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TLR10 (toll like receptor 10)

Identity

Alias (NCBI)CD290
HGNC (Hugo) TLR10
HGNC Alias symbCD290
HGNC Previous nametoll-like receptor 10
LocusID (NCBI) 81793
Atlas_Id 46568
Location 4p14  [Link to chromosome band 4p14]
Location_base_pair Starts at 38772238 and ends at 38782990 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TLR10   15634
Cards
Entrez_Gene (NCBI)TLR10    toll like receptor 10
AliasesCD290
GeneCards (Weizmann)TLR10
Ensembl hg19 (Hinxton)ENSG00000174123 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174123 [Gene_View]  ENSG00000174123 [Sequence]  chr4:38772238-38782990 [Contig_View]  TLR10 [Vega]
ICGC DataPortalENSG00000174123
TCGA cBioPortalTLR10
AceView (NCBI)TLR10
Genatlas (Paris)TLR10
SOURCE (Princeton)TLR10
Genetics Home Reference (NIH)TLR10
Genomic and cartography
GoldenPath hg38 (UCSC)TLR10  -     chr4:38772238-38782990 -  4p14   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TLR10  -     4p14   [Description]    (hg19-Feb_2009)
GoldenPathTLR10 - 4p14 [CytoView hg19]  TLR10 - 4p14 [CytoView hg38]
ImmunoBaseENSG00000174123
Genome Data Viewer NCBITLR10 [Mapview hg19]  
OMIM606270   
Gene and transcription
Genbank (Entrez)AB445680 AF296673 AK292026 AK313468 AW504309
RefSeq transcript (Entrez)NM_001017388 NM_001195106 NM_001195107 NM_001195108 NM_030956
Consensus coding sequences : CCDS (NCBI)TLR10
Gene ExpressionTLR10 [ NCBI-GEO ]   TLR10 [ EBI - ARRAY_EXPRESS ]   TLR10 [ SEEK ]   TLR10 [ MEM ]
Gene Expression Viewer (FireBrowse)TLR10 [ Firebrowse - Broad ]
GenevisibleExpression of TLR10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81793
GTEX Portal (Tissue expression)TLR10
Human Protein AtlasENSG00000174123-TLR10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BXR5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BXR5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BXR5
PhosPhoSitePlusQ9BXR5
Domaine pattern : Prosite (Expaxy)LRR (PS51450)    TIR (PS50104)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR_dom_sf    TIR_dom    TLR10    Toll-like_receptor    Toll_tir_struct_dom_sf   
Domain families : Pfam (Sanger)LRR_1 (PF00560)    LRR_8 (PF13855)    TIR (PF01582)   
Domain families : Pfam (NCBI)pfam00560    pfam13855    pfam01582   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  TIR (SM00255)  
Conserved Domain (NCBI)TLR10
PDB (RSDB)2J67   
PDB Europe2J67   
PDB (PDBSum)2J67   
PDB (IMB)2J67   
Structural Biology KnowledgeBase2J67   
SCOP (Structural Classification of Proteins)2J67   
CATH (Classification of proteins structures)2J67   
SuperfamilyQ9BXR5
AlphaFold pdb e-kbQ9BXR5   
Human Protein Atlas [tissue]ENSG00000174123-TLR10 [tissue]
HPRD05884
Protein Interaction databases
DIP (DOE-UCLA)Q9BXR5
IntAct (EBI)Q9BXR5
BioGRIDTLR10
STRING (EMBL)TLR10
ZODIACTLR10
Ontologies - Pathways
QuickGOQ9BXR5
Ontology : AmiGOregulation of cytokine production  toll-like receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  transmembrane signaling receptor activity  protein binding  plasma membrane  integral component of plasma membrane  inflammatory response  immune response  membrane  toll-like receptor 10 signaling pathway  signaling receptor activity  identical protein binding  innate immune response  NAD(P)+ nucleosidase activity  positive regulation of inflammatory response  NAD+ nucleotidase, cyclic ADP-ribose generating  
Ontology : EGO-EBIregulation of cytokine production  toll-like receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  transmembrane signaling receptor activity  protein binding  plasma membrane  integral component of plasma membrane  inflammatory response  immune response  membrane  toll-like receptor 10 signaling pathway  signaling receptor activity  identical protein binding  innate immune response  NAD(P)+ nucleosidase activity  positive regulation of inflammatory response  NAD+ nucleotidase, cyclic ADP-ribose generating  
NDEx NetworkTLR10
Atlas of Cancer Signalling NetworkTLR10
Wikipedia pathwaysTLR10
Orthology - Evolution
OrthoDB81793
GeneTree (enSembl)ENSG00000174123
Phylogenetic Trees/Animal Genes : TreeFamTLR10
Homologs : HomoloGeneTLR10
Homology/Alignments : Family Browser (UCSC)TLR10
Gene fusions - Rearrangements
Fusion : QuiverTLR10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTLR10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TLR10
dbVarTLR10
ClinVarTLR10
MonarchTLR10
1000_GenomesTLR10 
Exome Variant ServerTLR10
GNOMAD BrowserENSG00000174123
Varsome BrowserTLR10
ACMGTLR10 variants
VarityQ9BXR5
Genomic Variants (DGV)TLR10 [DGVbeta]
DECIPHERTLR10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTLR10 
Mutations
ICGC Data PortalTLR10 
TCGA Data PortalTLR10 
Broad Tumor PortalTLR10
OASIS PortalTLR10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTLR10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTLR10
Mutations and Diseases : HGMDTLR10
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTLR10
DgiDB (Drug Gene Interaction Database)TLR10
DoCM (Curated mutations)TLR10
CIViC (Clinical Interpretations of Variants in Cancer)TLR10
Cancer3DTLR10
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606270   
Orphanet
DisGeNETTLR10
MedgenTLR10
Genetic Testing Registry TLR10
NextProtQ9BXR5 [Medical]
GENETestsTLR10
Target ValidationTLR10
Huge Navigator TLR10 [HugePedia]
ClinGenTLR10
Clinical trials, drugs, therapy
MyCancerGenomeTLR10
Protein Interactions : CTDTLR10
Pharm GKB GenePA38011
PharosQ9BXR5
Clinical trialTLR10
Miscellaneous
canSAR (ICR)TLR10
HarmonizomeTLR10
DataMed IndexTLR10
Probes
Litterature
PubMed115 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTLR10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:35:14 CEST 2021

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