Identity
HGNC
LOCATION
1q24.2
LOCUSID
ALIAS
TIP,TIP41,TIPRL1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 261726
MIM: 611807
HGNC: 30231
Ensembl: ENSG00000143155
Variants:
dbSNP: 261726
ClinVar: 261726
TCGA: ENSG00000143155
COSMIC: TIPRL
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000143155 | ENST00000367830 | O75663 |
| ENSG00000143155 | ENST00000367833 | O75663 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31727942 | 2019 | The positive correlation of TIPRL with LC3 and CD133 contributes to cancer aggressiveness: potential biomarkers for early liver cancer. | 11 |
| 31862913 | 2019 | TIPRL potentiates survival of lung cancer by inducing autophagy through the eIF2α-ATF4 pathway. | 16 |
| 31727942 | 2019 | The positive correlation of TIPRL with LC3 and CD133 contributes to cancer aggressiveness: potential biomarkers for early liver cancer. | 11 |
| 31862913 | 2019 | TIPRL potentiates survival of lung cancer by inducing autophagy through the eIF2α-ATF4 pathway. | 16 |
| 30087317 | 2018 | Genetic association and meta-analysis of a schizophrenia GWAS variant rs10489202 in East Asian populations. | 3 |
| 30087317 | 2018 | Genetic association and meta-analysis of a schizophrenia GWAS variant rs10489202 in East Asian populations. | 3 |
| 26717153 | 2015 | TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response. | 12 |
| 26717153 | 2015 | TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response. | 12 |
| 22443683 | 2013 | The biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificity. | 101 |
| 23892082 | 2013 | A positive role of mammalian Tip41-like protein, TIPRL, in the amino-acid dependent mTORC1-signaling pathway through interaction with PP2A. | 26 |
| 22443683 | 2013 | The biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificity. | 101 |
| 23892082 | 2013 | A positive role of mammalian Tip41-like protein, TIPRL, in the amino-acid dependent mTORC1-signaling pathway through interaction with PP2A. | 26 |
| 22841785 | 2012 | Inhibition of MKK7-JNK by the TOR signaling pathway regulator-like protein contributes to resistance of HCC cells to TRAIL-induced apoptosis. | 25 |
| 22841785 | 2012 | Inhibition of MKK7-JNK by the TOR signaling pathway regulator-like protein contributes to resistance of HCC cells to TRAIL-induced apoptosis. | 25 |
| 19064610 | 2009 | Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation. | 16 |
Citation
Dessen P
TIPRL (TOR signaling pathway regulator)
Atlas Genet Cytogenet Oncol Haematol. 2013-02-01
Online version: http://atlasgeneticsoncology.org/gene/53169/tiprl
