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TMEM116 (transmembrane protein 116)

Identity

Alias (NCBI)-
HGNC (Hugo) TMEM116
HGNC Alias symbFLJ90167
LocusID (NCBI) 89894
Atlas_Id 74782
Location 12q24.13  [Link to chromosome band 12q24]
Location_base_pair Starts at 111931283 and ends at 112013219 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TMEM116 (12q24.13) / SOCS2 (12q22)TMEM116 (12q24.13) / TMEM116 (12q24.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TMEM116   25084
Cards
Entrez_Gene (NCBI)TMEM116    transmembrane protein 116
Aliases
GeneCards (Weizmann)TMEM116
Ensembl hg19 (Hinxton)ENSG00000198270 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198270 [Gene_View]  ENSG00000198270 [Sequence]  chr12:111931283-112013219 [Contig_View]  TMEM116 [Vega]
ICGC DataPortalENSG00000198270
TCGA cBioPortalTMEM116
AceView (NCBI)TMEM116
Genatlas (Paris)TMEM116
SOURCE (Princeton)TMEM116
Genetics Home Reference (NIH)TMEM116
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM116  -     chr12:111931283-112013219 -  12q24.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM116  -     12q24.13   [Description]    (hg19-Feb_2009)
GoldenPathTMEM116 - 12q24.13 [CytoView hg19]  TMEM116 - 12q24.13 [CytoView hg38]
ImmunoBaseENSG00000198270
Genome Data Viewer NCBITMEM116 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK021528 AK074648 AK092832 AL519857 AL833501
RefSeq transcript (Entrez)NM_001193453 NM_001193531 NM_001294314 NM_138341
Consensus coding sequences : CCDS (NCBI)TMEM116
Gene ExpressionTMEM116 [ NCBI-GEO ]   TMEM116 [ EBI - ARRAY_EXPRESS ]   TMEM116 [ SEEK ]   TMEM116 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM116 [ Firebrowse - Broad ]
GenevisibleExpression of TMEM116 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)89894
GTEX Portal (Tissue expression)TMEM116
Human Protein AtlasENSG00000198270-TMEM116 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NCL8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NCL8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NCL8
PhosPhoSitePlusQ8NCL8
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TMEM116
SuperfamilyQ8NCL8
AlphaFold pdb e-kbQ8NCL8   
Human Protein Atlas [tissue]ENSG00000198270-TMEM116 [tissue]
HPRD11275
Protein Interaction databases
DIP (DOE-UCLA)Q8NCL8
IntAct (EBI)Q8NCL8
BioGRIDTMEM116
STRING (EMBL)TMEM116
ZODIACTMEM116
Ontologies - Pathways
QuickGOQ8NCL8
Ontology : AmiGOmolecular_function  cellular_component  biological_process  integral component of membrane  
Ontology : EGO-EBImolecular_function  cellular_component  biological_process  integral component of membrane  
NDEx NetworkTMEM116
Atlas of Cancer Signalling NetworkTMEM116
Wikipedia pathwaysTMEM116
Orthology - Evolution
OrthoDB89894
GeneTree (enSembl)ENSG00000198270
Phylogenetic Trees/Animal Genes : TreeFamTMEM116
Homologs : HomoloGeneTMEM116
Homology/Alignments : Family Browser (UCSC)TMEM116
Gene fusions - Rearrangements
Fusion : QuiverTMEM116
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM116 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM116
dbVarTMEM116
ClinVarTMEM116
MonarchTMEM116
1000_GenomesTMEM116 
Exome Variant ServerTMEM116
GNOMAD BrowserENSG00000198270
Varsome BrowserTMEM116
ACMGTMEM116 variants
VarityQ8NCL8
Genomic Variants (DGV)TMEM116 [DGVbeta]
DECIPHERTMEM116 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM116 
Mutations
ICGC Data PortalTMEM116 
TCGA Data PortalTMEM116 
Broad Tumor PortalTMEM116
OASIS PortalTMEM116 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM116  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM116
Mutations and Diseases : HGMDTMEM116
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTMEM116
DgiDB (Drug Gene Interaction Database)TMEM116
DoCM (Curated mutations)TMEM116
CIViC (Clinical Interpretations of Variants in Cancer)TMEM116
Cancer3DTMEM116
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTMEM116
MedgenTMEM116
Genetic Testing Registry TMEM116
NextProtQ8NCL8 [Medical]
GENETestsTMEM116
Target ValidationTMEM116
Huge Navigator TMEM116 [HugePedia]
ClinGenTMEM116
Clinical trials, drugs, therapy
MyCancerGenomeTMEM116
Protein Interactions : CTDTMEM116
Pharm GKB GenePA143485637
PharosQ8NCL8
Clinical trialTMEM116
Miscellaneous
canSAR (ICR)TMEM116
HarmonizomeTMEM116
DataMed IndexTMEM116
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTMEM116
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:25:45 CEST 2021

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