Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TMED2 (transmembrane p24 trafficking protein 2)

Identity

Alias_namestransmembrane emp24 domain trafficking protein 2
Alias_symbol (synonym)RNP24
P24A
p24beta1
p24b1
Other aliasp24
HGNC (Hugo) TMED2
LocusID (NCBI) 10959
Atlas_Id 52521
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 124069076 and ends at 124082688 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MDK (11p11.2) / TMED2 (12q24.31)TMED2 (12q24.31) / PARM1 (4q13.3)TMED2 (12q24.31) / PPIA (7p13)
TMED2 (12q24.31) / TMED2 (12q24.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMED2   16996
Cards
Entrez_Gene (NCBI)TMED2  10959  transmembrane p24 trafficking protein 2
AliasesP24A; RNP24; p24; p24b1; 
p24beta1
GeneCards (Weizmann)TMED2
Ensembl hg19 (Hinxton)ENSG00000086598 [Gene_View]  chr12:124069076-124082688 [Contig_View]  TMED2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000086598 [Gene_View]  chr12:124069076-124082688 [Contig_View]  TMED2 [Vega]
ICGC DataPortalENSG00000086598
TCGA cBioPortalTMED2
AceView (NCBI)TMED2
Genatlas (Paris)TMED2
WikiGenes10959
SOURCE (Princeton)TMED2
Genetics Home Reference (NIH)TMED2
Genomic and cartography
GoldenPath hg19 (UCSC)TMED2  -     chr12:124069076-124082688 +  12q24.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TMED2  -     12q24.31   [Description]    (hg38-Dec_2013)
EnsemblTMED2 - 12q24.31 [CytoView hg19]  TMED2 - 12q24.31 [CytoView hg38]
Mapping of homologs : NCBITMED2 [Mapview hg19]  TMED2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AI954929 AK024976 AK298167 AK303189 AK312975
RefSeq transcript (Entrez)NM_001321445 NM_006815
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929386
Consensus coding sequences : CCDS (NCBI)TMED2
Cluster EST : UnigeneHs.733403 [ NCBI ]
CGAP (NCI)Hs.733403
Alternative Splicing GalleryENSG00000086598
Gene ExpressionTMED2 [ NCBI-GEO ]   TMED2 [ EBI - ARRAY_EXPRESS ]   TMED2 [ SEEK ]   TMED2 [ MEM ]
Gene Expression Viewer (FireBrowse)TMED2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10959
GTEX Portal (Tissue expression)TMED2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15363   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15363  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15363
Splice isoforms : SwissVarQ15363
PhosPhoSitePlusQ15363
Domaine pattern : Prosite (Expaxy)GOLD (PS50866)   
Domains : Interpro (EBI)GOLD_dom   
Domain families : Pfam (Sanger)EMP24_GP25L (PF01105)   
Domain families : Pfam (NCBI)pfam01105   
Conserved Domain (NCBI)TMED2
DMDM Disease mutations10959
Blocks (Seattle)TMED2
SuperfamilyQ15363
Human Protein AtlasENSG00000086598
Peptide AtlasQ15363
HPRD17984
IPIIPI00016608   IPI00797864   IPI00909375   IPI01012491   
Protein Interaction databases
DIP (DOE-UCLA)Q15363
IntAct (EBI)Q15363
FunCoupENSG00000086598
BioGRIDTMED2
STRING (EMBL)TMED2
ZODIACTMED2
Ontologies - Pathways
QuickGOQ15363
Ontology : AmiGOGolgi membrane  neural tube closure  maternal placenta development  heart looping  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum-Golgi intermediate compartment  Golgi apparatus  intracellular protein transport  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  Golgi organization  positive regulation of gene expression  ER to Golgi transport vesicle membrane  integral component of membrane  transport vesicle  COPI-coated vesicle  COPI-coated vesicle membrane  somite rostral/caudal axis specification  Golgi cisterna membrane  endoplasmic reticulum-Golgi intermediate compartment membrane  negative regulation of GTPase activity  multicellular organism growth  cargo loading into vesicle  post-anal tail morphogenesis  zymogen granule membrane  intracellular membrane-bounded organelle  COPI coating of Golgi vesicle  COPII vesicle coating  labyrinthine layer blood vessel development  protein targeting to plasma membrane  
Ontology : EGO-EBIGolgi membrane  neural tube closure  maternal placenta development  heart looping  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum-Golgi intermediate compartment  Golgi apparatus  intracellular protein transport  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  Golgi organization  positive regulation of gene expression  ER to Golgi transport vesicle membrane  integral component of membrane  transport vesicle  COPI-coated vesicle  COPI-coated vesicle membrane  somite rostral/caudal axis specification  Golgi cisterna membrane  endoplasmic reticulum-Golgi intermediate compartment membrane  negative regulation of GTPase activity  multicellular organism growth  cargo loading into vesicle  post-anal tail morphogenesis  zymogen granule membrane  intracellular membrane-bounded organelle  COPI coating of Golgi vesicle  COPII vesicle coating  labyrinthine layer blood vessel development  protein targeting to plasma membrane  
NDEx NetworkTMED2
Atlas of Cancer Signalling NetworkTMED2
Wikipedia pathwaysTMED2
Orthology - Evolution
OrthoDB10959
GeneTree (enSembl)ENSG00000086598
Phylogenetic Trees/Animal Genes : TreeFamTMED2
HOVERGENQ15363
HOGENOMQ15363
Homologs : HomoloGeneTMED2
Homology/Alignments : Family Browser (UCSC)TMED2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMED2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMED2
dbVarTMED2
ClinVarTMED2
1000_GenomesTMED2 
Exome Variant ServerTMED2
ExAC (Exome Aggregation Consortium)TMED2 (select the gene name)
Genetic variants : HAPMAP10959
Genomic Variants (DGV)TMED2 [DGVbeta]
DECIPHER (Syndromes)12:124069076-124082688  ENSG00000086598
CONAN: Copy Number AnalysisTMED2 
Mutations
ICGC Data PortalTMED2 
TCGA Data PortalTMED2 
Broad Tumor PortalTMED2
OASIS PortalTMED2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMED2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMED2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMED2
DgiDB (Drug Gene Interaction Database)TMED2
DoCM (Curated mutations)TMED2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMED2 (select a term)
intoGenTMED2
Cancer3DTMED2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTMED2
Genetic Testing Registry TMED2
NextProtQ15363 [Medical]
TSGene10959
GENETestsTMED2
Huge Navigator TMED2 [HugePedia]
snp3D : Map Gene to Disease10959
BioCentury BCIQTMED2
ClinGenTMED2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10959
Chemical/Pharm GKB GenePA142670796
Clinical trialTMED2
Miscellaneous
canSAR (ICR)TMED2 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMED2
EVEXTMED2
GoPubMedTMED2
iHOPTMED2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:31:20 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.