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TMED6 (transmembrane p24 trafficking protein 6)

Identity

Alias_namestransmembrane emp24 protein transport domain containing 6
Alias_symbol (synonym)MGC23911
p24gamma5
p24g5
Other aliasPRO34237
SPLL9146
HGNC (Hugo) TMED6
LocusID (NCBI) 146456
Atlas_Id 55682
Location 16q22.1  [Link to chromosome band 16q22]
Location_base_pair Starts at 69343246 and ends at 69351809 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TMED6   28331
Cards
Entrez_Gene (NCBI)TMED6  146456  transmembrane p24 trafficking protein 6
AliasesPRO34237; SPLL9146; p24g5
GeneCards (Weizmann)TMED6
Ensembl hg19 (Hinxton)ENSG00000157315 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000157315 [Gene_View]  ENSG00000157315 [Sequence]  chr16:69343246-69351809 [Contig_View]  TMED6 [Vega]
ICGC DataPortalENSG00000157315
TCGA cBioPortalTMED6
AceView (NCBI)TMED6
Genatlas (Paris)TMED6
WikiGenes146456
SOURCE (Princeton)TMED6
Genetics Home Reference (NIH)TMED6
Genomic and cartography
GoldenPath hg38 (UCSC)TMED6  -     chr16:69343246-69351809 -  16q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMED6  -     16q22.1   [Description]    (hg19-Feb_2009)
GoldenPathTMED6 - 16q22.1 [CytoView hg19]  TMED6 - 16q22.1 [CytoView hg38]
ImmunoBaseENSG00000157315
Mapping of homologs : NCBITMED6 [Mapview hg19]  TMED6 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA804957 AY358268 BC020827 BI600655
RefSeq transcript (Entrez)NM_144676
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMED6
Cluster EST : UnigeneHs.729118 [ NCBI ]
CGAP (NCI)Hs.729118
Alternative Splicing GalleryENSG00000157315
Gene ExpressionTMED6 [ NCBI-GEO ]   TMED6 [ EBI - ARRAY_EXPRESS ]   TMED6 [ SEEK ]   TMED6 [ MEM ]
Gene Expression Viewer (FireBrowse)TMED6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)146456
GTEX Portal (Tissue expression)TMED6
Human Protein AtlasENSG00000157315-TMED6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WW62   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WW62  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WW62
Splice isoforms : SwissVarQ8WW62
PhosPhoSitePlusQ8WW62
Domaine pattern : Prosite (Expaxy)GOLD (PS50866)   
Domains : Interpro (EBI)GOLD_dom    TMP21-related   
Domain families : Pfam (Sanger)EMP24_GP25L (PF01105)   
Domain families : Pfam (NCBI)pfam01105   
Domain families : Smart (EMBL)EMP24_GP25L (SM01190)  
Conserved Domain (NCBI)TMED6
DMDM Disease mutations146456
Blocks (Seattle)TMED6
SuperfamilyQ8WW62
Human Protein Atlas [tissue]ENSG00000157315-TMED6 [tissue]
Peptide AtlasQ8WW62
HPRD15520
IPIIPI00103251   
Protein Interaction databases
DIP (DOE-UCLA)Q8WW62
IntAct (EBI)Q8WW62
FunCoupENSG00000157315
BioGRIDTMED6
STRING (EMBL)TMED6
ZODIACTMED6
Ontologies - Pathways
QuickGOQ8WW62
Ontology : AmiGOendoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum-Golgi intermediate compartment  Golgi apparatus  intracellular protein transport  ER to Golgi vesicle-mediated transport  Golgi organization  integral component of membrane  COPII-coated ER to Golgi transport vesicle  
Ontology : EGO-EBIendoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum-Golgi intermediate compartment  Golgi apparatus  intracellular protein transport  ER to Golgi vesicle-mediated transport  Golgi organization  integral component of membrane  COPII-coated ER to Golgi transport vesicle  
NDEx NetworkTMED6
Atlas of Cancer Signalling NetworkTMED6
Wikipedia pathwaysTMED6
Orthology - Evolution
OrthoDB146456
GeneTree (enSembl)ENSG00000157315
Phylogenetic Trees/Animal Genes : TreeFamTMED6
HOGENOMQ8WW62
Homologs : HomoloGeneTMED6
Homology/Alignments : Family Browser (UCSC)TMED6
Gene fusions - Rearrangements
Fusion : QuiverTMED6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMED6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMED6
dbVarTMED6
ClinVarTMED6
1000_GenomesTMED6 
Exome Variant ServerTMED6
ExAC (Exome Aggregation Consortium)ENSG00000157315
GNOMAD BrowserENSG00000157315
Varsome BrowserTMED6
Genetic variants : HAPMAP146456
Genomic Variants (DGV)TMED6 [DGVbeta]
DECIPHERTMED6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMED6 
Mutations
ICGC Data PortalTMED6 
TCGA Data PortalTMED6 
Broad Tumor PortalTMED6
OASIS PortalTMED6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMED6  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMED6
Mutations and Diseases : HGMDTMED6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMED6
DgiDB (Drug Gene Interaction Database)TMED6
DoCM (Curated mutations)TMED6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMED6 (select a term)
intoGenTMED6
Cancer3DTMED6(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTMED6
MedgenTMED6
Genetic Testing Registry TMED6
NextProtQ8WW62 [Medical]
TSGene146456
GENETestsTMED6
Target ValidationTMED6
Huge Navigator TMED6 [HugePedia]
snp3D : Map Gene to Disease146456
BioCentury BCIQTMED6
ClinGenTMED6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD146456
Chemical/Pharm GKB GenePA128394759
Clinical trialTMED6
Miscellaneous
canSAR (ICR)TMED6 (select the gene name)
DataMed IndexTMED6
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMED6
EVEXTMED6
GoPubMedTMED6
iHOPTMED6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Feb 3 15:29:03 CET 2020
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