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TM6SF2 (transmembrane 6 superfamily member 2)

Identity

Other alias-
HGNC (Hugo) TM6SF2
LocusID (NCBI) 53345
Atlas_Id 57136
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 19264366 and ends at 19273214 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TM6SF2   11861
Cards
Entrez_Gene (NCBI)TM6SF2  53345  transmembrane 6 superfamily member 2
Aliases
GeneCards (Weizmann)TM6SF2
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr19:19264366-19273214 [Contig_View]  TM6SF2 [Vega]
TCGA cBioPortalTM6SF2
AceView (NCBI)TM6SF2
Genatlas (Paris)TM6SF2
WikiGenes53345
SOURCE (Princeton)TM6SF2
Genetics Home Reference (NIH)TM6SF2
Genomic and cartography
GoldenPath hg38 (UCSC)TM6SF2  -     chr19:19264366-19273214 -  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TM6SF2  -     19p13.11   [Description]    (hg19-Feb_2009)
EnsemblTM6SF2 - 19p13.11 [CytoView hg19]  TM6SF2 - 19p13.11 [CytoView hg38]
Mapping of homologs : NCBITM6SF2 [Mapview hg19]  TM6SF2 [Mapview hg38]
OMIM606563   
Gene and transcription
Genbank (Entrez)AF255923 AK024515 AK026307 AK097070 BC120986
RefSeq transcript (Entrez)NM_001001524 NM_203510
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TM6SF2
Cluster EST : UnigeneHs.531624 [ NCBI ]
CGAP (NCI)Hs.531624
Gene ExpressionTM6SF2 [ NCBI-GEO ]   TM6SF2 [ EBI - ARRAY_EXPRESS ]   TM6SF2 [ SEEK ]   TM6SF2 [ MEM ]
Gene Expression Viewer (FireBrowse)TM6SF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)53345
GTEX Portal (Tissue expression)TM6SF2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BZW4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BZW4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BZW4
Splice isoforms : SwissVarQ9BZW4
PhosPhoSitePlusQ9BZW4
Domaine pattern : Prosite (Expaxy)EXPERA (PS51751)   
Domains : Interpro (EBI)EXPERA   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TM6SF2
DMDM Disease mutations53345
Blocks (Seattle)TM6SF2
SuperfamilyQ9BZW4
Peptide AtlasQ9BZW4
IPIIPI00478358   IPI00556355   IPI00787386   
Protein Interaction databases
DIP (DOE-UCLA)Q9BZW4
IntAct (EBI)Q9BZW4
BioGRIDTM6SF2
STRING (EMBL)TM6SF2
ZODIACTM6SF2
Ontologies - Pathways
QuickGOQ9BZW4
Ontology : AmiGOmolecular_function  endoplasmic reticulum membrane  lipid metabolic process  integral component of membrane  regulation of lipid metabolic process  endoplasmic reticulum-Golgi intermediate compartment membrane  
Ontology : EGO-EBImolecular_function  endoplasmic reticulum membrane  lipid metabolic process  integral component of membrane  regulation of lipid metabolic process  endoplasmic reticulum-Golgi intermediate compartment membrane  
NDEx NetworkTM6SF2
Atlas of Cancer Signalling NetworkTM6SF2
Wikipedia pathwaysTM6SF2
Orthology - Evolution
OrthoDB53345
Phylogenetic Trees/Animal Genes : TreeFamTM6SF2
HOVERGENQ9BZW4
HOGENOMQ9BZW4
Homologs : HomoloGeneTM6SF2
Homology/Alignments : Family Browser (UCSC)TM6SF2
Gene fusions - Rearrangements
Tumor Fusion PortalTM6SF2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTM6SF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TM6SF2
dbVarTM6SF2
ClinVarTM6SF2
1000_GenomesTM6SF2 
Exome Variant ServerTM6SF2
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP53345
Genomic Variants (DGV)TM6SF2 [DGVbeta]
DECIPHERTM6SF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTM6SF2 
Mutations
ICGC Data PortalTM6SF2 
TCGA Data PortalTM6SF2 
Broad Tumor PortalTM6SF2
OASIS PortalTM6SF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTM6SF2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTM6SF2
BioMutasearch TM6SF2
DgiDB (Drug Gene Interaction Database)TM6SF2
DoCM (Curated mutations)TM6SF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TM6SF2 (select a term)
intoGenTM6SF2
Cancer3DTM6SF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606563   
Orphanet
DisGeNETTM6SF2
MedgenTM6SF2
Genetic Testing Registry TM6SF2
NextProtQ9BZW4 [Medical]
TSGene53345
GENETestsTM6SF2
Target ValidationTM6SF2
Huge Navigator TM6SF2 [HugePedia]
snp3D : Map Gene to Disease53345
BioCentury BCIQTM6SF2
ClinGenTM6SF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD53345
Chemical/Pharm GKB GenePA36562
Clinical trialTM6SF2
Miscellaneous
canSAR (ICR)TM6SF2 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTM6SF2
EVEXTM6SF2
GoPubMedTM6SF2
iHOPTM6SF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Nov 21 14:38:38 CET 2017

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