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TMEM115 (transmembrane protein 115)

Identity

Alias (NCBI)PL6
HGNC (Hugo) TMEM115
HGNC Alias symbPL6
HGNC Alias nameplacental protein 6
LocusID (NCBI) 11070
Atlas_Id 56501
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 50354750 and ends at 50359521 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TMEM115   30055
Cards
Entrez_Gene (NCBI)TMEM115    transmembrane protein 115
AliasesPL6
GeneCards (Weizmann)TMEM115
Ensembl hg19 (Hinxton)ENSG00000126062 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000126062 [Gene_View]  ENSG00000126062 [Sequence]  chr3:50354750-50359521 [Contig_View]  TMEM115 [Vega]
ICGC DataPortalENSG00000126062
TCGA cBioPortalTMEM115
AceView (NCBI)TMEM115
Genatlas (Paris)TMEM115
SOURCE (Princeton)TMEM115
Genetics Home Reference (NIH)TMEM115
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM115  -     chr3:50354750-50359521 -  3p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM115  -     3p21.31   [Description]    (hg19-Feb_2009)
GoldenPathTMEM115 - 3p21.31 [CytoView hg19]  TMEM115 - 3p21.31 [CytoView hg38]
ImmunoBaseENSG00000126062
Genome Data Viewer NCBITMEM115 [Mapview hg19]  
OMIM607069   
Gene and transcription
Genbank (Entrez)AK314166 BC011948 BC017367 BF305563 CR457020
RefSeq transcript (Entrez)NM_007024
Consensus coding sequences : CCDS (NCBI)TMEM115
Gene ExpressionTMEM115 [ NCBI-GEO ]   TMEM115 [ EBI - ARRAY_EXPRESS ]   TMEM115 [ SEEK ]   TMEM115 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM115 [ Firebrowse - Broad ]
GenevisibleExpression of TMEM115 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11070
GTEX Portal (Tissue expression)TMEM115
Human Protein AtlasENSG00000126062-TMEM115 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ12893   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ12893  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ12893
PhosPhoSitePlusQ12893
Domains : Interpro (EBI)TMEM115/Pdh1/Rbl19   
Domain families : Pfam (Sanger)DUF1751 (PF08551)   
Domain families : Pfam (NCBI)pfam08551   
Conserved Domain (NCBI)TMEM115
SuperfamilyQ12893
AlphaFold pdb e-kbQ12893   
Human Protein Atlas [tissue]ENSG00000126062-TMEM115 [tissue]
HPRD06144
Protein Interaction databases
DIP (DOE-UCLA)Q12893
IntAct (EBI)Q12893
BioGRIDTMEM115
STRING (EMBL)TMEM115
ZODIACTMEM115
Ontologies - Pathways
QuickGOQ12893
Ontology : AmiGOGolgi membrane  molecular_function  protein binding  nucleus  Golgi apparatus  Golgi apparatus  endoplasmic reticulum to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum  retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum  negative regulation of cell population proliferation  protein transport  integral component of membrane  Golgi cisterna membrane  identical protein binding  
Ontology : EGO-EBIGolgi membrane  molecular_function  protein binding  nucleus  Golgi apparatus  Golgi apparatus  endoplasmic reticulum to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum  retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum  negative regulation of cell population proliferation  protein transport  integral component of membrane  Golgi cisterna membrane  identical protein binding  
NDEx NetworkTMEM115
Atlas of Cancer Signalling NetworkTMEM115
Wikipedia pathwaysTMEM115
Orthology - Evolution
OrthoDB11070
GeneTree (enSembl)ENSG00000126062
Phylogenetic Trees/Animal Genes : TreeFamTMEM115
Homologs : HomoloGeneTMEM115
Homology/Alignments : Family Browser (UCSC)TMEM115
Gene fusions - Rearrangements
Fusion : QuiverTMEM115
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM115 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM115
dbVarTMEM115
ClinVarTMEM115
MonarchTMEM115
1000_GenomesTMEM115 
Exome Variant ServerTMEM115
GNOMAD BrowserENSG00000126062
Varsome BrowserTMEM115
ACMGTMEM115 variants
VarityQ12893
Genomic Variants (DGV)TMEM115 [DGVbeta]
DECIPHERTMEM115 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM115 
Mutations
ICGC Data PortalTMEM115 
TCGA Data PortalTMEM115 
Broad Tumor PortalTMEM115
OASIS PortalTMEM115 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM115  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM115
Mutations and Diseases : HGMDTMEM115
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTMEM115
DgiDB (Drug Gene Interaction Database)TMEM115
DoCM (Curated mutations)TMEM115
CIViC (Clinical Interpretations of Variants in Cancer)TMEM115
Cancer3DTMEM115
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607069   
Orphanet
DisGeNETTMEM115
MedgenTMEM115
Genetic Testing Registry TMEM115
NextProtQ12893 [Medical]
GENETestsTMEM115
Target ValidationTMEM115
Huge Navigator TMEM115 [HugePedia]
ClinGenTMEM115
Clinical trials, drugs, therapy
MyCancerGenomeTMEM115
Protein Interactions : CTDTMEM115
Pharm GKB GenePA143485636
PharosQ12893
Clinical trialTMEM115
Miscellaneous
canSAR (ICR)TMEM115
HarmonizomeTMEM115
DataMed IndexTMEM115
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTMEM115
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:35:23 CEST 2021

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