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TMEM106C (transmembrane protein 106C)

Identity

Alias_symbol (synonym)MGC5576
Other alias-
HGNC (Hugo) TMEM106C
LocusID (NCBI) 79022
Atlas_Id 74774
Location 12q13.11  [Link to chromosome band 12q13]
Location_base_pair Starts at 47963547 and ends at 47968878 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
COPB2 (3q23) / TMEM106C (12q13.11)NDUFAF5 (20p12.1) / TMEM106C (12q13.11)TMEM106C (12q13.11) / IFRD2 (3p21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMEM106C   28775
Cards
Entrez_Gene (NCBI)TMEM106C  79022  transmembrane protein 106C
Aliases
GeneCards (Weizmann)TMEM106C
Ensembl hg19 (Hinxton)ENSG00000134291 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134291 [Gene_View]  chr12:47963547-47968878 [Contig_View]  TMEM106C [Vega]
ICGC DataPortalENSG00000134291
TCGA cBioPortalTMEM106C
AceView (NCBI)TMEM106C
Genatlas (Paris)TMEM106C
WikiGenes79022
SOURCE (Princeton)TMEM106C
Genetics Home Reference (NIH)TMEM106C
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM106C  -     chr12:47963547-47968878 +  12q13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM106C  -     12q13.11   [Description]    (hg19-Feb_2009)
EnsemblTMEM106C - 12q13.11 [CytoView hg19]  TMEM106C - 12q13.11 [CytoView hg38]
Mapping of homologs : NCBITMEM106C [Mapview hg19]  TMEM106C [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK299154 AK310035 AK313698 BC000854 BC107792
RefSeq transcript (Entrez)NM_001143841 NM_001143842 NM_001143843 NM_001143844 NM_001143845 NM_024056
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM106C
Cluster EST : UnigeneHs.596726 [ NCBI ]
CGAP (NCI)Hs.596726
Alternative Splicing GalleryENSG00000134291
Gene ExpressionTMEM106C [ NCBI-GEO ]   TMEM106C [ EBI - ARRAY_EXPRESS ]   TMEM106C [ SEEK ]   TMEM106C [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM106C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79022
GTEX Portal (Tissue expression)TMEM106C
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BVX2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BVX2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BVX2
Splice isoforms : SwissVarQ9BVX2
PhosPhoSitePlusQ9BVX2
Domains : Interpro (EBI)DUF1356_TMEM106   
Domain families : Pfam (Sanger)DUF1356 (PF07092)   
Domain families : Pfam (NCBI)pfam07092   
Conserved Domain (NCBI)TMEM106C
DMDM Disease mutations79022
Blocks (Seattle)TMEM106C
SuperfamilyQ9BVX2
Human Protein AtlasENSG00000134291
Peptide AtlasQ9BVX2
HPRD14690
IPIIPI00031597   IPI00760650   IPI01020846   IPI01023002   IPI01020975   IPI01021393   IPI01020698   IPI01021126   IPI01021689   IPI01022133   IPI01021240   
Protein Interaction databases
DIP (DOE-UCLA)Q9BVX2
IntAct (EBI)Q9BVX2
FunCoupENSG00000134291
BioGRIDTMEM106C
STRING (EMBL)TMEM106C
ZODIACTMEM106C
Ontologies - Pathways
QuickGOQ9BVX2
Ontology : AmiGOmolecular_function  protein binding  cellular_component  endoplasmic reticulum membrane  biological_process  membrane  integral component of membrane  
Ontology : EGO-EBImolecular_function  protein binding  cellular_component  endoplasmic reticulum membrane  biological_process  membrane  integral component of membrane  
NDEx NetworkTMEM106C
Atlas of Cancer Signalling NetworkTMEM106C
Wikipedia pathwaysTMEM106C
Orthology - Evolution
OrthoDB79022
GeneTree (enSembl)ENSG00000134291
Phylogenetic Trees/Animal Genes : TreeFamTMEM106C
HOVERGENQ9BVX2
HOGENOMQ9BVX2
Homologs : HomoloGeneTMEM106C
Homology/Alignments : Family Browser (UCSC)TMEM106C
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM106C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM106C
dbVarTMEM106C
ClinVarTMEM106C
1000_GenomesTMEM106C 
Exome Variant ServerTMEM106C
ExAC (Exome Aggregation Consortium)TMEM106C (select the gene name)
Genetic variants : HAPMAP79022
Genomic Variants (DGV)TMEM106C [DGVbeta]
DECIPHERTMEM106C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM106C 
Mutations
ICGC Data PortalTMEM106C 
TCGA Data PortalTMEM106C 
Broad Tumor PortalTMEM106C
OASIS PortalTMEM106C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM106C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM106C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM106C
DgiDB (Drug Gene Interaction Database)TMEM106C
DoCM (Curated mutations)TMEM106C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM106C (select a term)
intoGenTMEM106C
Cancer3DTMEM106C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTMEM106C
Genetic Testing Registry TMEM106C
NextProtQ9BVX2 [Medical]
TSGene79022
GENETestsTMEM106C
Target ValidationTMEM106C
Huge Navigator TMEM106C [HugePedia]
snp3D : Map Gene to Disease79022
BioCentury BCIQTMEM106C
ClinGenTMEM106C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79022
Chemical/Pharm GKB GenePA142670757
Clinical trialTMEM106C
Miscellaneous
canSAR (ICR)TMEM106C (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM106C
EVEXTMEM106C
GoPubMedTMEM106C
iHOPTMEM106C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:45:47 CEST 2017

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