Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TM7SF3 (transmembrane 7 superfamily member 3)

Identity

Alias (NCBI)-
HGNC (Hugo) TM7SF3
LocusID (NCBI) 51768
Atlas_Id 54701
Location 12p11.23  [Link to chromosome band 12p11]
Location_base_pair Starts at 26971584 and ends at 27014384 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CLEC16A (16p13.13) / TM7SF3 (12p11.23)LDLRAD3 (11p13) / TM7SF3 (12p11.23)SAP30BP (17q25.1) / TM7SF3 (12p11.23)
TM7SF3 (12p11.23) / C12orf42 (12q23.2)TM7SF3 (12p11.23) / SSBP1 (7q34)LDLRAD3 11p13 / TM7SF3 12p11.23
TM7SF3 12p11.23 / C12orf42 12q23.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(11;12)(p13;p11) LDLRAD3/TM7SF3
t(12;12)(p11;q23) TM7SF3/C12orf42

External links

Nomenclature
HGNC (Hugo)TM7SF3   23049
Cards
Entrez_Gene (NCBI)TM7SF3  51768  transmembrane 7 superfamily member 3
Aliases
GeneCards (Weizmann)TM7SF3
Ensembl hg19 (Hinxton)ENSG00000064115 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000064115 [Gene_View]  ENSG00000064115 [Sequence]  chr12:26971584-27014384 [Contig_View]  TM7SF3 [Vega]
ICGC DataPortalENSG00000064115
TCGA cBioPortalTM7SF3
AceView (NCBI)TM7SF3
Genatlas (Paris)TM7SF3
WikiGenes51768
SOURCE (Princeton)TM7SF3
Genetics Home Reference (NIH)TM7SF3
Genomic and cartography
GoldenPath hg38 (UCSC)TM7SF3  -     chr12:26971584-27014384 -  12p11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TM7SF3  -     12p11.23   [Description]    (hg19-Feb_2009)
GoldenPathTM7SF3 - 12p11.23 [CytoView hg19]  TM7SF3 - 12p11.23 [CytoView hg38]
ImmunoBaseENSG00000064115
genome Data Viewer NCBITM7SF3 [Mapview hg19]  
OMIM605181   
Gene and transcription
Genbank (Entrez)AB032470 AK002031 AK023085 AK091115 BC005176
RefSeq transcript (Entrez)NM_016551
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TM7SF3
Alternative Splicing GalleryENSG00000064115
Gene ExpressionTM7SF3 [ NCBI-GEO ]   TM7SF3 [ EBI - ARRAY_EXPRESS ]   TM7SF3 [ SEEK ]   TM7SF3 [ MEM ]
Gene Expression Viewer (FireBrowse)TM7SF3 [ Firebrowse - Broad ]
GenevisibleExpression of TM7SF3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51768
GTEX Portal (Tissue expression)TM7SF3
Human Protein AtlasENSG00000064115-TM7SF3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NS93   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NS93  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NS93
Splice isoforms : SwissVarQ9NS93
PhosPhoSitePlusQ9NS93
Domains : Interpro (EBI)DUF4203    TM7SF3   
Domain families : Pfam (Sanger)DUF4203 (PF13886)   
Domain families : Pfam (NCBI)pfam13886   
Conserved Domain (NCBI)TM7SF3
DMDM Disease mutations51768
Blocks (Seattle)TM7SF3
SuperfamilyQ9NS93
Human Protein Atlas [tissue]ENSG00000064115-TM7SF3 [tissue]
Peptide AtlasQ9NS93
HPRD05536
IPIIPI00009797   IPI01014397   IPI01013223   IPI01013618   IPI01012098   IPI01012505   IPI01011250   IPI01011677   IPI01010862   IPI01009609   IPI01010019   IPI01015752   IPI01009195   IPI01014977   
Protein Interaction databases
DIP (DOE-UCLA)Q9NS93
IntAct (EBI)Q9NS93
FunCoupENSG00000064115
BioGRIDTM7SF3
STRING (EMBL)TM7SF3
ZODIACTM7SF3
Ontologies - Pathways
QuickGOQ9NS93
Ontology : AmiGOmolecular_function  plasma membrane  integral component of membrane  positive regulation of insulin secretion  cellular response to unfolded protein  negative regulation of programmed cell death  extracellular exosome  
Ontology : EGO-EBImolecular_function  plasma membrane  integral component of membrane  positive regulation of insulin secretion  cellular response to unfolded protein  negative regulation of programmed cell death  extracellular exosome  
NDEx NetworkTM7SF3
Atlas of Cancer Signalling NetworkTM7SF3
Wikipedia pathwaysTM7SF3
Orthology - Evolution
OrthoDB51768
GeneTree (enSembl)ENSG00000064115
Phylogenetic Trees/Animal Genes : TreeFamTM7SF3
HOGENOMQ9NS93
Homologs : HomoloGeneTM7SF3
Homology/Alignments : Family Browser (UCSC)TM7SF3
Gene fusions - Rearrangements
Fusion : MitelmanLDLRAD3/TM7SF3 [11p13/12p11.23]  
Fusion : MitelmanTM7SF3/C12orf42 [12p11.23/12q23.2]  
Fusion PortalLDLRAD3 11p13 TM7SF3 12p11.23 LUAD
Fusion PortalTM7SF3 12p11.23 C12orf42 12q23.2 GBM
Fusion : QuiverTM7SF3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTM7SF3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TM7SF3
dbVarTM7SF3
ClinVarTM7SF3
MonarchTM7SF3
1000_GenomesTM7SF3 
Exome Variant ServerTM7SF3
GNOMAD BrowserENSG00000064115
Varsome BrowserTM7SF3
Genetic variants : HAPMAP51768
Genomic Variants (DGV)TM7SF3 [DGVbeta]
DECIPHERTM7SF3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTM7SF3 
Mutations
ICGC Data PortalTM7SF3 
TCGA Data PortalTM7SF3 
Broad Tumor PortalTM7SF3
OASIS PortalTM7SF3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTM7SF3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTM7SF3
Mutations and Diseases : HGMDTM7SF3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TM7SF3
DgiDB (Drug Gene Interaction Database)TM7SF3
DoCM (Curated mutations)TM7SF3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TM7SF3 (select a term)
intoGenTM7SF3
Cancer3DTM7SF3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605181   
Orphanet
DisGeNETTM7SF3
MedgenTM7SF3
Genetic Testing Registry TM7SF3
NextProtQ9NS93 [Medical]
TSGene51768
GENETestsTM7SF3
Target ValidationTM7SF3
Huge Navigator TM7SF3 [HugePedia]
snp3D : Map Gene to Disease51768
BioCentury BCIQTM7SF3
ClinGenTM7SF3
Clinical trials, drugs, therapy
Protein Interactions : CTD51768
Pharm GKB GenePA134949354
Clinical trialTM7SF3
Miscellaneous
canSAR (ICR)TM7SF3 (select the gene name)
HarmonizomeTM7SF3
DataMed IndexTM7SF3
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTM7SF3
EVEXTM7SF3
GoPubMedTM7SF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Sep 14 14:36:16 CEST 2020
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