TM4SF20 (transmembrane 4 L six family member 20)

2016-08-01  

Identity

HGNC
TM4SF20
LOCATION
2q36.3
LOCUSID
79853
ALIAS
PRO994,SLI5,TCCE518

Other Information

Locus ID:

NCBI: 79853
MIM: 615404
HGNC: 26230
Ensembl: ENSG00000168955

Variants:

dbSNP: 79853
ClinVar: 79853
TCGA: ENSG00000168955
COSMIC: TM4SF20

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168955ENST00000304568Q53R12
ENSG00000168955ENST00000449706C9JES4

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
204797602011Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia.100
238103812013TM4SF20 ancestral deletion and susceptibility to a pediatric disorder of early language delay and cerebral white matter hyperintensities.14
274992932016Inverting the Topology of a Transmembrane Protein by Regulating the Translocation of the First Transmembrane Helix.9
274992932016Inverting the Topology of a Transmembrane Protein by Regulating the Translocation of the First Transmembrane Helix.9
308087122019Identification of residues critical for topology inversion of the transmembrane protein TM4SF20 through regulated alternative translocation.1

Citation

Dessen P

TM4SF20 (transmembrane 4 L six family member 20)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55911/tm4sf20