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TM9SF4 (transmembrane 9 superfamily member 4)

Identity

Alias_symbol (synonym)KIAA0255
dJ836N17.2
Other alias
HGNC (Hugo) TM9SF4
LocusID (NCBI) 9777
Atlas_Id 51410
Location 20q11.21  [Link to chromosome band 20q11]
Location_base_pair Starts at 32109506 and ends at 32167258 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ASXL1 (20q11.21) / TM9SF4 (20q11.21)CALD1 (7q33) / TM9SF4 (20q11.21)MAPRE1 (20q11.21) / TM9SF4 (20q11.21)
POFUT1 (20q11.21) / TM9SF4 (20q11.21)RPL8 (8q24.3) / TM9SF4 (20q11.21)TM9SF4 (20q11.21) / ARPC1B (7q22.1)
TM9SF4 (20q11.21) / CALD1 (7q33)TM9SF4 (20q11.21) / CRTC3 (15q26.1)TM9SF4 (20q11.21) / EYA2 (20q13.12)
TM9SF4 (20q11.21) / HM13 (20q11.21)TM9SF4 (20q11.21) / NKTR (3p22.1)TM9SF4 (20q11.21) / OSER1 (20q13.12)
TM9SF4 (20q11.21) / TM9SF4 (20q11.21)TM9SF4 (20q11.21) / TPX2 (20q11.21)TM9SF4 (20q11.21) / TUBA4A (2q35)
TM9SF4 (20q11.21) / ZNF423 (16q12.1)ASXL1 20q11.21 / TM9SF4 20q11.21MAPRE1 20q11.21 / TM9SF4 20q11.21
TM9SF4 20q11.21 / EYA2 20q13.12TM9SF4 20q11.21 / HM13 20q11.21TM9SF4 20q11.21 / TPX2 20q11.21
TM9SF4 20q11.21 / ZNF423 16q12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TM9SF4   30797
Cards
Entrez_Gene (NCBI)TM9SF4  9777  transmembrane 9 superfamily member 4
AliasesdJ836N17.2
GeneCards (Weizmann)TM9SF4
Ensembl hg19 (Hinxton)ENSG00000101337 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101337 [Gene_View]  chr20:32109506-32167258 [Contig_View]  TM9SF4 [Vega]
ICGC DataPortalENSG00000101337
TCGA cBioPortalTM9SF4
AceView (NCBI)TM9SF4
Genatlas (Paris)TM9SF4
WikiGenes9777
SOURCE (Princeton)TM9SF4
Genetics Home Reference (NIH)TM9SF4
Genomic and cartography
GoldenPath hg38 (UCSC)TM9SF4  -     chr20:32109506-32167258 +  20q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TM9SF4  -     20q11.21   [Description]    (hg19-Feb_2009)
EnsemblTM9SF4 - 20q11.21 [CytoView hg19]  TM9SF4 - 20q11.21 [CytoView hg38]
Mapping of homologs : NCBITM9SF4 [Mapview hg19]  TM9SF4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK124411 AK126534 AK294980 AK296500 AK302439
RefSeq transcript (Entrez)NM_014742
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TM9SF4
Cluster EST : UnigeneHs.654665 [ NCBI ]
CGAP (NCI)Hs.654665
Alternative Splicing GalleryENSG00000101337
Gene ExpressionTM9SF4 [ NCBI-GEO ]   TM9SF4 [ EBI - ARRAY_EXPRESS ]   TM9SF4 [ SEEK ]   TM9SF4 [ MEM ]
Gene Expression Viewer (FireBrowse)TM9SF4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9777
GTEX Portal (Tissue expression)TM9SF4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92544   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92544  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92544
Splice isoforms : SwissVarQ92544
PhosPhoSitePlusQ92544
Domains : Interpro (EBI)EMP70   
Domain families : Pfam (Sanger)EMP70 (PF02990)   
Domain families : Pfam (NCBI)pfam02990   
Conserved Domain (NCBI)TM9SF4
DMDM Disease mutations9777
Blocks (Seattle)TM9SF4
SuperfamilyQ92544
Human Protein AtlasENSG00000101337
Peptide AtlasQ92544
HPRD15514
IPIIPI00021985   IPI00909581   IPI00445136   IPI00885106   IPI00894462   IPI00893914   
Protein Interaction databases
DIP (DOE-UCLA)Q92544
IntAct (EBI)Q92544
FunCoupENSG00000101337
BioGRIDTM9SF4
STRING (EMBL)TM9SF4
ZODIACTM9SF4
Ontologies - Pathways
QuickGOQ92544
Ontology : AmiGOresponse to hypoxia  protein binding  early endosome  Golgi apparatus  phagocytosis  cell adhesion  integral component of membrane  regulation of intracellular pH  vacuolar proton-transporting V-type ATPase complex assembly  positive regulation of protein exit from endoplasmic reticulum  positive regulation of protein localization to cell surface  
Ontology : EGO-EBIresponse to hypoxia  protein binding  early endosome  Golgi apparatus  phagocytosis  cell adhesion  integral component of membrane  regulation of intracellular pH  vacuolar proton-transporting V-type ATPase complex assembly  positive regulation of protein exit from endoplasmic reticulum  positive regulation of protein localization to cell surface  
NDEx NetworkTM9SF4
Atlas of Cancer Signalling NetworkTM9SF4
Wikipedia pathwaysTM9SF4
Orthology - Evolution
OrthoDB9777
GeneTree (enSembl)ENSG00000101337
Phylogenetic Trees/Animal Genes : TreeFamTM9SF4
HOVERGENQ92544
HOGENOMQ92544
Homologs : HomoloGeneTM9SF4
Homology/Alignments : Family Browser (UCSC)TM9SF4
Gene fusions - Rearrangements
Fusion : MitelmanASXL1/TM9SF4 [20q11.21/20q11.21]  [t(20;20)(q11;q11)]  
Fusion : MitelmanMAPRE1/TM9SF4 [20q11.21/20q11.21]  [t(20;20)(q11;q11)]  
Fusion : MitelmanTM9SF4/EYA2 [20q11.21/20q13.12]  [t(20;20)(q11;q13)]  
Fusion : MitelmanTM9SF4/HM13 [20q11.21/20q11.21]  [t(20;20)(q11;q11)]  
Fusion : MitelmanTM9SF4/TPX2 [20q11.21/20q11.21]  [t(20;20)(q11;q11)]  
Fusion : MitelmanTM9SF4/ZNF423 [20q11.21/16q12.1]  [t(16;20)(q12;q11)]  
Fusion: TCGAASXL1 20q11.21 TM9SF4 20q11.21 BRCA LUAD
Fusion: TCGAMAPRE1 20q11.21 TM9SF4 20q11.21 PRAD
Fusion: TCGATM9SF4 20q11.21 EYA2 20q13.12 LUAD
Fusion: TCGATM9SF4 20q11.21 HM13 20q11.21 GBM LUSC
Fusion: TCGATM9SF4 20q11.21 TPX2 20q11.21 BRCA
Fusion: TCGATM9SF4 20q11.21 ZNF423 16q12.1 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTM9SF4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TM9SF4
dbVarTM9SF4
ClinVarTM9SF4
1000_GenomesTM9SF4 
Exome Variant ServerTM9SF4
ExAC (Exome Aggregation Consortium)TM9SF4 (select the gene name)
Genetic variants : HAPMAP9777
Genomic Variants (DGV)TM9SF4 [DGVbeta]
DECIPHERTM9SF4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTM9SF4 
Mutations
ICGC Data PortalTM9SF4 
TCGA Data PortalTM9SF4 
Broad Tumor PortalTM9SF4
OASIS PortalTM9SF4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTM9SF4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTM9SF4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TM9SF4
DgiDB (Drug Gene Interaction Database)TM9SF4
DoCM (Curated mutations)TM9SF4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TM9SF4 (select a term)
intoGenTM9SF4
Cancer3DTM9SF4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTM9SF4
Genetic Testing Registry TM9SF4
NextProtQ92544 [Medical]
TSGene9777
GENETestsTM9SF4
Target ValidationTM9SF4
Huge Navigator TM9SF4 [HugePedia]
snp3D : Map Gene to Disease9777
BioCentury BCIQTM9SF4
ClinGenTM9SF4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9777
Chemical/Pharm GKB GenePA134937613
Clinical trialTM9SF4
Miscellaneous
canSAR (ICR)TM9SF4 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTM9SF4
EVEXTM9SF4
GoPubMedTM9SF4
iHOPTM9SF4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:59:34 CEST 2017

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