Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TMEM104 (transmembrane protein 104)

Identity

Alias (NCBI)-
HGNC (Hugo) TMEM104
HGNC Alias symbFLJ20255
FLJ00021
LocusID (NCBI) 54868
Atlas_Id 54704
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 74776499 and ends at 74839753 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ENDOV (17q25.3) / TMEM104 (17q25.1)KCTD2 (17q25.1) / TMEM104 (17q25.1)TMEM104 (17q25.1) / CDK12 (17q12)
TMEM104 (17q25.1) / DNAI2 (17q25.1)TMEM104 (17q25.1) / NF1 (17q11.2)TMEM104 (17q25.1) / PPP2R4 (9q34.11)
TMEM104 (17q25.1) / RAB37 (17q25.1)TMEM104 (17q25.1) / SLC9A3R1 (17q25.1)TRPM7 (15q21.2) / TMEM104 (17q25.1)
ENDOV 17q25.3 / TMEM104 17q25.1KCTD2 17q25.1 / TMEM104 17q25.1TMEM104 17q25.1 / DNAI2 17q25.1
TMEM104 17q25.1 / RAB37 17q25.1TRPM7 15q21.2 / TMEM104 17q25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TMEM104   25984
Cards
Entrez_Gene (NCBI)TMEM104    transmembrane protein 104
Aliases
GeneCards (Weizmann)TMEM104
Ensembl hg19 (Hinxton)ENSG00000109066 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000109066 [Gene_View]  ENSG00000109066 [Sequence]  chr17:74776499-74839753 [Contig_View]  TMEM104 [Vega]
ICGC DataPortalENSG00000109066
TCGA cBioPortalTMEM104
AceView (NCBI)TMEM104
Genatlas (Paris)TMEM104
SOURCE (Princeton)TMEM104
Genetics Home Reference (NIH)TMEM104
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM104  -     chr17:74776499-74839753 +  17q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM104  -     17q25.1   [Description]    (hg19-Feb_2009)
GoldenPathTMEM104 - 17q25.1 [CytoView hg19]  TMEM104 - 17q25.1 [CytoView hg38]
ImmunoBaseENSG00000109066
genome Data Viewer NCBITMEM104 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK000262 AK074029 AK291159 AK296621 AL137521
RefSeq transcript (Entrez)NM_001321264 NM_017728
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM104
Alternative Splicing GalleryENSG00000109066
Gene ExpressionTMEM104 [ NCBI-GEO ]   TMEM104 [ EBI - ARRAY_EXPRESS ]   TMEM104 [ SEEK ]   TMEM104 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM104 [ Firebrowse - Broad ]
GenevisibleExpression of TMEM104 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54868
GTEX Portal (Tissue expression)TMEM104
Human Protein AtlasENSG00000109066-TMEM104 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NE00   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NE00  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NE00
Splice isoforms : SwissVarQ8NE00
PhosPhoSitePlusQ8NE00
Domains : Interpro (EBI)AA_transpt_TM   
Domain families : Pfam (Sanger)Aa_trans (PF01490)   
Domain families : Pfam (NCBI)pfam01490   
Conserved Domain (NCBI)TMEM104
Blocks (Seattle)TMEM104
SuperfamilyQ8NE00
Human Protein Atlas [tissue]ENSG00000109066-TMEM104 [tissue]
Peptide AtlasQ8NE00
HPRD07888
IPIIPI00291835   IPI00793242   IPI01017994   
Protein Interaction databases
DIP (DOE-UCLA)Q8NE00
IntAct (EBI)Q8NE00
BioGRIDTMEM104
STRING (EMBL)TMEM104
ZODIACTMEM104
Ontologies - Pathways
QuickGOQ8NE00
Ontology : AmiGOmolecular_function  cellular_component  biological_process  integral component of membrane  
Ontology : EGO-EBImolecular_function  cellular_component  biological_process  integral component of membrane  
NDEx NetworkTMEM104
Atlas of Cancer Signalling NetworkTMEM104
Wikipedia pathwaysTMEM104
Orthology - Evolution
OrthoDB54868
GeneTree (enSembl)ENSG00000109066
Phylogenetic Trees/Animal Genes : TreeFamTMEM104
HOGENOMQ8NE00
Homologs : HomoloGeneTMEM104
Homology/Alignments : Family Browser (UCSC)TMEM104
Gene fusions - Rearrangements
Fusion : MitelmanENDOV/TMEM104 [17q25.3/17q25.1]  
Fusion : MitelmanKCTD2/TMEM104 [17q25.1/17q25.1]  
Fusion : MitelmanTMEM104/CDK12 [17q25.1/17q12]  
Fusion : MitelmanTMEM104/DNAI2 [17q25.1/17q25.1]  
Fusion : MitelmanTMEM104/RAB37 [17q25.1/17q25.1]  
Fusion : MitelmanTRPM7/TMEM104 [15q21.2/17q25.1]  
Fusion PortalENDOV 17q25.3 TMEM104 17q25.1 KIRC
Fusion PortalKCTD2 17q25.1 TMEM104 17q25.1 LUAD
Fusion PortalTMEM104 17q25.1 DNAI2 17q25.1 BRCA
Fusion PortalTMEM104 17q25.1 RAB37 17q25.1 LUAD
Fusion PortalTRPM7 15q21.2 TMEM104 17q25.1 BRCA
Fusion : QuiverTMEM104
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM104 [hg38]
dbVarTMEM104
ClinVarTMEM104
MonarchTMEM104
1000_GenomesTMEM104 
Exome Variant ServerTMEM104
GNOMAD BrowserENSG00000109066
Varsome BrowserTMEM104
Genomic Variants (DGV)TMEM104 [DGVbeta]
DECIPHERTMEM104 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM104 
Mutations
ICGC Data PortalTMEM104 
TCGA Data PortalTMEM104 
Broad Tumor PortalTMEM104
OASIS PortalTMEM104 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM104  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM104
Mutations and Diseases : HGMDTMEM104
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM104
DgiDB (Drug Gene Interaction Database)TMEM104
DoCM (Curated mutations)TMEM104 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM104 (select a term)
intoGenTMEM104
Cancer3DTMEM104(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTMEM104
MedgenTMEM104
Genetic Testing Registry TMEM104
NextProtQ8NE00 [Medical]
GENETestsTMEM104
Target ValidationTMEM104
Huge Navigator TMEM104 [HugePedia]
ClinGenTMEM104
Clinical trials, drugs, therapy
MyCancerGenomeTMEM104
Protein Interactions : CTD
Pharm GKB GenePA142670753
PharosQ8NE00
Clinical trialTMEM104
Miscellaneous
canSAR (ICR)TMEM104 (select the gene name)
HarmonizomeTMEM104
DataMed IndexTMEM104
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTMEM104
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:49:53 CET 2021
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