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TLR10 (toll like receptor 10)

Identity

Alias_namestoll-like receptor 10
Alias_symbol (synonym)CD290
Other alias
HGNC (Hugo) TLR10
LocusID (NCBI) 81793
Atlas_Id 46568
Location 4p14  [Link to chromosome band 4p14]
Location_base_pair Starts at 38772239 and ends at 38782990 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TLR10   15634
Cards
Entrez_Gene (NCBI)TLR10  81793  toll like receptor 10
AliasesCD290
GeneCards (Weizmann)TLR10
Ensembl hg19 (Hinxton)ENSG00000174123 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174123 [Gene_View]  chr4:38772239-38782990 [Contig_View]  TLR10 [Vega]
ICGC DataPortalENSG00000174123
TCGA cBioPortalTLR10
AceView (NCBI)TLR10
Genatlas (Paris)TLR10
WikiGenes81793
SOURCE (Princeton)TLR10
Genetics Home Reference (NIH)TLR10
Genomic and cartography
GoldenPath hg38 (UCSC)TLR10  -     chr4:38772239-38782990 -  4p14   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TLR10  -     4p14   [Description]    (hg19-Feb_2009)
EnsemblTLR10 - 4p14 [CytoView hg19]  TLR10 - 4p14 [CytoView hg38]
Mapping of homologs : NCBITLR10 [Mapview hg19]  TLR10 [Mapview hg38]
OMIM606270   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001017388 NM_001195106 NM_001195107 NM_001195108 NM_030956
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TLR10
Cluster EST : UnigeneHs.730896 [ NCBI ]
CGAP (NCI)Hs.730896
Alternative Splicing GalleryENSG00000174123
Gene ExpressionTLR10 [ NCBI-GEO ]   TLR10 [ EBI - ARRAY_EXPRESS ]   TLR10 [ SEEK ]   TLR10 [ MEM ]
Gene Expression Viewer (FireBrowse)TLR10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81793
GTEX Portal (Tissue expression)TLR10
Human Protein AtlasENSG00000174123-TLR10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BXR5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BXR5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BXR5
Splice isoforms : SwissVarQ9BXR5
PhosPhoSitePlusQ9BXR5
Domaine pattern : Prosite (Expaxy)LRR (PS51450)    TIR (PS50104)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    TIR_dom    TLR10    Toll-like_receptor   
Domain families : Pfam (Sanger)LRR_1 (PF00560)    LRR_8 (PF13855)    TIR (PF01582)   
Domain families : Pfam (NCBI)pfam00560    pfam13855    pfam01582   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  TIR (SM00255)  
Conserved Domain (NCBI)TLR10
DMDM Disease mutations81793
Blocks (Seattle)TLR10
PDB (SRS)2J67   
PDB (PDBSum)2J67   
PDB (IMB)2J67   
PDB (RSDB)2J67   
Structural Biology KnowledgeBase2J67   
SCOP (Structural Classification of Proteins)2J67   
CATH (Classification of proteins structures)2J67   
SuperfamilyQ9BXR5
Human Protein Atlas [tissue]ENSG00000174123-TLR10 [tissue]
Peptide AtlasQ9BXR5
HPRD05884
IPIIPI00008887   IPI00967572   
Protein Interaction databases
DIP (DOE-UCLA)Q9BXR5
IntAct (EBI)Q9BXR5
FunCoupENSG00000174123
BioGRIDTLR10
STRING (EMBL)TLR10
ZODIACTLR10
Ontologies - Pathways
QuickGOQ9BXR5
Ontology : AmiGOtoll-like receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  transmembrane signaling receptor activity  plasma membrane  integral component of plasma membrane  inflammatory response  immune response  membrane  toll-like receptor 10 signaling pathway  innate immune response  regulation of cytokine secretion  positive regulation of inflammatory response  
Ontology : EGO-EBItoll-like receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  transmembrane signaling receptor activity  plasma membrane  integral component of plasma membrane  inflammatory response  immune response  membrane  toll-like receptor 10 signaling pathway  innate immune response  regulation of cytokine secretion  positive regulation of inflammatory response  
NDEx NetworkTLR10
Atlas of Cancer Signalling NetworkTLR10
Wikipedia pathwaysTLR10
Orthology - Evolution
OrthoDB81793
GeneTree (enSembl)ENSG00000174123
Phylogenetic Trees/Animal Genes : TreeFamTLR10
HOVERGENQ9BXR5
HOGENOMQ9BXR5
Homologs : HomoloGeneTLR10
Homology/Alignments : Family Browser (UCSC)TLR10
Gene fusions - Rearrangements
Tumor Fusion PortalTLR10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTLR10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TLR10
dbVarTLR10
ClinVarTLR10
1000_GenomesTLR10 
Exome Variant ServerTLR10
ExAC (Exome Aggregation Consortium)ENSG00000174123
GNOMAD BrowserENSG00000174123
Genetic variants : HAPMAP81793
Genomic Variants (DGV)TLR10 [DGVbeta]
DECIPHERTLR10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTLR10 
Mutations
ICGC Data PortalTLR10 
TCGA Data PortalTLR10 
Broad Tumor PortalTLR10
OASIS PortalTLR10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTLR10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTLR10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TLR10
DgiDB (Drug Gene Interaction Database)TLR10
DoCM (Curated mutations)TLR10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TLR10 (select a term)
intoGenTLR10
Cancer3DTLR10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606270   
Orphanet
DisGeNETTLR10
MedgenTLR10
Genetic Testing Registry TLR10
NextProtQ9BXR5 [Medical]
TSGene81793
GENETestsTLR10
Target ValidationTLR10
Huge Navigator TLR10 [HugePedia]
snp3D : Map Gene to Disease81793
BioCentury BCIQTLR10
ClinGenTLR10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81793
Chemical/Pharm GKB GenePA38011
Clinical trialTLR10
Miscellaneous
canSAR (ICR)TLR10 (select the gene name)
Probes
Litterature
PubMed84 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTLR10
EVEXTLR10
GoPubMedTLR10
iHOPTLR10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:38:34 CET 2017

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