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TINF2 (TERF1 (TRF1)-interacting nuclear factor 2)

Identity

Other namesDKCA3
TIN2
HGNC (Hugo) TINF2
LocusID (NCBI) 26277
Atlas_Id 42575
Location 14q12
Location_base_pair Starts at 24708851 and ends at 24711880 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TINF2   11824
Cards
Entrez_Gene (NCBI)TINF2  26277  TERF1 (TRF1)-interacting nuclear factor 2
GeneCards (Weizmann)TINF2
Ensembl hg19 (Hinxton)ENSG00000092330 [Gene_View]  chr14:24708851-24711880 [Contig_View]  TINF2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000092330 [Gene_View]  chr14:24708851-24711880 [Contig_View]  TINF2 [Vega]
ICGC DataPortalENSG00000092330
TCGA cBioPortalTINF2
AceView (NCBI)TINF2
Genatlas (Paris)TINF2
WikiGenes26277
SOURCE (Princeton)TINF2
Genomic and cartography
GoldenPath hg19 (UCSC)TINF2  -     chr14:24708851-24711880 -  14q12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TINF2  -     14q12   [Description]    (hg38-Dec_2013)
EnsemblTINF2 - 14q12 [CytoView hg19]  TINF2 - 14q12 [CytoView hg38]
Mapping of homologs : NCBITINF2 [Mapview hg19]  TINF2 [Mapview hg38]
OMIM127550   268130   604319   613990   
Gene and transcription
Genbank (Entrez)AF195512 AK023166 AK225379 AK294119 AK315084
RefSeq transcript (Entrez)NM_001099274 NM_012461
RefSeq genomic (Entrez)NC_000014 NC_018925 NG_016650 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)TINF2
Cluster EST : UnigeneHs.496191 [ NCBI ]
CGAP (NCI)Hs.496191
Alternative Splicing : Fast-db (Paris)GSHG0009263
Alternative Splicing GalleryENSG00000092330
Gene ExpressionTINF2 [ NCBI-GEO ]     TINF2 [ SEEK ]   TINF2 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BSI4 (Uniprot)
NextProtQ9BSI4  [Medical]  [Publications]
With graphics : InterProQ9BSI4
Splice isoforms : SwissVarQ9BSI4 (Swissvar)
Domains : Interpro (EBI)TINF2_N   
Related proteins : CluSTrQ9BSI4
Domain families : Pfam (Sanger)TINF2_N (PF14973)   
Domain families : Pfam (NCBI)pfam14973   
DMDM Disease mutations26277
Blocks (Seattle)Q9BSI4
PDB (SRS)3BQO    3BU8   
PDB (PDBSum)3BQO    3BU8   
PDB (IMB)3BQO    3BU8   
PDB (RSDB)3BQO    3BU8   
Human Protein AtlasENSG00000092330
Peptide AtlasQ9BSI4
HPRD16056
IPIIPI00074109   IPI00218680   IPI00218681   IPI01010915   IPI01011406   
Protein Interaction databases
DIP (DOE-UCLA)Q9BSI4
IntAct (EBI)Q9BSI4
FunCoupENSG00000092330
BioGRIDTINF2
IntegromeDBTINF2
STRING (EMBL)TINF2
Ontologies - Pathways
QuickGOQ9BSI4
Ontology : AmiGOtelomere maintenance  chromosome, telomeric region  nuclear telomere cap complex  DNA binding  protein binding  nucleus  nucleoplasm  perinucleolar chromocenter  telomere maintenance via telomere lengthening  negative regulation of protein ADP-ribosylation  nuclear matrix  telomere assembly  positive regulation of telomere maintenance  negative regulation of telomere maintenance via telomerase  negative regulation of telomere maintenance via telomerase  protein localization to chromosome  telomeric DNA binding  negative regulation of epithelial cell proliferation  protein localization to chromosome, telomeric region  
Ontology : EGO-EBItelomere maintenance  chromosome, telomeric region  nuclear telomere cap complex  DNA binding  protein binding  nucleus  nucleoplasm  perinucleolar chromocenter  telomere maintenance via telomere lengthening  negative regulation of protein ADP-ribosylation  nuclear matrix  telomere assembly  positive regulation of telomere maintenance  negative regulation of telomere maintenance via telomerase  negative regulation of telomere maintenance via telomerase  protein localization to chromosome  telomeric DNA binding  negative regulation of epithelial cell proliferation  protein localization to chromosome, telomeric region  
Protein Interaction DatabaseTINF2
DoCM (Curated mutations)TINF2
Wikipedia pathwaysTINF2
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerTINF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TINF2
dbVarTINF2
ClinVarTINF2
1000_GenomesTINF2 
Exome Variant ServerTINF2
SNP (GeneSNP Utah)TINF2
SNP : HGBaseTINF2
Genetic variants : HAPMAPTINF2
Genomic Variants (DGV)TINF2 [DGVbeta]
Mutations
ICGC Data PortalTINF2 
TCGA Data PortalTINF2 
Tumor PortalTINF2
Somatic Mutations in Cancer : COSMICTINF2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)14:24708851-24711880
CONAN: Copy Number AnalysisTINF2 
Mutations and Diseases : HGMDTINF2
OMIM127550    268130    604319    613990   
MedgenTINF2
NextProtQ9BSI4 [Medical]
GENETestsTINF2
Disease Genetic AssociationTINF2
Huge Navigator TINF2 [HugePedia]  TINF2 [HugeCancerGEM]
snp3D : Map Gene to Disease26277
DGIdb (Drug Gene Interaction db)TINF2
BioCentury BCIQTINF2
General knowledge
Homologs : HomoloGeneTINF2
Homology/Alignments : Family Browser (UCSC)TINF2
Phylogenetic Trees/Animal Genes : TreeFamTINF2
Chemical/Protein Interactions : CTD26277
Chemical/Pharm GKB GenePA36530
Clinical trialTINF2
Cancer Resource (Charite)ENSG00000092330
Other databases
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
CoreMineTINF2
GoPubMedTINF2
iHOPTINF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jun 27 12:24:33 CEST 2015

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