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TMEM116 (transmembrane protein 116)

Identity

Alias_symbol (synonym)FLJ90167
Other alias-
HGNC (Hugo) TMEM116
LocusID (NCBI) 89894
Atlas_Id 74782
Location 12q24.13  [Link to chromosome band 12q24]
Location_base_pair Starts at 111931283 and ends at 112013219 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TMEM116 (12q24.13) / SOCS2 (12q22)TMEM116 (12q24.13) / TMEM116 (12q24.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TMEM116   25084
Cards
Entrez_Gene (NCBI)TMEM116  89894  transmembrane protein 116
Aliases
GeneCards (Weizmann)TMEM116
Ensembl hg19 (Hinxton)ENSG00000198270 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198270 [Gene_View]  chr12:111931283-112013219 [Contig_View]  TMEM116 [Vega]
ICGC DataPortalENSG00000198270
TCGA cBioPortalTMEM116
AceView (NCBI)TMEM116
Genatlas (Paris)TMEM116
WikiGenes89894
SOURCE (Princeton)TMEM116
Genetics Home Reference (NIH)TMEM116
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM116  -     chr12:111931283-112013219 -  12q24.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM116  -     12q24.13   [Description]    (hg19-Feb_2009)
EnsemblTMEM116 - 12q24.13 [CytoView hg19]  TMEM116 - 12q24.13 [CytoView hg38]
Mapping of homologs : NCBITMEM116 [Mapview hg19]  TMEM116 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK021528 AK074648 AK092832 AL519857 AL833501
RefSeq transcript (Entrez)NM_001193453 NM_001193531 NM_001294314 NM_138341
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM116
Cluster EST : UnigeneHs.735999 [ NCBI ]
CGAP (NCI)Hs.735999
Alternative Splicing GalleryENSG00000198270
Gene ExpressionTMEM116 [ NCBI-GEO ]   TMEM116 [ EBI - ARRAY_EXPRESS ]   TMEM116 [ SEEK ]   TMEM116 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM116 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)89894
GTEX Portal (Tissue expression)TMEM116
Human Protein AtlasENSG00000198270-TMEM116 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NCL8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NCL8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NCL8
Splice isoforms : SwissVarQ8NCL8
PhosPhoSitePlusQ8NCL8
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TMEM116
DMDM Disease mutations89894
Blocks (Seattle)TMEM116
SuperfamilyQ8NCL8
Human Protein Atlas [tissue]ENSG00000198270-TMEM116 [tissue]
Peptide AtlasQ8NCL8
HPRD11275
IPIIPI00184382   IPI00306613   IPI01022703   IPI01022782   IPI01022936   IPI01021880   IPI00983271   IPI01021440   IPI01021610   IPI01021766   
Protein Interaction databases
DIP (DOE-UCLA)Q8NCL8
IntAct (EBI)Q8NCL8
FunCoupENSG00000198270
BioGRIDTMEM116
STRING (EMBL)TMEM116
ZODIACTMEM116
Ontologies - Pathways
QuickGOQ8NCL8
Ontology : AmiGOmolecular_function  cellular_component  biological_process  integral component of membrane  
Ontology : EGO-EBImolecular_function  cellular_component  biological_process  integral component of membrane  
NDEx NetworkTMEM116
Atlas of Cancer Signalling NetworkTMEM116
Wikipedia pathwaysTMEM116
Orthology - Evolution
OrthoDB89894
GeneTree (enSembl)ENSG00000198270
Phylogenetic Trees/Animal Genes : TreeFamTMEM116
HOVERGENQ8NCL8
HOGENOMQ8NCL8
Homologs : HomoloGeneTMEM116
Homology/Alignments : Family Browser (UCSC)TMEM116
Gene fusions - Rearrangements
Tumor Fusion PortalTMEM116
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM116 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM116
dbVarTMEM116
ClinVarTMEM116
1000_GenomesTMEM116 
Exome Variant ServerTMEM116
ExAC (Exome Aggregation Consortium)ENSG00000198270
GNOMAD BrowserENSG00000198270
Genetic variants : HAPMAP89894
Genomic Variants (DGV)TMEM116 [DGVbeta]
DECIPHERTMEM116 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM116 
Mutations
ICGC Data PortalTMEM116 
TCGA Data PortalTMEM116 
Broad Tumor PortalTMEM116
OASIS PortalTMEM116 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM116  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTMEM116
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM116
DgiDB (Drug Gene Interaction Database)TMEM116
DoCM (Curated mutations)TMEM116 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM116 (select a term)
intoGenTMEM116
Cancer3DTMEM116(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTMEM116
MedgenTMEM116
Genetic Testing Registry TMEM116
NextProtQ8NCL8 [Medical]
TSGene89894
GENETestsTMEM116
Target ValidationTMEM116
Huge Navigator TMEM116 [HugePedia]
snp3D : Map Gene to Disease89894
BioCentury BCIQTMEM116
ClinGenTMEM116
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD89894
Chemical/Pharm GKB GenePA143485637
Clinical trialTMEM116
Miscellaneous
canSAR (ICR)TMEM116 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM116
EVEXTMEM116
GoPubMedTMEM116
iHOPTMEM116
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:27:37 CET 2017

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