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TLL1 (tolloid-like 1)

Identity

Other aliasASD6
TLL
HGNC (Hugo) TLL1
LocusID (NCBI) 7092
Atlas_Id 74723
Location 4q32.3  [Link to chromosome band 4q32]
Location_base_pair Starts at 166794410 and ends at 166952111 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TLL1   11843
Cards
Entrez_Gene (NCBI)TLL1  7092  tolloid-like 1
AliasesASD6; TLL
GeneCards (Weizmann)TLL1
Ensembl hg19 (Hinxton)ENSG00000038295 [Gene_View]  chr4:166794410-166952111 [Contig_View]  TLL1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000038295 [Gene_View]  chr4:166794410-166952111 [Contig_View]  TLL1 [Vega]
ICGC DataPortalENSG00000038295
TCGA cBioPortalTLL1
AceView (NCBI)TLL1
Genatlas (Paris)TLL1
WikiGenes7092
SOURCE (Princeton)TLL1
Genetics Home Reference (NIH)TLL1
Genomic and cartography
GoldenPath hg19 (UCSC)TLL1  -     chr4:166794410-166952111 +  4q32.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TLL1  -     4q32.3   [Description]    (hg38-Dec_2013)
EnsemblTLL1 - 4q32.3 [CytoView hg19]  TLL1 - 4q32.3 [CytoView hg38]
Mapping of homologs : NCBITLL1 [Mapview hg19]  TLL1 [Mapview hg38]
OMIM606742   613087   
Gene and transcription
Genbank (Entrez)AF282732 AK021908 BC016922 BC136429 BC136430
RefSeq transcript (Entrez)NM_001204760 NM_012464
RefSeq genomic (Entrez)NC_000004 NC_018915 NG_016278 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)TLL1
Cluster EST : UnigeneHs.106513 [ NCBI ]
CGAP (NCI)Hs.106513
Alternative Splicing GalleryENSG00000038295
Gene ExpressionTLL1 [ NCBI-GEO ]   TLL1 [ EBI - ARRAY_EXPRESS ]   TLL1 [ SEEK ]   TLL1 [ MEM ]
Gene Expression Viewer (FireBrowse)TLL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7092
GTEX Portal (Tissue expression)TLL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43897   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43897  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43897
Splice isoforms : SwissVarO43897
Catalytic activity : Enzyme3.4.24.- [ Enzyme-Expasy ]   3.4.24.-3.4.24.- [ IntEnz-EBI ]   3.4.24.- [ BRENDA ]   3.4.24.- [ KEGG ]   
PhosPhoSitePlusO43897
Domaine pattern : Prosite (Expaxy)CUB (PS01180)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)    ZINC_PROTEASE (PS00142)   
Domains : Interpro (EBI)BMP_1/tolloid-like    CUB_dom    EG-like_dom    EGF-like_Ca-bd_dom    EGF-like_CS    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    MetalloPept_cat_dom    Peptidase_M12A    Peptidase_Metallo   
Domain families : Pfam (Sanger)Astacin (PF01400)    CUB (PF00431)   
Domain families : Pfam (NCBI)pfam01400    pfam00431   
Domain families : Smart (EMBL)CUB (SM00042)  EGF_CA (SM00179)  ZnMc (SM00235)  
Conserved Domain (NCBI)TLL1
DMDM Disease mutations7092
Blocks (Seattle)TLL1
PDB (SRS)3EDI   
PDB (PDBSum)3EDI   
PDB (IMB)3EDI   
PDB (RSDB)3EDI   
Structural Biology KnowledgeBase3EDI   
SCOP (Structural Classification of Proteins)3EDI   
CATH (Classification of proteins structures)3EDI   
SuperfamilyO43897
Human Protein AtlasENSG00000038295
Peptide AtlasO43897
HPRD07074
IPIIPI00018381   IPI00718863   IPI00966186   IPI00922355   IPI00965411   IPI00966476   
Protein Interaction databases
DIP (DOE-UCLA)O43897
IntAct (EBI)O43897
FunCoupENSG00000038295
BioGRIDTLL1
STRING (EMBL)TLL1
ZODIACTLL1
Ontologies - Pathways
QuickGOO43897
Ontology : AmiGOskeletal system development  metalloendopeptidase activity  calcium ion binding  collagen binding  extracellular region  proteolysis  zinc ion binding  extracellular matrix disassembly  cell differentiation  extracellular matrix organization  
Ontology : EGO-EBIskeletal system development  metalloendopeptidase activity  calcium ion binding  collagen binding  extracellular region  proteolysis  zinc ion binding  extracellular matrix disassembly  cell differentiation  extracellular matrix organization  
NDEx NetworkTLL1
Atlas of Cancer Signalling NetworkTLL1
Wikipedia pathwaysTLL1
Orthology - Evolution
OrthoDB7092
GeneTree (enSembl)ENSG00000038295
Phylogenetic Trees/Animal Genes : TreeFamTLL1
HOVERGENO43897
HOGENOMO43897
Homologs : HomoloGeneTLL1
Homology/Alignments : Family Browser (UCSC)TLL1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTLL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TLL1
dbVarTLL1
ClinVarTLL1
1000_GenomesTLL1 
Exome Variant ServerTLL1
ExAC (Exome Aggregation Consortium)TLL1 (select the gene name)
Genetic variants : HAPMAP7092
Genomic Variants (DGV)TLL1 [DGVbeta]
DECIPHER (Syndromes)4:166794410-166952111  ENSG00000038295
CONAN: Copy Number AnalysisTLL1 
Mutations
ICGC Data PortalTLL1 
TCGA Data PortalTLL1 
Broad Tumor PortalTLL1
OASIS PortalTLL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTLL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTLL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TLL1
DgiDB (Drug Gene Interaction Database)TLL1
DoCM (Curated mutations)TLL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TLL1 (select a term)
intoGenTLL1
Cancer3DTLL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606742    613087   
Orphanet14123    14120   
MedgenTLL1
Genetic Testing Registry TLL1
NextProtO43897 [Medical]
TSGene7092
GENETestsTLL1
Huge Navigator TLL1 [HugePedia]
snp3D : Map Gene to Disease7092
BioCentury BCIQTLL1
ClinGenTLL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7092
Chemical/Pharm GKB GenePA36545
Clinical trialTLL1
Miscellaneous
canSAR (ICR)TLL1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTLL1
EVEXTLL1
GoPubMedTLL1
iHOPTLL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:48:12 CET 2017

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