AK225453 BC002324
RefSeq transcript (Entrez)NM_013337
Consensus coding sequences : CCDS (NCBI)TIMM22
Gene ExpressionTIMM22 [ NCBI-GEO ]   TIMM22 [ EBI - ARRAY_EXPRESS ]   TIMM22 [ SEEK ]   TIMM22 [ MEM ]
Gene Expression Viewer (FireBrowse)TIMM22 [ Firebrowse - Broad ]
GenevisibleExpression of TIMM22 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29928
GTEX Portal (Tissue expression)TIMM22
Human Protein AtlasENSG00000177370-TIMM22 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y584   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y584  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y584
PhosPhoSitePlusQ9Y584
Domains : Interpro (EBI)TIM22   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TIMM22
PDB (RSDB)7CGP   
PDB Europe7CGP   
PDB (PDBSum)7CGP   
PDB (IMB)7CGP   
Structural Biology KnowledgeBase7CGP   
SCOP (Structural Classification of Proteins)7CGP   
CATH (Classification of proteins structures)7CGP   
SuperfamilyQ9Y584
AlphaFold pdb e-kbQ9Y584   
Human Protein Atlas [tissue]ENSG00000177370-TIMM22 [tissue]
HPRD06262
Protein Interaction databases
DIP (DOE-UCLA)Q9Y584
IntAct (EBI)Q9Y584
BioGRIDTIMM22
STRING (EMBL)TIMM22
ZODIACTIMM22
Ontologies - Pathways
QuickGOQ9Y584
Ontology : AmiGOprotein binding  mitochondrial inner membrane  protein targeting to mitochondrion  protein transmembrane transporter activity  protein transmembrane transporter activity  integral component of membrane  mitochondrion targeting sequence binding  TIM22 mitochondrial import inner membrane insertion complex  TIM22 mitochondrial import inner membrane insertion complex  protein insertion into mitochondrial inner membrane  protein insertion into mitochondrial inner membrane  protein insertion into mitochondrial inner membrane  protein insertion into mitochondrial inner membrane  protein transmembrane transport  protein transporter activity  
Ontology : EGO-EBIprotein binding  mitochondrial inner membrane  protein targeting to mitochondrion  protein transmembrane transporter activity  protein transmembrane transporter activity  integral component of membrane  mitochondrion targeting sequence binding  TIM22 mitochondrial import inner membrane insertion complex  TIM22 mitochondrial import inner membrane insertion complex  protein insertion into mitochondrial inner membrane  protein insertion into mitochondrial inner membrane  protein insertion into mitochondrial inner membrane  protein insertion into mitochondrial inner membrane  protein transmembrane transport  protein transporter activity  
NDEx NetworkTIMM22
Atlas of Cancer Signalling NetworkTIMM22
Wikipedia pathwaysTIMM22
Orthology - Evolution
OrthoDB29928
GeneTree (enSembl)ENSG00000177370
Phylogenetic Trees/Animal Genes : TreeFamTIMM22
Homologs : HomoloGeneTIMM22
Homology/Alignments : Family Browser (UCSC)TIMM22
Gene fusions - Rearrangements
Fusion : QuiverTIMM22
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTIMM22 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TIMM22
dbVarTIMM22
ClinVarTIMM22
MonarchTIMM22
1000_GenomesTIMM22 
Exome Variant ServerTIMM22
GNOMAD BrowserENSG00000177370
Varsome BrowserTIMM22
ACMGTIMM22 variants
VarityQ9Y584
Genomic Variants (DGV)TIMM22 [DGVbeta]
DECIPHERTIMM22 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTIMM22 
Mutations
ICGC Data PortalTIMM22 
TCGA Data PortalTIMM22 
Broad Tumor PortalTIMM22
OASIS PortalTIMM22 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTIMM22  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTIMM22
Mutations and Diseases : HGMDTIMM22
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTIMM22
DgiDB (Drug Gene Interaction Database)TIMM22
DoCM (Curated mutations)TIMM22
CIViC (Clinical Interpretations of Variants in Cancer)TIMM22
Cancer3DTIMM22
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607251    618851   
Orphanet
DisGeNETTIMM22
MedgenTIMM22
Genetic Testing Registry TIMM22
NextProtQ9Y584 [Medical]
GENETestsTIMM22
Target ValidationTIMM22
Huge Navigator TIMM22 [HugePedia]
ClinGenTIMM22
Clinical trials, drugs, therapy
MyCancerGenomeTIMM22
Protein Interactions : CTDTIMM22
Pharm GKB GenePA38230
PharosQ9Y584
Clinical trialTIMM22
Miscellaneous
canSAR (ICR)TIMM22
HarmonizomeTIMM22
DataMed IndexTIMM22
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTIMM22
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 16:25:33 CEST 2021

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