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TM6SF2 (transmembrane 6 superfamily member 2)

Identity

Alias_symbol (synonym)Lpr4
Other alias-
HGNC (Hugo) TM6SF2
LocusID (NCBI) 53345
Atlas_Id 74737
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 19264365 and ends at 19273265 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TM6SF2   11861
Cards
Entrez_Gene (NCBI)TM6SF2  53345  transmembrane 6 superfamily member 2
Aliases
GeneCards (Weizmann)TM6SF2
Ensembl hg19 (Hinxton)ENSG00000213996 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000213996 [Gene_View]  chr19:19264365-19273265 [Contig_View]  TM6SF2 [Vega]
ICGC DataPortalENSG00000213996
TCGA cBioPortalTM6SF2
AceView (NCBI)TM6SF2
Genatlas (Paris)TM6SF2
WikiGenes53345
SOURCE (Princeton)TM6SF2
Genetics Home Reference (NIH)TM6SF2
Genomic and cartography
GoldenPath hg38 (UCSC)TM6SF2  -     chr19:19264365-19273265 -  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TM6SF2  -     19p13.11   [Description]    (hg19-Feb_2009)
EnsemblTM6SF2 - 19p13.11 [CytoView hg19]  TM6SF2 - 19p13.11 [CytoView hg38]
Mapping of homologs : NCBITM6SF2 [Mapview hg19]  TM6SF2 [Mapview hg38]
OMIM606563   
Gene and transcription
Genbank (Entrez)AF255923 AK024515 AK026307 AK097070 BC120986
RefSeq transcript (Entrez)NM_001001524 NM_203510
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TM6SF2
Cluster EST : UnigeneHs.531624 [ NCBI ]
CGAP (NCI)Hs.531624
Alternative Splicing GalleryENSG00000213996
Gene ExpressionTM6SF2 [ NCBI-GEO ]   TM6SF2 [ EBI - ARRAY_EXPRESS ]   TM6SF2 [ SEEK ]   TM6SF2 [ MEM ]
Gene Expression Viewer (FireBrowse)TM6SF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)53345
GTEX Portal (Tissue expression)TM6SF2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BZW4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BZW4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BZW4
Splice isoforms : SwissVarQ9BZW4
PhosPhoSitePlusQ9BZW4
Domaine pattern : Prosite (Expaxy)EXPERA (PS51751)   
Domains : Interpro (EBI)EXPERA   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TM6SF2
DMDM Disease mutations53345
Blocks (Seattle)TM6SF2
SuperfamilyQ9BZW4
Human Protein AtlasENSG00000213996
Peptide AtlasQ9BZW4
HPRD12109
IPIIPI00478358   IPI00556355   IPI00787386   
Protein Interaction databases
DIP (DOE-UCLA)Q9BZW4
IntAct (EBI)Q9BZW4
FunCoupENSG00000213996
BioGRIDTM6SF2
STRING (EMBL)TM6SF2
ZODIACTM6SF2
Ontologies - Pathways
QuickGOQ9BZW4
Ontology : AmiGOmolecular_function  endoplasmic reticulum membrane  lipid metabolic process  biological_process  integral component of membrane  regulation of lipid metabolic process  endoplasmic reticulum-Golgi intermediate compartment membrane  
Ontology : EGO-EBImolecular_function  endoplasmic reticulum membrane  lipid metabolic process  biological_process  integral component of membrane  regulation of lipid metabolic process  endoplasmic reticulum-Golgi intermediate compartment membrane  
NDEx NetworkTM6SF2
Atlas of Cancer Signalling NetworkTM6SF2
Wikipedia pathwaysTM6SF2
Orthology - Evolution
OrthoDB53345
GeneTree (enSembl)ENSG00000213996
Phylogenetic Trees/Animal Genes : TreeFamTM6SF2
HOVERGENQ9BZW4
HOGENOMQ9BZW4
Homologs : HomoloGeneTM6SF2
Homology/Alignments : Family Browser (UCSC)TM6SF2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTM6SF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TM6SF2
dbVarTM6SF2
ClinVarTM6SF2
1000_GenomesTM6SF2 
Exome Variant ServerTM6SF2
ExAC (Exome Aggregation Consortium)TM6SF2 (select the gene name)
Genetic variants : HAPMAP53345
Genomic Variants (DGV)TM6SF2 [DGVbeta]
DECIPHERTM6SF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTM6SF2 
Mutations
ICGC Data PortalTM6SF2 
TCGA Data PortalTM6SF2 
Broad Tumor PortalTM6SF2
OASIS PortalTM6SF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTM6SF2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTM6SF2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TM6SF2
DgiDB (Drug Gene Interaction Database)TM6SF2
DoCM (Curated mutations)TM6SF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TM6SF2 (select a term)
intoGenTM6SF2
Cancer3DTM6SF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606563   
Orphanet
MedgenTM6SF2
Genetic Testing Registry TM6SF2
NextProtQ9BZW4 [Medical]
TSGene53345
GENETestsTM6SF2
Target ValidationTM6SF2
Huge Navigator TM6SF2 [HugePedia]
snp3D : Map Gene to Disease53345
BioCentury BCIQTM6SF2
ClinGenTM6SF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD53345
Chemical/Pharm GKB GenePA36562
Clinical trialTM6SF2
Miscellaneous
canSAR (ICR)TM6SF2 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTM6SF2
EVEXTM6SF2
GoPubMedTM6SF2
iHOPTM6SF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:45:40 CEST 2017

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