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TMC5 (transmembrane channel like 5)

Identity

Alias_symbol (synonym)FLJ13593
Other alias-
HGNC (Hugo) TMC5
LocusID (NCBI) 79838
Atlas_Id 74746
Location 16p12.3  [Link to chromosome band 16p12]
Location_base_pair Starts at 19410735 and ends at 19499112 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
C16orf62 (16p12.3) / TMC5 (16p12.3)COL12A1 (6q13) / TMC5 (16p12.3)LRRC29 (16q22.1) / TMC5 (16p12.3)
MALAT1 (11q13.1) / TMC5 (16p12.3)TMC5 (16p12.3) / CCP110 (16p12.3)TMC5 (16p12.3) / TMC5 (16p12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMC5   22999
Cards
Entrez_Gene (NCBI)TMC5  79838  transmembrane channel like 5
Aliases
GeneCards (Weizmann)TMC5
Ensembl hg19 (Hinxton)ENSG00000103534 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000103534 [Gene_View]  chr16:19410735-19499112 [Contig_View]  TMC5 [Vega]
ICGC DataPortalENSG00000103534
TCGA cBioPortalTMC5
AceView (NCBI)TMC5
Genatlas (Paris)TMC5
WikiGenes79838
SOURCE (Princeton)TMC5
Genetics Home Reference (NIH)TMC5
Genomic and cartography
GoldenPath hg38 (UCSC)TMC5  -     chr16:19410735-19499112 +  16p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMC5  -     16p12.3   [Description]    (hg19-Feb_2009)
EnsemblTMC5 - 16p12.3 [CytoView hg19]  TMC5 - 16p12.3 [CytoView hg38]
Mapping of homologs : NCBITMC5 [Mapview hg19]  TMC5 [Mapview hg38]
OMIM617197   
Gene and transcription
Genbank (Entrez)AI738488 AK023655 AK093944 AK097718 AK131202
RefSeq transcript (Entrez)NM_001105248 NM_001105249 NM_001261841 NM_001308161 NM_024780
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMC5
Cluster EST : UnigeneHs.115838 [ NCBI ]
CGAP (NCI)Hs.115838
Alternative Splicing GalleryENSG00000103534
Gene ExpressionTMC5 [ NCBI-GEO ]   TMC5 [ EBI - ARRAY_EXPRESS ]   TMC5 [ SEEK ]   TMC5 [ MEM ]
Gene Expression Viewer (FireBrowse)TMC5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79838
GTEX Portal (Tissue expression)TMC5
Human Protein AtlasENSG00000103534-TMC5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UXY8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UXY8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UXY8
Splice isoforms : SwissVarQ6UXY8
PhosPhoSitePlusQ6UXY8
Domains : Interpro (EBI)TMC   
Domain families : Pfam (Sanger)TMC (PF07810)   
Domain families : Pfam (NCBI)pfam07810   
Conserved Domain (NCBI)TMC5
DMDM Disease mutations79838
Blocks (Seattle)TMC5
SuperfamilyQ6UXY8
Human Protein Atlas [tissue]ENSG00000103534-TMC5 [tissue]
Peptide AtlasQ6UXY8
HPRD15516
IPIIPI00470897   IPI00432771   IPI00220470   IPI00644372   IPI00902696   IPI00922799   
Protein Interaction databases
DIP (DOE-UCLA)Q6UXY8
IntAct (EBI)Q6UXY8
FunCoupENSG00000103534
BioGRIDTMC5
STRING (EMBL)TMC5
ZODIACTMC5
Ontologies - Pathways
QuickGOQ6UXY8
Ontology : AmiGOion transport  integral component of membrane  extracellular exosome  
Ontology : EGO-EBIion transport  integral component of membrane  extracellular exosome  
NDEx NetworkTMC5
Atlas of Cancer Signalling NetworkTMC5
Wikipedia pathwaysTMC5
Orthology - Evolution
OrthoDB79838
GeneTree (enSembl)ENSG00000103534
Phylogenetic Trees/Animal Genes : TreeFamTMC5
HOVERGENQ6UXY8
HOGENOMQ6UXY8
Homologs : HomoloGeneTMC5
Homology/Alignments : Family Browser (UCSC)TMC5
Gene fusions - Rearrangements
Fusion: Tumor Portal TMC5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMC5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMC5
dbVarTMC5
ClinVarTMC5
1000_GenomesTMC5 
Exome Variant ServerTMC5
ExAC (Exome Aggregation Consortium)ENSG00000103534
GNOMAD BrowserENSG00000103534
Genetic variants : HAPMAP79838
Genomic Variants (DGV)TMC5 [DGVbeta]
DECIPHERTMC5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMC5 
Mutations
ICGC Data PortalTMC5 
TCGA Data PortalTMC5 
Broad Tumor PortalTMC5
OASIS PortalTMC5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMC5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMC5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMC5
DgiDB (Drug Gene Interaction Database)TMC5
DoCM (Curated mutations)TMC5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMC5 (select a term)
intoGenTMC5
Cancer3DTMC5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617197   
Orphanet
MedgenTMC5
Genetic Testing Registry TMC5
NextProtQ6UXY8 [Medical]
TSGene79838
GENETestsTMC5
Target ValidationTMC5
Huge Navigator TMC5 [HugePedia]
snp3D : Map Gene to Disease79838
BioCentury BCIQTMC5
ClinGenTMC5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79838
Chemical/Pharm GKB GenePA134923498
Clinical trialTMC5
Miscellaneous
canSAR (ICR)TMC5 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMC5
EVEXTMC5
GoPubMedTMC5
iHOPTMC5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:32:33 CET 2017

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