Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TIMM50 (translocase of inner mitochondrial membrane 50)

Identity

Alias (NCBI)MGCA9
TIM50
TIM50L
HGNC (Hugo) TIMM50
HGNC Alias symbTIM50L
TIM50
HGNC Previous nametranslocase of inner mitochondrial membrane 50 homolog (yeast)
LocusID (NCBI) 92609
Atlas_Id 52410
Location 19q13.2  [Link to chromosome band 19q13]
Location_base_pair Starts at 39480838 and ends at 39493779 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AGRN (1p36.33) / TIMM50 (19q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TIMM50   23656
Cards
Entrez_Gene (NCBI)TIMM50    translocase of inner mitochondrial membrane 50
AliasesMGCA9; TIM50; TIM50L
GeneCards (Weizmann)TIMM50
Ensembl hg19 (Hinxton)ENSG00000105197 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105197 [Gene_View]  ENSG00000105197 [Sequence]  chr19:39480838-39493779 [Contig_View]  TIMM50 [Vega]
ICGC DataPortalENSG00000105197
TCGA cBioPortalTIMM50
AceView (NCBI)TIMM50
Genatlas (Paris)TIMM50
SOURCE (Princeton)TIMM50
Genetics Home Reference (NIH)TIMM50
Genomic and cartography
GoldenPath hg38 (UCSC)TIMM50  -     chr19:39480838-39493779 +  19q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TIMM50  -     19q13.2   [Description]    (hg19-Feb_2009)
GoldenPathTIMM50 - 19q13.2 [CytoView hg19]  TIMM50 - 19q13.2 [CytoView hg38]
ImmunoBaseENSG00000105197
Genome Data Viewer NCBITIMM50 [Mapview hg19]  
OMIM607381   617698   
Gene and transcription
Genbank (Entrez)AI762706 AK092396 AK097291 AK098197 AY444561
RefSeq transcript (Entrez)NM_001001563 NM_001329559
Consensus coding sequences : CCDS (NCBI)TIMM50
Gene ExpressionTIMM50 [ NCBI-GEO ]   TIMM50 [ EBI - ARRAY_EXPRESS ]   TIMM50 [ SEEK ]   TIMM50 [ MEM ]
Gene Expression Viewer (FireBrowse)TIMM50 [ Firebrowse - Broad ]
GenevisibleExpression of TIMM50 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)92609
GTEX Portal (Tissue expression)TIMM50
Human Protein AtlasENSG00000105197-TIMM50 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ3ZCQ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ3ZCQ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ3ZCQ8
PhosPhoSitePlusQ3ZCQ8
Domaine pattern : Prosite (Expaxy)FCP1 (PS50969)   
Domains : Interpro (EBI)FCP1_dom    HAD-like_sf    HAD_sf    Tim50   
Domain families : Pfam (Sanger)NIF (PF03031)   
Domain families : Pfam (NCBI)pfam03031   
Domain families : Smart (EMBL)CPDc (SM00577)  
Conserved Domain (NCBI)TIMM50
SuperfamilyQ3ZCQ8
AlphaFold pdb e-kbQ3ZCQ8   
Human Protein Atlas [tissue]ENSG00000105197-TIMM50 [tissue]
HPRD12118
Protein Interaction databases
DIP (DOE-UCLA)Q3ZCQ8
IntAct (EBI)Q3ZCQ8
BioGRIDTIMM50
STRING (EMBL)TIMM50
ZODIACTIMM50
Ontologies - Pathways
QuickGOQ3ZCQ8
Ontology : AmiGOrelease of cytochrome c from mitochondria  RNA binding  phosphoprotein phosphatase activity  phosphoprotein phosphatase activity  protein serine/threonine phosphatase activity  protein tyrosine phosphatase activity  interleukin-2 receptor binding  protein binding  nucleoplasm  mitochondrion  mitochondrial inner membrane  TIM23 mitochondrial import inner membrane translocase complex  TIM23 mitochondrial import inner membrane translocase complex  protein dephosphorylation  mitochondrial membrane organization  integral component of membrane  nuclear speck  protein import into mitochondrial matrix  peptidyl-tyrosine dephosphorylation  ribonucleoprotein complex binding  
Ontology : EGO-EBIrelease of cytochrome c from mitochondria  RNA binding  phosphoprotein phosphatase activity  phosphoprotein phosphatase activity  protein serine/threonine phosphatase activity  protein tyrosine phosphatase activity  interleukin-2 receptor binding  protein binding  nucleoplasm  mitochondrion  mitochondrial inner membrane  TIM23 mitochondrial import inner membrane translocase complex  TIM23 mitochondrial import inner membrane translocase complex  protein dephosphorylation  mitochondrial membrane organization  integral component of membrane  nuclear speck  protein import into mitochondrial matrix  peptidyl-tyrosine dephosphorylation  ribonucleoprotein complex binding  
NDEx NetworkTIMM50
Atlas of Cancer Signalling NetworkTIMM50
Wikipedia pathwaysTIMM50
Orthology - Evolution
OrthoDB92609
GeneTree (enSembl)ENSG00000105197
Phylogenetic Trees/Animal Genes : TreeFamTIMM50
Homologs : HomoloGeneTIMM50
Homology/Alignments : Family Browser (UCSC)TIMM50
Gene fusions - Rearrangements
Fusion : QuiverTIMM50
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTIMM50 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TIMM50
dbVarTIMM50
ClinVarTIMM50
MonarchTIMM50
1000_GenomesTIMM50 
Exome Variant ServerTIMM50
GNOMAD BrowserENSG00000105197
Varsome BrowserTIMM50
ACMGTIMM50 variants
VarityQ3ZCQ8
Genomic Variants (DGV)TIMM50 [DGVbeta]
DECIPHERTIMM50 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTIMM50 
Mutations
ICGC Data PortalTIMM50 
TCGA Data PortalTIMM50 
Broad Tumor PortalTIMM50
OASIS PortalTIMM50 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTIMM50  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTIMM50
Mutations and Diseases : HGMDTIMM50
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTIMM50
DgiDB (Drug Gene Interaction Database)TIMM50
DoCM (Curated mutations)TIMM50
CIViC (Clinical Interpretations of Variants in Cancer)TIMM50
Cancer3DTIMM50
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607381    617698   
Orphanet
DisGeNETTIMM50
MedgenTIMM50
Genetic Testing Registry TIMM50
NextProtQ3ZCQ8 [Medical]
GENETestsTIMM50
Target ValidationTIMM50
Huge Navigator TIMM50 [HugePedia]
ClinGenTIMM50
Clinical trials, drugs, therapy
MyCancerGenomeTIMM50
Protein Interactions : CTDTIMM50
Pharm GKB GenePA134902846
PharosQ3ZCQ8
Clinical trialTIMM50
Miscellaneous
canSAR (ICR)TIMM50
HarmonizomeTIMM50
DataMed IndexTIMM50
Probes
Litterature
PubMed124 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTIMM50
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:35:07 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.