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TMEM106B (transmembrane protein 106B)

Identity

Alias_symbol (synonym)MGC33727
FLJ11273
Other alias-
HGNC (Hugo) TMEM106B
LocusID (NCBI) 54664
Atlas_Id 74773
Location 7p21.3  [Link to chromosome band 7p21]
Location_base_pair Starts at 12250848 and ends at 12276890 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DNAJC21 (5p13.2) / TMEM106B (7p21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMEM106B   22407
Cards
Entrez_Gene (NCBI)TMEM106B  54664  transmembrane protein 106B
Aliases
GeneCards (Weizmann)TMEM106B
Ensembl hg19 (Hinxton) [Gene_View]  chr7:12250848-12276890 [Contig_View]  TMEM106B [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr7:12250848-12276890 [Contig_View]  TMEM106B [Vega]
TCGA cBioPortalTMEM106B
AceView (NCBI)TMEM106B
Genatlas (Paris)TMEM106B
WikiGenes54664
SOURCE (Princeton)TMEM106B
Genetics Home Reference (NIH)TMEM106B
Genomic and cartography
GoldenPath hg19 (UCSC)TMEM106B  -     chr7:12250848-12276890 +  7p21.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TMEM106B  -     7p21.3   [Description]    (hg38-Dec_2013)
EnsemblTMEM106B - 7p21.3 [CytoView hg19]  TMEM106B - 7p21.3 [CytoView hg38]
Mapping of homologs : NCBITMEM106B [Mapview hg19]  TMEM106B [Mapview hg38]
OMIM613413   
Gene and transcription
Genbank (Entrez)AK001834 AK002135 AK090805 AK223263 AK311651
RefSeq transcript (Entrez)NM_001134232 NM_018374
RefSeq genomic (Entrez)NC_000007 NC_018918 NT_007819 NW_004929329
Consensus coding sequences : CCDS (NCBI)TMEM106B
Cluster EST : UnigeneHs.396358 [ NCBI ]
CGAP (NCI)Hs.396358
Gene ExpressionTMEM106B [ NCBI-GEO ]   TMEM106B [ EBI - ARRAY_EXPRESS ]   TMEM106B [ SEEK ]   TMEM106B [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM106B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54664
GTEX Portal (Tissue expression)TMEM106B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NUM4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NUM4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NUM4
Splice isoforms : SwissVarQ9NUM4
PhosPhoSitePlusQ9NUM4
Domains : Interpro (EBI)DUF1356_TMEM106   
Domain families : Pfam (Sanger)DUF1356 (PF07092)   
Domain families : Pfam (NCBI)pfam07092   
Conserved Domain (NCBI)TMEM106B
DMDM Disease mutations54664
Blocks (Seattle)TMEM106B
SuperfamilyQ9NUM4
Peptide AtlasQ9NUM4
HPRD07745
IPIIPI00395903   IPI00893001   IPI00892634   IPI00893365   
Protein Interaction databases
DIP (DOE-UCLA)Q9NUM4
IntAct (EBI)Q9NUM4
BioGRIDTMEM106B
STRING (EMBL)TMEM106B
ZODIACTMEM106B
Ontologies - Pathways
QuickGOQ9NUM4
Ontology : AmiGOmolecular_function  protein binding  lysosomal membrane  transport  integral component of membrane  late endosome membrane  lysosome localization  intracellular membrane-bounded organelle  dendrite morphogenesis  extracellular exosome  
Ontology : EGO-EBImolecular_function  protein binding  lysosomal membrane  transport  integral component of membrane  late endosome membrane  lysosome localization  intracellular membrane-bounded organelle  dendrite morphogenesis  extracellular exosome  
NDEx NetworkTMEM106B
Atlas of Cancer Signalling NetworkTMEM106B
Wikipedia pathwaysTMEM106B
Orthology - Evolution
OrthoDB54664
Phylogenetic Trees/Animal Genes : TreeFamTMEM106B
HOVERGENQ9NUM4
HOGENOMQ9NUM4
Homologs : HomoloGeneTMEM106B
Homology/Alignments : Family Browser (UCSC)TMEM106B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM106B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM106B
dbVarTMEM106B
ClinVarTMEM106B
1000_GenomesTMEM106B 
Exome Variant ServerTMEM106B
ExAC (Exome Aggregation Consortium)TMEM106B (select the gene name)
Genetic variants : HAPMAP54664
Genomic Variants (DGV)TMEM106B [DGVbeta]
DECIPHER (Syndromes)7:12250848-12276890  
CONAN: Copy Number AnalysisTMEM106B 
Mutations
ICGC Data PortalTMEM106B 
TCGA Data PortalTMEM106B 
Broad Tumor PortalTMEM106B
OASIS PortalTMEM106B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM106B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM106B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM106B
DgiDB (Drug Gene Interaction Database)TMEM106B
DoCM (Curated mutations)TMEM106B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM106B (select a term)
intoGenTMEM106B
Cancer3DTMEM106B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613413   
Orphanet
MedgenTMEM106B
Genetic Testing Registry TMEM106B
NextProtQ9NUM4 [Medical]
TSGene54664
GENETestsTMEM106B
Huge Navigator TMEM106B [HugePedia]
snp3D : Map Gene to Disease54664
BioCentury BCIQTMEM106B
ClinGenTMEM106B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54664
Chemical/Pharm GKB GenePA142670756
Clinical trialTMEM106B
Miscellaneous
canSAR (ICR)TMEM106B (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM106B
EVEXTMEM106B
GoPubMedTMEM106B
iHOPTMEM106B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:48:22 CET 2017

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