TLN1 (talin 1)

Identity

Other names	ILWEQ
	KIAA1027
	TLN
HGNC	TLN1
Location	9p23-p21
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TLN1   11845
Entrez_Gene	TLN1  7094  talin 1
	Cards
GeneCards	TLN1
Ensembl	TLN1 [Search_View]   ENSG00000137076 [Gene_View]
Genatlas	TLN1
GeneLynx	TLN1
eGenome	TLN1
euGene	7094
	Genomic and cartography
GoldenPath	TLN1  -     chr9:35687334-35722128 -  9p13.3   [Description]    (hg18-March_2006)
Ensembl	TLN1 - 9p13.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TLN1
	Gene and transcription
Genbank	AB028950 [ ENTREZ ]
Genbank	AF078828 [ ENTREZ ]
Genbank	AF113217 [ ENTREZ ]
Genbank	AF177198 [ ENTREZ ]
Genbank	BC020881 [ ENTREZ ]
RefSeq	NM_006289 [ SRS ]    NM_006289 [ ENTREZ ]
RefSeq	AC_000052 [ SRS ]    AC_000052 [ ENTREZ ]
RefSeq	AC_000141 [ SRS ]    AC_000141 [ ENTREZ ]
RefSeq	NC_000009 [ SRS ]    NC_000009 [ ENTREZ ]
RefSeq	NT_008413 [ SRS ]    NT_008413 [ ENTREZ ]
RefSeq	NW_001839149 [ SRS ]    NW_001839149 [ ENTREZ ]
RefSeq	NW_924062 [ SRS ]    NW_924062 [ ENTREZ ]
AceView	TLN1 AceView - NCBI
Unigene	Hs.471014 [ SRS ]    Hs.471014 [ NCBI ]     HS471014 [ spliceNest ]
Fast-db	6532 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q5TCU5 [ SRS]    Q5TCU5 [ EXPASY ]     Q5TCU5 [ INTERPRO ]     Q5TCU5 [ UNIPROT ]
Prosite	PS00660 FERM_1 [ SRS ]    PS00660 FERM_1 [ Expasy ]
Prosite	PS50057 FERM_3 [ SRS ]    PS50057 FERM_3 [ Expasy ]
Interpro	IPR000299 Band_4.1_N [ SRS ]    IPR000299 Band_4.1_N [ EBI ]
Interpro	IPR014352 FERM/acyl-CoA_bd_prot_3-hlx [ SRS ]    IPR014352 FERM/acyl-CoA_bd_prot_3-hlx [ EBI ]
Interpro	IPR015710 Talin_rel [ SRS ]    IPR015710 Talin_rel [ EBI ]
CluSTr	Q5TCU5
Pfam	PF00373 Band_41 [ SRS ]    PF00373 Band_41 [ Sanger ]    pfam00373 [ NCBI-CDD ]
Smart	SM00295 B41 [EMBL]
Blocks	Q5TCU5
HPRD	01726
	Protein Interaction databases
DIP	Q5TCU5
IntAct	Q5TCU5
	Polymorphism : SNP, mutations, diseases
OMIM	186745    [ map ]
GENECLINICS	186745
SNP	TLN1 [dbSNP-NCBI]
SNP	NM_006289 [SNP-NCI]
SNP	TLN1 [GeneSNPs - Utah]  TLN1] [HGBASE - SRS]
HAPMAP	TLN1 [HAPMAP]
COSMIC	TLN1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	TLN1
	General knowledge
Family Browser	TLN1 [UCSC Family Browser]
SOURCE	NM_006289
SMD	Hs.471014
SAGE	Hs.471014
GO	ruffle [Amigo]  ruffle
GO	actin binding [Amigo]  actin binding
GO	structural constituent of cytoskeleton [Amigo]  structural constituent of cytoskeleton
GO	binding [Amigo]  binding
GO	protein binding [Amigo]  protein binding
GO	cytoplasm [Amigo]  cytoplasm
GO	cytoskeleton [Amigo]  cytoskeleton
GO	intercellular junction [Amigo]  intercellular junction
GO	focal adhesion [Amigo]  focal adhesion
GO	cell motility [Amigo]  cell motility
GO	cytoskeletal anchoring at plasma membrane [Amigo]  cytoskeletal anchoring at plasma membrane
GO	cell-cell junction assembly [Amigo]  cell-cell junction assembly
GO	membrane [Amigo]  membrane
GO	vinculin binding [Amigo]  vinculin binding
GO	LIM domain binding [Amigo]  LIM domain binding
BIOCARTA	Apoptotic Signaling in Response to DNA Damage    [Genes]
BIOCARTA	Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia    [Genes]
BIOCARTA	Integrin Signaling Pathway    [Genes]
BIOCARTA	mCalpain and friends in Cell motility    [Genes]
BIOCARTA	Rho cell motility signaling pathway    [Genes]
BIOCARTA	uCalpain and friends in Cell spread    [Genes]
KEGG	Focal adhesion
PubGene	TLN1
TreeFam	TLN1
CTD	7094 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TLN1 Related clones (RZPD - Berlin)
	PubMed
PubMed	48 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:35:13 2008